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Journal Abstract Search

171 related items for PubMed ID: 9312066

  • 1. Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains.
    McPhie DL, Lee RK, Eckman CB, Olstein DH, Durham SP, Yager D, Younkin SG, Wurtman RJ, Neve RL.
    J Biol Chem; 1997 Oct 03; 272(40):24743-6. PubMed ID: 9312066
    [Abstract] [Full Text] [Related]

  • 2. beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations.
    McPhie DL, Golde T, Eckman CB, Yager D, Brant JB, Neve RL.
    Brain Res Mol Brain Res; 2001 Dec 16; 97(1):103-13. PubMed ID: 11744168
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  • 4. Enhanced BK-induced calcium responsiveness in PC12 cells expressing the C100 fragment of the amyloid precursor protein.
    Pascale A, Bhagavan S, Nelson TJ, Neve RL, McPhie DL, Etcheberrigaray R.
    Brain Res Mol Brain Res; 1999 Oct 01; 72(2):205-13. PubMed ID: 10529479
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  • 5. APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells.
    De Chiara G, Marcocci ME, Civitelli L, Argnani R, Piacentini R, Ripoli C, Manservigi R, Grassi C, Garaci E, Palamara AT.
    PLoS One; 2010 Nov 15; 5(11):e13989. PubMed ID: 21085580
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  • 6. Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
    Wiltfang J, Esselmann H, Cupers P, Neumann M, Kretzschmar H, Beyermann M, Schleuder D, Jahn H, Rüther E, Kornhuber J, Annaert W, De Strooper B, Saftig P.
    J Biol Chem; 2001 Nov 16; 276(46):42645-57. PubMed ID: 11526104
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  • 7. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons.
    Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM.
    J Biol Chem; 2003 Feb 14; 278(7):4458-66. PubMed ID: 12480937
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  • 8. The vacuolar H(+)-ATPase inhibitor bafilomycin A1 differentially affects proteolytic processing of mutant and wild-type beta-amyloid precursor protein.
    Haass C, Capell A, Citron M, Teplow DB, Selkoe DJ.
    J Biol Chem; 1995 Mar 17; 270(11):6186-92. PubMed ID: 7890753
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  • 10. Expression of potentially amyloidogenic derivatives of the Alzheimer amyloid precursor protein in cultured 293 cells.
    Johnstone EM, Oltersdorf T, Bales KR, Chaney MO, Santerre RF, Little SP.
    Neurosci Lett; 1994 Oct 24; 180(2):151-4. PubMed ID: 7700569
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  • 12. Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants.
    Gorman PM, Kim S, Guo M, Melnyk RA, McLaurin J, Fraser PE, Bowie JU, Chakrabartty A.
    BMC Neurosci; 2008 Jan 30; 9():17. PubMed ID: 18234110
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  • 13. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J, Williamson NA, Hill AF, Sernee MF, Masters CL, Small DH.
    J Neurosci Res; 2003 Nov 01; 74(3):378-85. PubMed ID: 14598314
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  • 15. Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner.
    Vincent B, Smith JD.
    Eur J Neurosci; 2001 Jul 01; 14(2):256-66. PubMed ID: 11553277
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  • 17. The amyloid beta protein precursor mutations linked to familial Alzheimer's disease alter processing in a way that fosters amyloid deposition.
    Younkin SG.
    Tohoku J Exp Med; 1994 Nov 01; 174(3):217-23. PubMed ID: 7761987
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  • 18. Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.
    Gandy S, Zhang YW, Ikin A, Schmidt SD, Bogush A, Levy E, Sheffield R, Nixon RA, Liao FF, Mathews PM, Xu H, Ehrlich ME.
    J Neurochem; 2007 Aug 01; 102(3):619-26. PubMed ID: 17630980
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  • 19. Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.
    Shi XP, Tugusheva K, Bruce JE, Lucka A, Chen-Dodson E, Hu B, Wu GX, Price E, Register RB, Lineberger J, Miller R, Tang MJ, Espeseth A, Kahana J, Wolfe A, Crouthamel MC, Sankaranarayanan S, Simon A, Chen L, Lai MT, Pietrak B, DiMuzio J, Li Y, Xu M, Huang Q, Garsky V, Sardana MK, Hazuda DJ.
    J Alzheimers Dis; 2005 Apr 01; 7(2):139-48; discussion 173-80. PubMed ID: 15851852
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  • 20. The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
    Nunan J, Shearman MS, Checler F, Cappai R, Evin G, Beyreuther K, Masters CL, Small DH.
    Eur J Biochem; 2001 Oct 01; 268(20):5329-36. PubMed ID: 11606195
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