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Journal Abstract Search

391 related items for PubMed ID: 9369431

  • 1. Mutant AF-2 domain of PML-RARalpha in retinoic acid-resistant NB4 cells: differentiation induced by RA is triggered directly through PML-RARalpha and its down-regulation in acute promyelocytic leukemia.
    Kitamura K, Kiyoi H, Yoshida H, Saito H, Ohno R, Naoe T.
    Leukemia; 1997 Nov; 11(11):1950-6. PubMed ID: 9369431
    [Abstract] [Full Text] [Related]

  • 2. Differential changes of retinoid-X-receptor (RXR alpha) and its RAR alpha and PML-RAR alpha partners induced by retinoic acid and cAMP distinguish maturation sensitive and resistant t(15;17) promyelocytic leukemia NB4 cells.
    Duprez E, Lillehaug JR, Gaub MP, Lanotte M.
    Oncogene; 1996 Jun 06; 12(11):2443-50. PubMed ID: 8649786
    [Abstract] [Full Text] [Related]

  • 3. cAMP signalling is decisive for recovery of nuclear bodies (PODs) during maturation of RA-resistant t(15;17) promyelocytic leukemia NB4 cells expressing PML-RAR alpha.
    Duprez E, Lillehaug JR, Naoe T, Lanotte M.
    Oncogene; 1996 Jun 06; 12(11):2451-9. PubMed ID: 8649787
    [Abstract] [Full Text] [Related]

  • 4. Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.
    Benedetti L, Grignani F, Scicchitano BM, Jetten AM, Diverio D, Lo Coco F, Avvisati G, Gambacorti-Passerini C, Adamo S, Levin AA, Pelicci PG, Nervi C.
    Blood; 1996 Mar 01; 87(5):1939-50. PubMed ID: 8634442
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  • 6. UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia.
    Kitareewan S, Pitha-Rowe I, Sekula D, Lowrey CH, Nemeth MJ, Golub TR, Freemantle SJ, Dmitrovsky E.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3806-11. PubMed ID: 11891284
    [Abstract] [Full Text] [Related]

  • 7. Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein.
    Nervi C, Ferrara FF, Fanelli M, Rippo MR, Tomassini B, Ferrucci PF, Ruthardt M, Gelmetti V, Gambacorti-Passerini C, Diverio D, Grignani F, Pelicci PG, Testi R.
    Blood; 1998 Oct 01; 92(7):2244-51. PubMed ID: 9746761
    [Abstract] [Full Text] [Related]

  • 8. A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation.
    Shao W, Benedetti L, Lamph WW, Nervi C, Miller WH.
    Blood; 1997 Jun 15; 89(12):4282-9. PubMed ID: 9192750
    [Abstract] [Full Text] [Related]

  • 9. Leukemic cellular retinoic acid resistance and missense mutations in the PML-RARalpha fusion gene after relapse of acute promyelocytic leukemia from treatment with all-trans retinoic acid and intensive chemotherapy.
    Ding W, Li YP, Nobile LM, Grills G, Carrera I, Paietta E, Tallman MS, Wiernik PH, Gallagher RE.
    Blood; 1998 Aug 15; 92(4):1172-83. PubMed ID: 9694705
    [Abstract] [Full Text] [Related]

  • 10. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.
    Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.
    Nature; 1998 Feb 19; 391(6669):815-8. PubMed ID: 9486655
    [Abstract] [Full Text] [Related]

  • 11. Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells.
    Nason-Burchenal K, Allopenna J, Bègue A, Stéhelin D, Dmitrovsky E, Martin P.
    Blood; 1998 Sep 01; 92(5):1758-67. PubMed ID: 9716606
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  • 13. Constitutive degradation of PML/RARalpha through the proteasome pathway mediates retinoic acid resistance.
    Fanelli M, Minucci S, Gelmetti V, Nervi C, Gambacorti-Passerini C, Pelicci PG.
    Blood; 1999 Mar 01; 93(5):1477-81. PubMed ID: 10029573
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  • 15. Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line.
    Nason-Burchenal K, Gandini D, Botto M, Allopenna J, Seale JR, Cross NC, Goldman JM, Dmitrovsky E, Pandolfi PP.
    Blood; 1996 Nov 15; 88(10):3926-36. PubMed ID: 8916959
    [Abstract] [Full Text] [Related]

  • 16. Response to histone deacetylase inhibition of novel PML/RARalpha mutants detected in retinoic acid-resistant APL cells.
    Côté S, Rosenauer A, Bianchini A, Seiter K, Vandewiele J, Nervi C, Miller WH.
    Blood; 2002 Oct 01; 100(7):2586-96. PubMed ID: 12239173
    [Abstract] [Full Text] [Related]

  • 17. Mutations in the E-domain of RAR portion of the PML/RAR chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia.
    Imaizumi M, Suzuki H, Yoshinari M, Sato A, Saito T, Sugawara A, Tsuchiya S, Hatae Y, Fujimoto T, Kakizuka A, Konno T, Iinuma K.
    Blood; 1998 Jul 15; 92(2):374-82. PubMed ID: 9657734
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  • 19. A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities.
    Duprez E, Benoit G, Flexor M, Lillehaug JR, Lanotte M.
    Leukemia; 2000 Feb 15; 14(2):255-61. PubMed ID: 10673742
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