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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

93 related items for PubMed ID: 9305960

  • 1. Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
    Kent UM, Hanna IH, Szklarz GD, Vaz AD, Halpert JR, Bend JR, Hollenberg PF.
    Biochemistry; 1997 Sep 30; 36(39):11707-16. PubMed ID: 9305960
    [Abstract] [Full Text] [Related]

  • 2. Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole.
    Kent UM, Bend JR, Chamberlin BA, Gage DA, Hollenberg PF.
    Chem Res Toxicol; 1997 May 30; 10(5):600-8. PubMed ID: 9168259
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  • 3. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May 30; 10(5):589-99. PubMed ID: 9168258
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  • 4. Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine.
    Kent UM, Pascual L, Roof RA, Ballou DP, Hollenberg PF.
    Arch Biochem Biophys; 2004 Mar 15; 423(2):277-87. PubMed ID: 15001392
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  • 5. Identification of amino acid residues involved in the inactivation of cytochrome P450 2B1 by two acetylenic compounds: the role of three residues in nonsubstrate recognition Sites.
    Von Weymarn LB, Sridar C, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Oct 15; 311(1):71-9. PubMed ID: 15178696
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  • 6. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
    Goosen TC, Mills DE, Hollenberg PF.
    J Pharmacol Exp Ther; 2001 Jan 15; 296(1):198-206. PubMed ID: 11123381
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  • 7. Molecular basis for the differences in lidocaine binding and regioselectivity of oxidation by cytochromes P450 2B1 and 2B2.
    Hanna IH, Roberts ES, Hollenberg PF.
    Biochemistry; 1998 Jan 06; 37(1):311-8. PubMed ID: 9425052
    [Abstract] [Full Text] [Related]

  • 8. The functional role of threonine-205 in the mechanism-based inactivation of P450 2B1 by two ethynyl substrates: the importance of the F helix in catalysis.
    Lin HL, Kent UM, Zhang H, Waskell L, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Dec 06; 311(3):855-63. PubMed ID: 15302894
    [Abstract] [Full Text] [Related]

  • 9. Probing the active site of cytochrome P450 2B1: metabolism of 7-alkoxycoumarins by the wild type and five site-directed mutants.
    Kobayashi Y, Fang X, Szklarz GD, Halpert JR.
    Biochemistry; 1998 May 12; 37(19):6679-88. PubMed ID: 9578551
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  • 10. Peroxynitrite-mediated nitration of tyrosine and inactivation of the catalytic activity of cytochrome P450 2B1.
    Roberts ES, Lin Hl, Crowley JR, Vuletich JL, Osawa Y, Hollenberg PF.
    Chem Res Toxicol; 1998 Sep 12; 11(9):1067-74. PubMed ID: 9760281
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  • 12. Identification of the heme adduct and an active site peptide modified during mechanism-based inactivation of rat liver cytochrome P450 2B1 by secobarbital.
    He K, Falick AM, Chen B, Nilsson F, Correia MA.
    Chem Res Toxicol; 1996 Sep 12; 9(3):614-22. PubMed ID: 8728507
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  • 15. Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities.
    Hanna IH, Teiber JF, Kokones KL, Hollenberg PF.
    Arch Biochem Biophys; 1998 Feb 15; 350(2):324-32. PubMed ID: 9473308
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  • 18. Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitrite.
    Lin HL, Kent UM, Zhang H, Waskell L, Hollenberg PF.
    Chem Res Toxicol; 2003 Feb 15; 16(2):129-36. PubMed ID: 12588183
    [Abstract] [Full Text] [Related]

  • 19. Inactivation of cytochrome P450 2B1 by benzyl isothiocyanate, a chemopreventative agent from cruciferous vegetables.
    Goosen TC, Kent UM, Brand L, Hollenberg PF.
    Chem Res Toxicol; 2000 Dec 15; 13(12):1349-59. PubMed ID: 11123978
    [Abstract] [Full Text] [Related]

  • 20. N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    Knickle LC, Philpot RM, Bend JR.
    J Pharmacol Exp Ther; 1994 Jul 15; 270(1):377-85. PubMed ID: 8035335
    [Abstract] [Full Text] [Related]

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