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Journal Abstract Search

137 related items for PubMed ID: 9354240

  • 1. Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): an effective inhibitor of glycinamide ribonucleotide transformylase.
    Boger DL, Haynes NE, Warren MS, Ramcharan J, Marolewski AE, Kitos PA, Benkovic SJ.
    Bioorg Med Chem; 1997 Sep; 5(9):1847-52. PubMed ID: 9354240
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  • 3. Functionalized analogues of 5,8,10-trideazafolate: development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase.
    Boger DL, Haynes NE, Warren MS, Ramcharan J, Kitos PA, Benkovic SJ.
    Bioorg Med Chem; 1997 Sep; 5(9):1839-46. PubMed ID: 9354239
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  • 6. 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.
    Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4503-9. PubMed ID: 13129586
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  • 7. 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
    Marsilje TH, Labroli MA, Hedrick MP, Jin Q, Desharnais J, Baker SJ, Gooljarsingh LT, Ramcharan J, Tavassoli A, Zhang Y, Wilson IA, Beardsley GP, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2002 Aug 01; 10(8):2739-49. PubMed ID: 12057663
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  • 11. Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.
    Marsilje TH, Hedrick MP, Desharnais J, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4487-501. PubMed ID: 13129585
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  • 13. Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase.
    Boger DL, Labroli MA, Marsilje TH, Jin Q, Hedrick MP, Baker SJ, Shim JH, Benkovic SJ.
    Bioorg Med Chem; 2000 May 01; 8(5):1075-86. PubMed ID: 10882019
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  • 14. Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
    Desharnais J, Hwang I, Zhang Y, Tavassoli A, Baboval J, Benkovic SJ, Wilson IA, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4511-21. PubMed ID: 13129587
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  • 18. Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase.
    Greasley SE, Marsilje TH, Cai H, Baker S, Benkovic SJ, Boger DL, Wilson IA.
    Biochemistry; 2001 Nov 13; 40(45):13538-47. PubMed ID: 11695901
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  • 19. Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis.
    Wall M, Shim JH, Benkovic SJ.
    Biochemistry; 2000 Sep 19; 39(37):11303-11. PubMed ID: 10985775
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  • 20. On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.
    Smith GK, Mueller WT, Benkovic PA, Benkovic SJ.
    Biochemistry; 1981 Mar 03; 20(5):1241-5. PubMed ID: 7225325
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