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Journal Abstract Search


148 related items for PubMed ID: 9371085

  • 1. Tritrichomonas foetus: a strategy for structure-based inhibitor design of a protozoan inosine-5'-monophosphate dehydrogenase.
    Luecke H, Prosise GL, Whitby FG.
    Exp Parasitol; 1997 Nov; 87(3):203-11. PubMed ID: 9371085
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  • 2. Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex.
    Whitby FG, Luecke H, Kuhn P, Somoza JR, Huete-Perez JA, Phillips JD, Hill CP, Fletterick RJ, Wang CC.
    Biochemistry; 1997 Sep 02; 36(35):10666-74. PubMed ID: 9271497
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  • 3. Crystal structure of Tritrichomonas foetus inosine monophosphate dehydrogenase in complex with the inhibitor ribavirin monophosphate reveals a catalysis-dependent ion-binding site.
    Prosise GL, Wu JZ, Luecke H.
    J Biol Chem; 2002 Dec 27; 277(52):50654-9. PubMed ID: 12235158
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  • 4. Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis.
    Gan L, Petsko GA, Hedstrom L.
    Biochemistry; 2002 Nov 05; 41(44):13309-17. PubMed ID: 12403633
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  • 8. Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6.
    McMillan FM, Cahoon M, White A, Hedstrom L, Petsko GA, Ringe D.
    Biochemistry; 2000 Apr 18; 39(15):4533-42. PubMed ID: 10758003
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  • 10. Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Prosise GL, Luecke H.
    J Mol Biol; 2003 Feb 14; 326(2):517-27. PubMed ID: 12559919
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  • 12. IMP dehydrogenase : structural aspects of inhibitor binding.
    Goldstein BM, Colby TD.
    Curr Med Chem; 1999 Jul 14; 6(7):519-36. PubMed ID: 10390598
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  • 13. Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.
    Wang W, Papov VV, Minakawa N, Matsuda A, Biemann K, Hedstrom L.
    Biochemistry; 1996 Jan 09; 35(1):95-101. PubMed ID: 8555204
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  • 14. The conformation of NADH bound to inosine 5'-monophosphate dehydrogenase determined by transferred nuclear Overhauser effect spectroscopy.
    Schalk-Hihi C, Zhang YZ, Markham GD.
    Biochemistry; 1998 May 19; 37(20):7608-16. PubMed ID: 9585576
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  • 16. Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid.
    Digits JA, Hedstrom L.
    Biochemistry; 1999 Nov 16; 38(46):15388-97. PubMed ID: 10563825
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  • 17. Mycophenolic acid and thiazole adenine dinucleotide inhibition of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: implications on enzyme mechanism.
    Hedstrom L, Wang CC.
    Biochemistry; 1990 Jan 30; 29(4):849-54. PubMed ID: 1971185
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  • 19. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus.
    Somoza JR, Chin MS, Focia PJ, Wang CC, Fletterick RJ.
    Biochemistry; 1996 Jun 04; 35(22):7032-40. PubMed ID: 8679528
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  • 20. The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase.
    Gan L, Seyedsayamdost MR, Shuto S, Matsuda A, Petsko GA, Hedstrom L.
    Biochemistry; 2003 Feb 04; 42(4):857-63. PubMed ID: 12549902
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