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245 related items for PubMed ID: 9367523

  • 1. Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1.
    Savas U, Carstens CP, Jefcoate CR.
    Arch Biochem Biophys; 1997 Nov 15; 347(2):181-92. PubMed ID: 9367523
    [Abstract] [Full Text] [Related]

  • 2. Mouse endometrium stromal cells express a polycyclic aromatic hydrocarbon-inducible cytochrome P450 that closely resembles the novel P450 in mouse embryo fibroblasts (P450EF).
    Savas U, Christou M, Jefcoate CR.
    Carcinogenesis; 1993 Oct 15; 14(10):2013-8. PubMed ID: 8222047
    [Abstract] [Full Text] [Related]

  • 3. Characterization of CYP1B1 and CYP1A1 expression in human mammary epithelial cells: role of the aryl hydrocarbon receptor in polycyclic aromatic hydrocarbon metabolism.
    Larsen MC, Angus WG, Brake PB, Eltom SE, Sukow KA, Jefcoate CR.
    Cancer Res; 1998 Jun 01; 58(11):2366-74. PubMed ID: 9622076
    [Abstract] [Full Text] [Related]

  • 4. Cytochromes CYP1A1 and CYP1B1 in the rat mammary gland: cell-specific expression and regulation by polycyclic aromatic hydrocarbons and hormones.
    Christou M, Savas U, Schroeder S, Shen X, Thompson T, Gould MN, Jefcoate CR.
    Mol Cell Endocrinol; 1995 Nov 30; 115(1):41-50. PubMed ID: 8674863
    [Abstract] [Full Text] [Related]

  • 5. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
    Shimada T, Oda Y, Gillam EM, Guengerich FP, Inoue K.
    Drug Metab Dispos; 2001 Sep 30; 29(9):1176-82. PubMed ID: 11502724
    [Abstract] [Full Text] [Related]

  • 6. Metabolism-based polycyclic aromatic acetylene inhibition of CYP1B1 in 10T1/2 cells potentiates aryl hydrocarbon receptor activity.
    Alexander DL, Zhang L, Foroozesh M, Alworth WL, Jefcoate CR.
    Toxicol Appl Pharmacol; 1999 Dec 01; 161(2):123-39. PubMed ID: 10581206
    [Abstract] [Full Text] [Related]

  • 7. The role of polycyclic aromatic hydrocarbon metabolism in dimethylbenz[a]anthracene-induced pre-B lymphocyte apoptosis.
    Mann KK, Matulka RA, Hahn ME, Trombino AF, Lawrence BP, Kerkvliet NI, Sherr DH.
    Toxicol Appl Pharmacol; 1999 Nov 15; 161(1):10-22. PubMed ID: 10558919
    [Abstract] [Full Text] [Related]

  • 8. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.
    Galván N, Teske DE, Zhou G, Moorthy B, MacWilliams PS, Czuprynski CJ, Jefcoate CR.
    Toxicol Appl Pharmacol; 2005 Feb 01; 202(3):244-57. PubMed ID: 15667830
    [Abstract] [Full Text] [Related]

  • 9. 7,12-Dimethylbenz[a]anthracene inhibition of steroid production in MA-10 mouse Leydig tumor cells is not directly linked to induction of CYP1B1.
    Mandal PK, McDaniel LR, Prough RA, Clark BJ.
    Toxicol Appl Pharmacol; 2001 Sep 15; 175(3):200-8. PubMed ID: 11559018
    [Abstract] [Full Text] [Related]

  • 10. Bone marrow stromal cells constitutively express high levels of cytochrome P4501B1 that metabolize 7,12-dimethylbenz[a]anthracene.
    Heidel SM, Czuprynski CJ, Jefcoate CR.
    Mol Pharmacol; 1998 Dec 15; 54(6):1000-6. PubMed ID: 9855628
    [Abstract] [Full Text] [Related]

  • 11. Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells).
    Ikegwuonu FI, Jefcoate CR.
    Mol Cell Biochem; 1999 Aug 15; 198(1-2):89-100. PubMed ID: 10497882
    [Abstract] [Full Text] [Related]

  • 12. Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells.
    Alexander DL, Eltom SE, Jefcoate CR.
    Cancer Res; 1997 Oct 15; 57(20):4498-506. PubMed ID: 9377560
    [Abstract] [Full Text] [Related]

  • 13. Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation.
    Bhattacharyya KK, Brake PB, Eltom SE, Otto SA, Jefcoate CR.
    J Biol Chem; 1995 May 12; 270(19):11595-602. PubMed ID: 7744798
    [Abstract] [Full Text] [Related]

  • 14. Specificity of 17beta-oestradiol and benzo[a]pyrene oxidation by polymorphic human cytochrome P4501B1 variants substituted at residues 48, 119 and 432.
    Shimada T, Watanabe J, Inoue K, Guengerich FP, Gillam EM.
    Xenobiotica; 2001 Mar 12; 31(3):163-76. PubMed ID: 11465393
    [Abstract] [Full Text] [Related]

  • 15. A novel adrenocorticotropin-inducible cytochrome P450 from rat adrenal microsomes catalyzes polycyclic aromatic hydrocarbon metabolism.
    Otto S, Marcus C, Pidgeon C, Jefcoate C.
    Endocrinology; 1991 Aug 12; 129(2):970-82. PubMed ID: 1649753
    [Abstract] [Full Text] [Related]

  • 16. Binding and metabolism of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene by seven purified forms of cytochrome P-450.
    Wilson NM, Christou M, Turner CR, Wrighton SA, Jefcoate CR.
    Carcinogenesis; 1984 Nov 12; 5(11):1475-83. PubMed ID: 6435901
    [Abstract] [Full Text] [Related]

  • 17. Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
    Kleiner HE, Vulimiri SV, Reed MJ, Uberecken A, DiGiovanni J.
    Chem Res Toxicol; 2002 Feb 12; 15(2):226-35. PubMed ID: 11849049
    [Abstract] [Full Text] [Related]

  • 18. Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status.
    Angus WG, Larsen MC, Jefcoate CR.
    Carcinogenesis; 1999 Jun 12; 20(6):947-55. PubMed ID: 10357772
    [Abstract] [Full Text] [Related]

  • 19. Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase.
    Shou M, Gonzalez FJ, Gelboin HV.
    Biochemistry; 1996 Dec 10; 35(49):15807-13. PubMed ID: 8961944
    [Abstract] [Full Text] [Related]

  • 20. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
    Shou M, Korzekwa KR, Krausz KW, Buters JT, Grogan J, Goldfarb I, Hardwick JP, Gonzalez FJ, Gelboin HV.
    Mol Carcinog; 1996 Dec 10; 17(4):241-9. PubMed ID: 8989918
    [Abstract] [Full Text] [Related]

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