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116 related items for PubMed ID: 9352462

  • 1. Potent in vivo inhibitors of rat renin: analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site.
    Sueiras-Diaz J, Jones DM, Szelke M, Leckie BJ, Beattie SR, Beattie C, Morton JJ.
    J Pept Res; 1997 Oct; 50(4):239-47. PubMed ID: 9352462
    [Abstract] [Full Text] [Related]

  • 2. Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions.
    Sawyer TK, Pals DT, Mao B, Staples DJ, de Vaux AE, Maggiora LL, Affholter JA, Kati W, Duchamp D, Hester JB.
    J Med Chem; 1988 Jan; 31(1):18-30. PubMed ID: 3275777
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and renin inhibitory activity of angiotensinogen analogues having dehydrostatine, Leu psi [CH2S]Val, or Leu psi [CH2SO]Val at the P1-P1' cleavage site.
    Smith CW, Saneii HH, Sawyer TK, Pals DT, Scahill TA, Kamdar BV, Lawson JA.
    J Med Chem; 1988 Jul; 31(7):1377-82. PubMed ID: 3290486
    [Abstract] [Full Text] [Related]

  • 4. Renin inhibitors containing psi[CH2O] pseudopeptide inserts.
    TenBrink RE, Pals DT, Harris DW, Johnson GA.
    J Med Chem; 1988 Mar; 31(3):671-7. PubMed ID: 3279210
    [Abstract] [Full Text] [Related]

  • 5. New renin inhibitors containing novel analogues of statine.
    Jones DM, Sueiras-Diaz J, Szelke M, Leckie BJ, Beattie SR, Morton J, Neidle S, Kuroda R.
    J Pept Res; 1997 Aug; 50(2):109-21. PubMed ID: 9273895
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological activity of potent, low molecular weight renin inhibitors.
    Sueiras-Diaz J, Jones DM, Szelke M, Deinum J, Svensson L, Westerlund C, Sohtell M.
    J Pept Res; 1997 Oct; 50(4):248-61. PubMed ID: 9352463
    [Abstract] [Full Text] [Related]

  • 7. Inhibitors of rat renin and their use in experimental hypertension.
    Beattie EC, Morton JJ, Leckie BJ, Sueiras-Diaz J, Jones DM, Szelke M.
    J Hypertens Suppl; 1989 Dec; 7(6):S220-1. PubMed ID: 2698930
    [Abstract] [Full Text] [Related]

  • 8. X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.
    Dealwis CG, Frazao C, Badasso M, Cooper JB, Tickle IJ, Driessen H, Blundell TL, Murakami K, Miyazaki H, Sueiras-Diaz J.
    J Mol Biol; 1994 Feb 11; 236(1):342-60. PubMed ID: 8107115
    [Abstract] [Full Text] [Related]

  • 9. Structure-conformation relationships of synthetic peptide inhibitors of human renin studied by resonance energy transfer and molecular modeling.
    Epps DE, Mao B, Staples DJ, Sawyer TK.
    Int J Pept Protein Res; 1988 Jan 11; 31(1):22-34. PubMed ID: 3284834
    [Abstract] [Full Text] [Related]

  • 10. Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.
    Luly JR, BaMaung N, Soderquist J, Fung AK, Stein H, Kleinert HD, Marcotte PA, Egan DA, Bopp B, Merits I.
    J Med Chem; 1988 Dec 11; 31(12):2264-76. PubMed ID: 3143009
    [Abstract] [Full Text] [Related]

  • 11. HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs.
    Sawyer TK, Staples DJ, Liu L, Tomasselli AG, Hui JO, O'Connell K, Schostarez H, Hester JB, Moon J, Howe WJ.
    Int J Pept Protein Res; 1992 Dec 11; 40(3-4):274-81. PubMed ID: 1478785
    [Abstract] [Full Text] [Related]

  • 12. Renin inhibitors. Synthesis of transition-state analogue inhibitors containing phosphorus acid derivatives at the scissile bond.
    Allen MC, Fuhrer W, Tuck B, Wade R, Wood JM.
    J Med Chem; 1989 Jul 11; 32(7):1652-61. PubMed ID: 2661820
    [Abstract] [Full Text] [Related]

  • 13. alpha-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model.
    Thaisrivongs S, Pals DT, Lawson JA, Turner SR, Harris DW.
    J Med Chem; 1987 Mar 11; 30(3):536-41. PubMed ID: 3546690
    [Abstract] [Full Text] [Related]

  • 14. Renin cleavage of a human kidney renin substrate analogous to human angiotensinogen, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH, that is human renin specific and is resistant to cathepsin D.
    Poe M, Wu JK, Lin TY, Hoogsteen K, Bull HG, Slater EE.
    Anal Biochem; 1984 Aug 01; 140(2):459-67. PubMed ID: 6385771
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo.
    Thaisrivongs S, Pals DT, Harris DW, Kati WM, Turner SR.
    J Med Chem; 1986 Oct 01; 29(10):2088-93. PubMed ID: 3531518
    [Abstract] [Full Text] [Related]

  • 16. New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon.
    Tree M, Atrash B, Donovan B, Gamble J, Hallett A, Hughes M, Jones DM, Leckie B, Lever AF, Morton JJ.
    J Hypertens; 1983 Dec 01; 1(4):399-403. PubMed ID: 6398331
    [Abstract] [Full Text] [Related]

  • 17. New inhibitors of human renin that contain novel Leu-Val replacements. Examination of the P1 site.
    Luly JR, Bolis G, BaMaung N, Soderquist J, Dellaria JF, Stein H, Cohen J, Perun TJ, Greer J, Plattner JJ.
    J Med Chem; 1988 Mar 01; 31(3):532-9. PubMed ID: 3279206
    [Abstract] [Full Text] [Related]

  • 18. Renin vs. angiotensin-converting enzyme inhibition in the rat: consequences for plasma and renal tissue angiotensin.
    Allan DR, Hui KY, Coletti C, Hollenberg NK.
    J Pharmacol Exp Ther; 1997 Nov 01; 283(2):661-5. PubMed ID: 9353383
    [Abstract] [Full Text] [Related]

  • 19. The His-Pro-Phe motif of angiotensinogen is a crucial determinant of the substrate specificity of renin.
    Nakagawa T, Akaki J, Satou R, Takaya M, Iwata H, Katsurada A, Nishiuchi K, Ohmura Y, Suzuki F, Nakamura Y.
    Biol Chem; 2007 Feb 01; 388(2):237-46. PubMed ID: 17261087
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of renin by angiotensinogen peptide fragments containing the hydroxy amino acid residue 5-amino-3-hydroxy-7-methyloctanoic acid.
    Johnson RL, Verschoor K.
    J Med Chem; 1983 Oct 01; 26(10):1457-62. PubMed ID: 6352942
    [Abstract] [Full Text] [Related]

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