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410 related items for PubMed ID: 9307274

  • 1. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W, Chiao PJ.
    Cancer Res; 1997 Sep 15; 57(18):3929-34. PubMed ID: 9307274
    [Abstract] [Full Text] [Related]

  • 2. Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.
    Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.
    Clin Cancer Res; 2002 Nov 15; 8(11):3628-38. PubMed ID: 12429655
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of the tumor suppressor gene Smad4/DPC4 induces p21waf1 expression and growth inhibition in human carcinoma cells.
    Hunt KK, Fleming JB, Abramian A, Zhang L, Evans DB, Chiao PJ.
    Cancer Res; 1998 Dec 15; 58(24):5656-61. PubMed ID: 9865717
    [Abstract] [Full Text] [Related]

  • 4. Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma.
    Venkatasubbarao K, Ahmed MM, Mohiuddin M, Swiderski C, Lee E, Gower WR, Salhab KF, McGrath P, Strodel W, Freeman JW.
    Anticancer Res; 2000 Dec 15; 20(1A):43-51. PubMed ID: 10769633
    [Abstract] [Full Text] [Related]

  • 5. DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells.
    de Winter JP, Roelen BA, ten Dijke P, van der Burg B, van den Eijnden-van Raaij AJ.
    Oncogene; 1997 Apr 24; 14(16):1891-9. PubMed ID: 9150356
    [Abstract] [Full Text] [Related]

  • 6. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT, Bartlett C, Henry E, Weissman BE.
    J Cell Physiol; 2003 Mar 24; 194(3):289-302. PubMed ID: 12548549
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  • 7. Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle.
    Chiao PJ, Hunt KK, Grau AM, Abramian A, Fleming J, Zhang W, Breslin T, Abbruzzese JL, Evans DB.
    Ann N Y Acad Sci; 1999 Jun 30; 880():31-7. PubMed ID: 10415848
    [Abstract] [Full Text] [Related]

  • 8. Smad4-independent regulation of p21/WAF1 by transforming growth factor-beta.
    Ijichi H, Otsuka M, Tateishi K, Ikenoue T, Kawakami T, Kanai F, Arakawa Y, Seki N, Shimizu K, Miyazono K, Kawabe T, Omata M.
    Oncogene; 2004 Feb 05; 23(5):1043-51. PubMed ID: 14762439
    [Abstract] [Full Text] [Related]

  • 9. Sensitivity to transforming growth factor beta 1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21waf1 induction are important early events.
    Malliri A, Yeudall WA, Nikolic M, Crouch DH, Parkinson EK, Ozanne B.
    Cell Growth Differ; 1996 Oct 05; 7(10):1291-304. PubMed ID: 8891333
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  • 11. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
    Jonckheere N, Perrais M, Mariette C, Batra SK, Aubert JP, Pigny P, Van Seuningen I.
    Oncogene; 2004 Jul 29; 23(34):5729-38. PubMed ID: 15184872
    [Abstract] [Full Text] [Related]

  • 12. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS, Ahmed MM.
    Oncogene; 2002 Nov 07; 21(51):7883-90. PubMed ID: 12420225
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  • 14. Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas.
    Goggins M, Shekher M, Turnacioglu K, Yeo CJ, Hruban RH, Kern SE.
    Cancer Res; 1998 Dec 01; 58(23):5329-32. PubMed ID: 9850059
    [Abstract] [Full Text] [Related]

  • 15. DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression.
    Schwarte-Waldhoff I, Klein S, Blass-Kampmann S, Hintelmann A, Eilert C, Dreschers S, Kalthoff H, Hahn SA, Schmiegel W.
    Oncogene; 1999 May 20; 18(20):3152-8. PubMed ID: 10340387
    [Abstract] [Full Text] [Related]

  • 16. Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.
    Nicolás FJ, Hill CS.
    Oncogene; 2003 Jun 12; 22(24):3698-711. PubMed ID: 12802277
    [Abstract] [Full Text] [Related]

  • 17. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G, Schwarz RE, Higgins L, McEnroe G, Chakravarty S, Dugar S, Reiss M.
    Cancer Res; 2004 Aug 01; 64(15):5200-11. PubMed ID: 15289325
    [Abstract] [Full Text] [Related]

  • 18. Overexpression of transforming growth factor (TGF) beta1 type II receptor restores TGF-beta1 sensitivity and signaling in human prostate cancer cells.
    Guo Y, Kyprianou N.
    Cell Growth Differ; 1998 Feb 01; 9(2):185-93. PubMed ID: 9486855
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  • 20. Regulatory mechanisms for transforming growth factor beta as an autocrine inhibitor in human hepatocellular carcinoma: implications for roles of smads in its growth.
    Matsuzaki K, Date M, Furukawa F, Tahashi Y, Matsushita M, Sugano Y, Yamashiki N, Nakagawa T, Seki T, Nishizawa M, Fujisawa J, Inoue K.
    Hepatology; 2000 Aug 01; 32(2):218-27. PubMed ID: 10915727
    [Abstract] [Full Text] [Related]

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