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144 related items for PubMed ID: 9356318

  • 1. Determination of parameters responsible for pharmacokinetic behavior of TCDD in female Sprague-Dawley rats.
    Wang X, Santostefano MJ, Evans MV, Richardson VM, Diliberto JJ, Birnbaum LS.
    Toxicol Appl Pharmacol; 1997 Nov; 147(1):151-68. PubMed ID: 9356318
    [Abstract] [Full Text] [Related]

  • 2. A pharmacodynamic analysis of TCDD-induced cytochrome P450 gene expression in multiple tissues: dose- and time-dependent effects.
    Santostefano MJ, Wang X, Richardson VM, Ross DG, DeVito MJ, Birnbaum LS.
    Toxicol Appl Pharmacol; 1998 Aug; 151(2):294-310. PubMed ID: 9707506
    [Abstract] [Full Text] [Related]

  • 3. A physiological pharmacokinetic description of the tissue distribution and enzyme-inducing properties of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat.
    Leung HW, Paustenbach DJ, Murray FJ, Andersen ME.
    Toxicol Appl Pharmacol; 1990 May; 103(3):399-410. PubMed ID: 2160135
    [Abstract] [Full Text] [Related]

  • 4. Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.
    Emond C, Birnbaum LS, DeVito MJ.
    Environ Health Perspect; 2006 Sep; 114(9):1394-400. PubMed ID: 16966094
    [Abstract] [Full Text] [Related]

  • 5. Sensitivity analysis of a physiological model for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): assessing the impact of specific model parameters on sequestration in liver and fat in the rat.
    Evans MV, Andersen ME.
    Toxicol Sci; 2000 Mar; 54(1):71-80. PubMed ID: 10746933
    [Abstract] [Full Text] [Related]

  • 6. Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo-p-dioxin evaluated with a multicompartment geometric model of hepatic zonation.
    Andersen ME, Birnbaum LS, Barton HA, Eklund CR.
    Toxicol Appl Pharmacol; 1997 May; 144(1):145-55. PubMed ID: 9169078
    [Abstract] [Full Text] [Related]

  • 7. Dose-response relationships of tissue distribution and induction of CYP1A1 and CYP1A2 enzymatic activities following acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice.
    Diliberto JJ, Akubue PI, Luebke RW, Birnbaum LS.
    Toxicol Appl Pharmacol; 1995 Feb; 130(2):197-208. PubMed ID: 7871533
    [Abstract] [Full Text] [Related]

  • 8. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Walker NJ, Portier CJ, Lax SF, Crofts FG, Li Y, Lucier GW, Sutter TR.
    Toxicol Appl Pharmacol; 1999 Feb 01; 154(3):279-86. PubMed ID: 9931287
    [Abstract] [Full Text] [Related]

  • 9. Extrapolation of a PBPK model for dioxins across dosage regimen, gender, strain, and species.
    Wang X, Santostefano MJ, DeVito MJ, Birnbaum LS.
    Toxicol Sci; 2000 Jul 01; 56(1):49-60. PubMed ID: 10869453
    [Abstract] [Full Text] [Related]

  • 10. A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: tissue distribution and CYP1A induction.
    Kedderis LB, Mills JJ, Andersen ME, Birnbaum LS.
    Toxicol Appl Pharmacol; 1993 Jul 01; 121(1):87-98. PubMed ID: 8337704
    [Abstract] [Full Text] [Related]

  • 11. A mechanistic model of effects of dioxin on thyroid hormones in the rat.
    Kohn MC, Sewall CH, Lucier GW, Portier CJ.
    Toxicol Appl Pharmacol; 1996 Jan 01; 136(1):29-48. PubMed ID: 8560478
    [Abstract] [Full Text] [Related]

  • 12. Validation of precision-cut liver slices in dynamic organ culture as an in vitro model for studying CYP1A1 and CYP1A2 induction.
    Drahushuk AT, McGarrigle BP, Tai HL, Kitareewan S, Goldstein JA, Olson JR.
    Toxicol Appl Pharmacol; 1996 Oct 01; 140(2):393-403. PubMed ID: 8887457
    [Abstract] [Full Text] [Related]

  • 13. Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung.
    Pollenz RS, Santostefano MJ, Klett E, Richardson VM, Necela B, Birnbaum LS.
    Toxicol Sci; 1998 Apr 01; 42(2):117-28. PubMed ID: 9579024
    [Abstract] [Full Text] [Related]

  • 14. Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver.
    Tritscher AM, Goldstein JA, Portier CJ, McCoy Z, Clark GC, Lucier GW.
    Cancer Res; 1992 Jun 15; 52(12):3436-42. PubMed ID: 1596902
    [Abstract] [Full Text] [Related]

  • 15. Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (Cas No. 31508-00-6) in female Harlan Sprague-Dawley rats (gavage studies).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2006 Nov 15; (531):1-218. PubMed ID: 17342196
    [Abstract] [Full Text] [Related]

  • 16. A mechanistic model of effects of dioxin on gene expression in the rat liver.
    Kohn MC, Lucier GW, Clark GC, Sewall C, Tritscher AM, Portier CJ.
    Toxicol Appl Pharmacol; 1993 May 15; 120(1):138-54. PubMed ID: 8511776
    [Abstract] [Full Text] [Related]

  • 17. Time- and concentration-dependent induction of CYP1A1 and CYP1A2 in precision-cut rat liver slices incubated in dynamic organ culture in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Drahushuk AT, McGarrigle BP, Slezak BP, Stegeman JJ, Olson JR.
    Toxicol Appl Pharmacol; 1999 Mar 01; 155(2):127-38. PubMed ID: 10053167
    [Abstract] [Full Text] [Related]

  • 18. Toxicology and carcinogenesis studies of a mixture of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) (Cas No. 1746-01-6), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) (Cas No. 57117-31-4), and 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) in female Harlan Sprague-Dawley rats (gavage studies).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2006 Sep 01; (526):1-180. PubMed ID: 17342195
    [Abstract] [Full Text] [Related]

  • 19. NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2006 May 01; (529):4-168. PubMed ID: 16835634
    [Abstract] [Full Text] [Related]

  • 20. Differential time-course and dose-response relationships of TCDD-induced CYP1B1, CYP1A1, and CYP1A2 proteins in rats.
    Santostefano MJ, Ross DG, Savas U, Jefcoate CR, Birnbaum LS.
    Biochem Biophys Res Commun; 1997 Apr 07; 233(1):20-4. PubMed ID: 9144388
    [Abstract] [Full Text] [Related]

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