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133 related items for PubMed ID: 9377103

  • 1. Potent and subtype-selective CCK-B/gastrin receptor antagonists: 2,4-dioxo-1,5-benzodiazepines with a plane of symmetry.
    Hagishita S, Seno K, Kamata S, Haga N, Ishihara Y, Ishikawa M, Shimamura M.
    Bioorg Med Chem; 1997 Jul; 5(7):1433-46. PubMed ID: 9377103
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
    Nishida A, Miyata K, Tsutsumi R, Yuki H, Akuzawa S, Kobayashi A, Kamato T, Ito H, Yamano M, Katuyama Y.
    J Pharmacol Exp Ther; 1994 May; 269(2):725-31. PubMed ID: 7910212
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and pharmacological properties of ureidomethylcarbamoylphenylketone derivatives. A new potent and subtype-selective nonpeptide CCK-B/gastrin receptor antagonist, S-0509.
    Hagishita S, Murakami Y, Seno K, Kamata S, Haga N, Konoike T, Kanda Y, Kiyama R, Shiota T, Ishihara Y, Ishikawa M, Shimamura M, Abe K, Yoshimura K.
    Bioorg Med Chem; 1997 Aug; 5(8):1695-714. PubMed ID: 9313871
    [Abstract] [Full Text] [Related]

  • 4. Selective non-peptide ligands for an accommodating peptide receptor. Imidazobenzodiazepines as potent cholecystokinin type B receptor antagonists.
    Bock MG, DiPardo RM, Newton RC, Bergman JM, Veber DF, Freedman SB, Smith AJ, Chapman KL, Patel S, Kemp JA.
    Bioorg Med Chem; 1994 Sep; 2(9):987-98. PubMed ID: 7712133
    [Abstract] [Full Text] [Related]

  • 5. (3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist.
    Semple G, Ryder H, Rooker DP, Batt AR, Kendrick DA, Szelke M, Ohta M, Satoh M, Nishida A, Akuzawa S, Miyata K.
    J Med Chem; 1997 Jan 31; 40(3):331-41. PubMed ID: 9022799
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.
    Ursini A, Capelli AM, Carr RA, Cassarà P, Corsi M, Curcuruto O, Curotto G, Dal Cin M, Davalli S, Donati D, Feriani A, Finch H, Finizia G, Gaviraghi G, Marien M, Pentassuglia G, Polinelli S, Ratti E, Reggiani AM, Tarzia G, Tedesco G, Tranquillini ME, Trist DG, Van Amsterdam FT.
    J Med Chem; 2000 Oct 05; 43(20):3596-613. PubMed ID: 11020274
    [Abstract] [Full Text] [Related]

  • 7. Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo.
    Patel S, Smith AJ, Chapman KL, Fletcher AE, Kemp JA, Marshall GR, Hargreaves RJ, Ryecroft W, Iversen LL, Iversen SD.
    Mol Pharmacol; 1994 Nov 05; 46(5):943-8. PubMed ID: 7969084
    [Abstract] [Full Text] [Related]

  • 8. Quantitative structure-activity relationship study on some nonpeptidal cholecystokinin antagonists.
    Sinha J, Kurup A, Paleti A, Gupta SP.
    Bioorg Med Chem; 1999 Jun 05; 7(6):1127-30. PubMed ID: 10428383
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of phenoxyacetic acid derivatives as highly potent antagonists of gastrin/cholecystokinin-B receptors. II.
    Takeda Y, Kawagoe K, Yokomizo A, Yokomizo Y, Hosokami T, Shimoto Y, Tabuchi Y, Ogihara Y, Otsubo R, Honda Y, Yokohama S.
    Chem Pharm Bull (Tokyo); 1998 Jun 05; 46(6):951-61. PubMed ID: 9658573
    [Abstract] [Full Text] [Related]

