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185 related items for PubMed ID: 9303567

  • 1. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors.
    Price GW, Burton MJ, Collin LJ, Duckworth M, Gaster L, Göthert M, Jones BJ, Roberts C, Watson JM, Middlemiss DN.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep; 356(3):312-20. PubMed ID: 9303567
    [Abstract] [Full Text] [Related]

  • 2. Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors.
    Schlicker E, Fink K, Molderings GJ, Price GW, Duckworth M, Gaster L, Middlemiss DN, Zentner J, Likungu J, Göthert M.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep; 356(3):321-7. PubMed ID: 9303568
    [Abstract] [Full Text] [Related]

  • 3. How efficacious are 5-HT1B/D receptor ligands: an answer from GTP gamma S binding studies with stably transfected C6-glial cell lines.
    Pauwels PJ, Tardif S, Palmier C, Wurch T, Colpaert FC.
    Neuropharmacology; 1997 Sep; 36(4-5):499-512. PubMed ID: 9225275
    [Abstract] [Full Text] [Related]

  • 4. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 1998 Sep; 125(1):202-8. PubMed ID: 9776361
    [Abstract] [Full Text] [Related]

  • 5. Actions of roxindole at recombinant human dopamine D2, D3 and D4 and serotonin 5-HT1A, 5-HT1B and 5-HT1D receptors.
    Newman-Tancredi A, Cussac D, Audinot V, Millan MJ.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Jun; 359(6):447-53. PubMed ID: 10431754
    [Abstract] [Full Text] [Related]

  • 6. Importance of h5-HT1B receptor selectivity for 5-HT terminal autoreceptor activity: an in vivo microdialysis study in the freely-moving guinea-pig.
    Roberts C, Price GW, Gaster L, Jones BJ, Middlemiss DN, Routledge C.
    Neuropharmacology; 1997 Jun; 36(4-5):549-57. PubMed ID: 9225280
    [Abstract] [Full Text] [Related]

  • 7. 5-HT-stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding as an assay for functional activation of G proteins coupled with 5-HT1B receptors in rat striatal membranes.
    Odagaki Y, Toyoshima R.
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Feb; 372(5):335-45. PubMed ID: 16491386
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.
    Sternfeld F, Guiblin AR, Jelley RA, Matassa VG, Reeve AJ, Hunt PA, Beer MS, Heald A, Stanton JA, Sohal B, Watt AP, Street LJ.
    J Med Chem; 1999 Feb 25; 42(4):677-90. PubMed ID: 10052975
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functions.
    Marcoli M, Maura G, Munari C, Ruelle A, Raiteri M.
    Br J Pharmacol; 1999 Feb 25; 126(3):607-12. PubMed ID: 10188970
    [Abstract] [Full Text] [Related]

  • 10. Stimulation of 5-HT1B receptors causes hypothermia in the guinea pig.
    Hagan JJ, Slade PD, Gaster L, Jeffrey P, Hatcher JP, Middlemiss DN.
    Eur J Pharmacol; 1997 Jul 23; 331(2-3):169-74. PubMed ID: 9274976
    [Abstract] [Full Text] [Related]

  • 11. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
    [Abstract] [Full Text] [Related]

  • 12. Role of 5-HT1B/D receptors in canine gastric accommodation: effect of sumatriptan and 5-HT1B/D receptor antagonists.
    De Ponti F, Crema F, Moro E, Nardelli G, Frigo G, Crema A.
    Am J Physiol Gastrointest Liver Physiol; 2003 Jul 09; 285(1):G96-104. PubMed ID: 12646419
    [Abstract] [Full Text] [Related]

  • 13. SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
    Scott C, Soffin EM, Hill M, Atkinson PJ, Langmead CJ, Wren PB, Faedo S, Gordon LJ, Price GW, Bromidge S, Johnson CN, Hagan JJ, Watson J.
    Eur J Pharmacol; 2006 Apr 24; 536(1-2):54-61. PubMed ID: 16571351
    [Abstract] [Full Text] [Related]

  • 14. Characterization of human serotonin 1D and 1B receptors using [3H]-GR-125743, a novel radiolabelled serotonin 5HT1D/1B receptor antagonist.
    Doménech T, Beleta J, Palacios JM.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Sep 24; 356(3):328-34. PubMed ID: 9303569
    [Abstract] [Full Text] [Related]

  • 15. SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'methyl-4'-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): a novel, potent and selective 5-HT1B receptor antagonist.
    Scott C, Langmead CJ, Clarke KL, Wyman P, Smith PW, Starr KR, Dawson LA, Price GW, Hagan JJ, Watson J.
    Neuropharmacology; 2006 Jun 24; 50(8):984-90. PubMed ID: 16546225
    [Abstract] [Full Text] [Related]

  • 16. GR127935 acts as a partial agonist at recombinant human 5-HT1D alpha and 5-HT1D beta receptors.
    Watson JM, Burton MJ, Price GW, Jones BJ, Middlemiss DN.
    Eur J Pharmacol; 1996 Oct 31; 314(3):365-72. PubMed ID: 8957260
    [Abstract] [Full Text] [Related]

  • 17. Magnitude of 5-HT1B and 5-HT1A receptor activation in guinea-pig and rat brain: evidence from sumatriptan dimer-mediated [35S]GTPgammaS binding responses.
    Dupuis DS, Perez M, Halazy S, Colpaert FC, Pauwels PJ.
    Brain Res Mol Brain Res; 1999 Apr 06; 67(1):107-23. PubMed ID: 10101238
    [Abstract] [Full Text] [Related]

  • 18. 3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.
    Chambers MS, Street LJ, Goodacre S, Hobbs SC, Hunt P, Jelley RA, Matassa VG, Reeve AJ, Sternfeld F, Beer MS, Stanton JA, Rathbone D, Watt AP, MacLeod AM.
    J Med Chem; 1999 Feb 25; 42(4):691-705. PubMed ID: 10052976
    [Abstract] [Full Text] [Related]

  • 19. Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: a structure-affinity investigation.
    Law H, Dukat M, Teitler M, Lee DK, Mazzocco L, Kamboj R, Rampersad V, Prisinzano T, Glennon RA.
    J Med Chem; 1998 Jun 18; 41(13):2243-51. PubMed ID: 9632357
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological analysis of G-protein activation mediated by guinea-pig recombinant 5-HT1B receptors in C6-glial cells: similarities with the human 5-HT1B receptor.
    Pauwels PJ, Wurch T, Palmier C, Colpaert FC.
    Br J Pharmacol; 1998 Jan 18; 123(1):51-62. PubMed ID: 9484854
    [Abstract] [Full Text] [Related]


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