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Journal Abstract Search


126 related items for PubMed ID: 9360704

  • 1. dUTP pyrophosphatase as a potential target for chemotherapeutic drug development.
    McIntosh EM, Haynes RH.
    Acta Biochim Pol; 1997; 44(2):159-71. PubMed ID: 9360704
    [Abstract] [Full Text] [Related]

  • 2. Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target.
    Harris JM, McIntosh EM, Muscat GE.
    J Mol Biol; 1999 Apr 30; 288(2):275-87. PubMed ID: 10329142
    [Abstract] [Full Text] [Related]

  • 3. Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition.
    Koehler SE, Ladner RD.
    Mol Pharmacol; 2004 Sep 30; 66(3):620-6. PubMed ID: 15322254
    [Abstract] [Full Text] [Related]

  • 4. HIV and human endogenous retroviruses: an hypothesis with therapeutic implications.
    McIntosh EM, Haynes RH.
    Acta Biochim Pol; 1996 Sep 30; 43(4):583-92. PubMed ID: 9104494
    [Abstract] [Full Text] [Related]

  • 5. The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition.
    Webley SD, Welsh SJ, Jackman AL, Aherne GW.
    Br J Cancer; 2001 Aug 03; 85(3):446-52. PubMed ID: 11487279
    [Abstract] [Full Text] [Related]

  • 6. Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases.
    Quesada-Soriano I, Casas-Solvas JM, Recio E, Ruiz-Pérez LM, Vargas-Berenguel A, González-Pacanowska D, García-Fuentes L.
    Biochimie; 2010 Feb 03; 92(2):178-86. PubMed ID: 19879316
    [Abstract] [Full Text] [Related]

  • 7. dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae.
    Tinkelenberg BA, Hansbury MJ, Ladner RD.
    Cancer Res; 2002 Sep 01; 62(17):4909-15. PubMed ID: 12208740
    [Abstract] [Full Text] [Related]

  • 8. dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer.
    Ladner RD, Lynch FJ, Groshen S, Xiong YP, Sherrod A, Caradonna SJ, Stoehlmacher J, Lenz HJ.
    Cancer Res; 2000 Jul 01; 60(13):3493-503. PubMed ID: 10910061
    [Abstract] [Full Text] [Related]

  • 9. The role of dUTPase and uracil-DNA repair in cancer chemotherapy.
    Ladner RD.
    Curr Protein Pept Sci; 2001 Dec 01; 2(4):361-70. PubMed ID: 12374095
    [Abstract] [Full Text] [Related]

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  • 12. Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitor ZD9331.
    Webley SD, Hardcastle A, Ladner RD, Jackman AL, Aherne GW.
    Br J Cancer; 2000 Sep 01; 83(6):792-9. PubMed ID: 10952785
    [Abstract] [Full Text] [Related]

  • 13. An isotopic assay of dUTPase activity based on coupling with thymidylate synthase.
    Gołos B, Rode W.
    Acta Biochim Pol; 1999 Sep 01; 46(3):837-40. PubMed ID: 10698291
    [Abstract] [Full Text] [Related]

  • 14. Kinetic properties and stereospecificity of the monomeric dUTPase from herpes simplex virus type 1.
    Bergman AC, Nyman PO, Larsson G.
    FEBS Lett; 1998 Dec 18; 441(2):327-30. PubMed ID: 9883909
    [Abstract] [Full Text] [Related]

  • 15. Effects of mercury (II) compounds on the activity of dUTPases from various sources.
    Williams MV.
    Mol Pharmacol; 1986 Mar 18; 29(3):288-92. PubMed ID: 3005836
    [Abstract] [Full Text] [Related]

  • 16. Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
    Varga B, Barabás O, Takács E, Nagy N, Nagy P, Vértessy BG.
    Biochem Biophys Res Commun; 2008 Aug 15; 373(1):8-13. PubMed ID: 18519027
    [Abstract] [Full Text] [Related]

  • 17. Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme.
    McIntosh EM, Ager DD, Gadsden MH, Haynes RH.
    Proc Natl Acad Sci U S A; 1992 Sep 01; 89(17):8020-4. PubMed ID: 1325640
    [Abstract] [Full Text] [Related]

  • 18. A tyrosine kinase inhibitor, beta-hydroxyisovalerylshikonin, induced apoptosis in human lung cancer DMS114 cells through reduction of dUTP nucleotidohydrolase activity.
    Kajimoto S, Horie M, Manabe H, Masuda Y, Shibayama-Imazu T, Nakajo S, Gong XF, Obama T, Itabe H, Nakaya K.
    Biochim Biophys Acta; 2008 Jan 01; 1782(1):41-50. PubMed ID: 18078828
    [Abstract] [Full Text] [Related]

  • 19. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases.
    Moroz OV, Harkiolaki M, Galperin MY, Vagin AA, González-Pacanowska D, Wilson KS.
    J Mol Biol; 2004 Oct 01; 342(5):1583-97. PubMed ID: 15364583
    [Abstract] [Full Text] [Related]

  • 20. Structures of vaccinia virus dUTPase and its nucleotide complexes.
    Samal A, Schormann N, Cook WJ, DeLucas LJ, Chattopadhyay D.
    Acta Crystallogr D Biol Crystallogr; 2007 May 01; 63(Pt 5):571-80. PubMed ID: 17452782
    [Abstract] [Full Text] [Related]


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