  • 10. Biological activity of analogues of YM022. Novel (3-amino substituted phenyl)urea derivatives of 1,4-benzodiazepin-2-one as gastrin/cholecystokinin-B receptor antagonists.
    Satoh M, Okamoto Y, Koshio H, Ohta M, Nishida A, Akuzawa S, Miyata K, Mase T, Semple G.
    Chem Pharm Bull (Tokyo); 1996 Jul 05; 44(7):1412-4. PubMed ID: 8706146
    [Abstract] [Full Text] [Related]

  • 11. 5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor.
    Castro JL, Broughton HB, Russell MG, Rathbone D, Watt AP, Ball RG, Chapman KL, Patel S, Smith AJ, Marshall GR, Matassa VG.
    J Med Chem; 1997 Aug 01; 40(16):2491-501. PubMed ID: 9258356
    [Abstract] [Full Text] [Related]

  • 12. Peptide/benzodiazepine hybrids as ligands of CCK(A) and CCK(B) receptors.
    Escherich A, Lutz J, Escrieut C, Fourmy D, van Neuren AS, Müller G, Schafferhans A, Klebe G, Moroder L.
    Biopolymers; 1997 Aug 01; 56(2):55-76. PubMed ID: 11592053
    [Abstract] [Full Text] [Related]

  • 13. Relationship between dihedral angles of N1 and C9 substituents in 1,4-benzodiazepines and dual cholecystokinin-A and -B antagonistic activities.
    Tabuchi S, Nakanishi I, Satoh Y.
    Bioorg Med Chem Lett; 1998 Jun 16; 8(12):1449-54. PubMed ID: 9873368
    [Abstract] [Full Text] [Related]

  • 14. YF476 is a new potent and selective gastrin/cholecystokinin-B receptor antagonist in vitro and in vivo.
    Takinami Y, Yuki H, Nishida A, Akuzawa S, Uchida A, Takemoto Y, Ohta M, Satoh M, Semple G, Miyata K.
    Aliment Pharmacol Ther; 1997 Feb 16; 11(1):113-20. PubMed ID: 9042983
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and structure-activity relationships of dual histamine H2 and gastrin receptor antagonists with noncyclic gastrin receptor antagonistic moieties.
    Kawanishi Y, Ishihara S, Kiyama R, Hagishita S, Tsushima T, Ishikawa M, Ishihara Y.
    Bioorg Med Chem; 1997 Jul 16; 5(7):1425-31. PubMed ID: 9377102
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological properties of ureido-acetamides, new potent and selective non-peptide CCKB/gastrin receptor antagonists.
    Bertrand P, Böhme GA, Durieux C, Guyon C, Capet M, Jeantaud B, Boudeau P, Ducos B, Pendley CE, Martin GE.
    Eur J Pharmacol; 1994 Sep 12; 262(3):233-45. PubMed ID: 7813588
    [Abstract] [Full Text] [Related]

  • 17. New 1,4-benzodiazepin-2-one derivatives as gastrin/cholecystokinin-B antagonists.
    Satoh M, Kondoh Y, Okamoto Y, Nishida A, Miyata K, Ohta M, Mase T, Murase K.
    Chem Pharm Bull (Tokyo); 1995 Dec 12; 43(12):2159-67. PubMed ID: 8582018
    [Abstract] [Full Text] [Related]

  • 18. A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260.
    Lotti VJ, Chang RS.
    Eur J Pharmacol; 1989 Mar 21; 162(2):273-80. PubMed ID: 2721567
    [Abstract] [Full Text] [Related]

  • 19. YM022, a potent and selective gastrin/CCK-B receptor antagonist, inhibits peptone meal-induced gastric acid secretion in Heidenhain pouch dogs.
    Yuki H, Nishida A, Miyake A, Ito H, Akuzawa S, Takinami Y, Takemoto Y, Miyata K.
    Dig Dis Sci; 1997 Apr 21; 42(4):707-14. PubMed ID: 9125636
    [Abstract] [Full Text] [Related]

  • 20. 5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists.
    Lowe JA, Hageman DL, Drozda SE, McLean S, Bryce DK, Crawford RT, Zorn S, Morrone J, Bordner J.
    J Med Chem; 1994 Oct 28; 37(22):3789-811. PubMed ID: 7966138
    [Abstract] [Full Text] [Related]

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