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628 related items for PubMed ID: 9367528

  • 1. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
    Wu K, Knox R, Sun XZ, Joseph P, Jaiswal AK, Zhang D, Deng PS, Chen S.
    Arch Biochem Biophys; 1997 Nov 15; 347(2):221-8. PubMed ID: 9367528
    [Abstract] [Full Text] [Related]

  • 2. Catalytic properties of NAD(P)H:quinone acceptor oxidoreductase: study involving mouse, rat, human, and mouse-rat chimeric enzymes.
    Chen S, Knox R, Lewis AD, Friedlos F, Workman P, Deng PS, Fung M, Ebenstein D, Wu K, Tsai TM.
    Mol Pharmacol; 1995 May 15; 47(5):934-9. PubMed ID: 7746280
    [Abstract] [Full Text] [Related]

  • 3. Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2: a novel co-substrate-mediated antitumor prodrug therapy.
    Knox RJ, Jenkins TC, Hobbs SM, Chen S, Melton RG, Burke PJ.
    Cancer Res; 2000 Aug 01; 60(15):4179-86. PubMed ID: 10945627
    [Abstract] [Full Text] [Related]

  • 4. Structure-function studies of DT-diaphorase (NQO1) and NRH: quinone oxidoreductase (NQO2).
    Chen S, Wu K, Knox R.
    Free Radic Biol Med; 2000 Aug 01; 29(3-4):276-84. PubMed ID: 11035256
    [Abstract] [Full Text] [Related]

  • 5. NAD(P)H:quinone oxidoreductase 1 and nrh:quinone oxidoreductase 2 activity and expression in bladder and ovarian cancer and lower NRH:quinone oxidoreductase 2 activity associated with an NQO2 exon 3 single-nucleotide polymorphism.
    Jamieson D, Wilson K, Pridgeon S, Margetts JP, Edmondson RJ, Leung HY, Knox R, Boddy AV.
    Clin Cancer Res; 2007 Mar 01; 13(5):1584-90. PubMed ID: 17332305
    [Abstract] [Full Text] [Related]

  • 6. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 01; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 7. Advances in research on DT-diaphorase--catalytic properties, regulation of activity and significance in the detoxication of foreign compounds.
    Horie S.
    Kitasato Arch Exp Med; 1990 Apr 01; 63(1):11-30. PubMed ID: 2125671
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of NAD(P)H:quinone acceptor oxidoreductase by flavones: a structure-activity study.
    Chen S, Hwang J, Deng PS.
    Arch Biochem Biophys; 1993 Apr 01; 302(1):72-7. PubMed ID: 8470908
    [Abstract] [Full Text] [Related]

  • 9. Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling.
    Chen S, Wu K, Zhang D, Sherman M, Knox R, Yang CS.
    Mol Pharmacol; 1999 Aug 01; 56(2):272-8. PubMed ID: 10419545
    [Abstract] [Full Text] [Related]

  • 10. Demonstration of the activation of prodrug CB 1954 using human DT-diaphorase mutant Q104Y-transfected MDA-MB-231 cells and mouse xenograft model.
    Wu K, Eng E, Knox R, Chen S.
    Arch Biochem Biophys; 2001 Jan 01; 385(1):203-8. PubMed ID: 11361019
    [Abstract] [Full Text] [Related]

  • 11. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Nov 15; 50(22):7293-300. PubMed ID: 2121335
    [Abstract] [Full Text] [Related]

  • 12. Interaction of flavones and their bromoacetyl derivatives with NAD(P)H:quinone acceptor oxidoreductase.
    Chen S, Deng PS, Swiderek K, Li M, Chan SI.
    Mol Pharmacol; 1995 Feb 15; 47(2):419-24. PubMed ID: 7870053
    [Abstract] [Full Text] [Related]

  • 13. Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones.
    Gaikwad NW, Yang L, Rogan EG, Cavalieri EL.
    Free Radic Biol Med; 2009 Jan 15; 46(2):253-62. PubMed ID: 18996184
    [Abstract] [Full Text] [Related]

  • 14. Identification of novel reduced pyridinium derivatives as synthetic co-factors for the enzyme DT diaphorase (NAD(P)H dehydrogenase (quinone), EC 1.6.99.2).
    Friedlos F, Jarman M, Davies LC, Boland MP, Knox RJ.
    Biochem Pharmacol; 1992 Jul 07; 44(1):25-31. PubMed ID: 1385952
    [Abstract] [Full Text] [Related]

  • 15. Roles of histidine-194, aspartate-163, and a glycine-rich sequence of NAD(P)H:quinone oxidoreductase in the interaction with nicotinamide coenzymes.
    Cui K, Ma Q, Lu AY, Yang CS.
    Arch Biochem Biophys; 1995 Nov 10; 323(2):265-73. PubMed ID: 7487087
    [Abstract] [Full Text] [Related]

  • 16. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.
    den Braver-Sewradj SP, den Braver MW, Toorneman RM, van Leeuwen S, Zhang Y, Dekker SJ, Vermeulen NPE, Commandeur JNM, Vos JC.
    Chem Res Toxicol; 2018 Feb 19; 31(2):116-126. PubMed ID: 29281794
    [Abstract] [Full Text] [Related]

  • 17. Role of Nad(P)h: quinone oxidoreductase in the regulation of intracellular redox state.
    Mohora M.
    Rom J Intern Med; 2018 Feb 19; 38-39():33-50. PubMed ID: 15529570
    [Abstract] [Full Text] [Related]

  • 18. Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity.
    Friedlos F, Biggs PJ, Abrahamson JA, Knox RJ.
    Biochem Pharmacol; 1992 Nov 03; 44(9):1739-43. PubMed ID: 1449531
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of rat liver NAD(P)H:quinone acceptor oxidoreductase (DT-diaphorase) by flavonoids isolated from the Chinese herb scutellariae radix (Huang Qin).
    Liu XF, Liu ML, Iyanagi T, Legesse K, Lee TD, Chen SA.
    Mol Pharmacol; 1990 Jun 03; 37(6):911-5. PubMed ID: 1694261
    [Abstract] [Full Text] [Related]

  • 20. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

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