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126 related items for PubMed ID: 9353287

  • 1. Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage.
    Vito P, Ghayur T, D'Adamio L.
    J Biol Chem; 1997 Nov 07; 272(45):28315-20. PubMed ID: 9353287
    [Abstract] [Full Text] [Related]

  • 2. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.
    Vito P, Wolozin B, Ganjei JK, Iwasaki K, Lacanà E, D'Adamio L.
    J Biol Chem; 1996 Dec 06; 271(49):31025-8. PubMed ID: 8940094
    [Abstract] [Full Text] [Related]

  • 3. Presenilins are processed by caspase-type proteases.
    Loetscher H, Deuschle U, Brockhaus M, Reinhardt D, Nelboeck P, Mous J, Grünberg J, Haass C, Jacobsen H.
    J Biol Chem; 1997 Aug 15; 272(33):20655-9. PubMed ID: 9252383
    [Abstract] [Full Text] [Related]

  • 4. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.
    Kim TW, Pettingell WH, Jung YK, Kovacs DM, Tanzi RE.
    Science; 1997 Jul 18; 277(5324):373-6. PubMed ID: 9219695
    [Abstract] [Full Text] [Related]

  • 5. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2.
    Choi EK, Zaidi NF, Miller JS, Crowley AC, Merriam DE, Lilliehook C, Buxbaum JD, Wasco W.
    J Biol Chem; 2001 Jun 01; 276(22):19197-204. PubMed ID: 11278424
    [Abstract] [Full Text] [Related]

  • 6. Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.
    Alves da Costa C, Paitel E, Mattson MP, Amson R, Telerman A, Ancolio K, Checler F.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):4043-8. PubMed ID: 11904448
    [Abstract] [Full Text] [Related]

  • 7. The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
    Alves da Costa C, Mattson MP, Ancolio K, Checler F.
    J Biol Chem; 2003 Apr 04; 278(14):12064-9. PubMed ID: 12556443
    [Abstract] [Full Text] [Related]

  • 8. Autoproteolytic activation of pro-caspases by oligomerization.
    Yang X, Chang HY, Baltimore D.
    Mol Cell; 1998 Jan 04; 1(2):319-25. PubMed ID: 9659928
    [Abstract] [Full Text] [Related]

  • 9. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.
    Matsui H, Hikichi Y, Tsuji I, Yamada T, Shintani Y.
    J Biol Chem; 2002 Dec 20; 277(51):50054-61. PubMed ID: 12393901
    [Abstract] [Full Text] [Related]

  • 10. Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons.
    Araki W, Yuasa K, Takeda S, Takeda K, Shirotani K, Takahashi K, Tabira T.
    J Neurochem; 2001 Dec 20; 79(6):1161-8. PubMed ID: 11752057
    [Abstract] [Full Text] [Related]

  • 11. Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.
    Tomita T, Tokuhiro S, Hashimoto T, Aiba K, Saido TC, Maruyama K, Iwatsubo T.
    J Biol Chem; 1998 Aug 14; 273(33):21153-60. PubMed ID: 9694871
    [Abstract] [Full Text] [Related]

  • 12. Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
    van de Craen M, de Jonghe C, van den Brande I, Declercq W, van Gassen G, van Criekinge W, Vanderhoeven I, Fiers W, van Broeckhoven C, Hendriks L, Vandenabeele P.
    FEBS Lett; 1999 Feb 19; 445(1):149-54. PubMed ID: 10069390
    [Abstract] [Full Text] [Related]

  • 13. Dissociation of apoptosis and activation of IL-1beta-converting enzyme/Ced-3 proteases by ALG-2 and the truncated Alzheimer's gene ALG-3.
    Lacanà E, Ganjei JK, Vito P, D'Adamio L.
    J Immunol; 1997 Jun 01; 158(11):5129-35. PubMed ID: 9164928
    [Abstract] [Full Text] [Related]

  • 14. Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.
    Weidemann A, Paliga K, Dürrwang U, Reinhard FB, Schuckert O, Evin G, Masters CL.
    J Biol Chem; 1999 Feb 26; 274(9):5823-9. PubMed ID: 10026204
    [Abstract] [Full Text] [Related]

  • 15. Overexpression of wild-type presenilin 2 or its familial Alzheimer's disease-associated mutant does not induce or increase susceptibility to apoptosis in different cell lines.
    Gamliel A, Teicher C, Hartmann T, Beyreuther K, Stein R.
    Neuroscience; 2003 Feb 26; 117(1):19-28. PubMed ID: 12605888
    [Abstract] [Full Text] [Related]

  • 16. Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death.
    Passer BJ, Pellegrini L, Vito P, Ganjei JK, D'Adamio L.
    J Biol Chem; 1999 Aug 20; 274(34):24007-13. PubMed ID: 10446169
    [Abstract] [Full Text] [Related]

  • 17. Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor.
    Beyaert R, Kidd VJ, Cornelis S, Van de Craen M, Denecker G, Lahti JM, Gururajan R, Vandenabeele P, Fiers W.
    J Biol Chem; 1997 May 02; 272(18):11694-7. PubMed ID: 9115219
    [Abstract] [Full Text] [Related]

  • 18. Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells.
    Nyormoi O, Wang Z, Doan D, Ruiz M, McConkey D, Bar-Eli M.
    Mol Cell Biol; 2001 Aug 02; 21(15):4856-67. PubMed ID: 11438643
    [Abstract] [Full Text] [Related]

  • 19. Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.
    Walter J, Schindzielorz A, Grünberg J, Haass C.
    Proc Natl Acad Sci U S A; 1999 Feb 16; 96(4):1391-6. PubMed ID: 9990034
    [Abstract] [Full Text] [Related]

  • 20. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis.
    Caulín C, Salvesen GS, Oshima RG.
    J Cell Biol; 1997 Sep 22; 138(6):1379-94. PubMed ID: 9298992
    [Abstract] [Full Text] [Related]

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