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PUBMED FOR HANDHELDS

Journal Abstract Search


320 related items for PubMed ID: 9379450

  • 1. 17-Imidazolyl, pyrazolyl, and isoxazolyl androstene derivatives. Novel steroidal inhibitors of human cytochrome C17,20-lyase (P450(17 alpha).
    Ling YZ, Li JS, Liu Y, Kato K, Klus GT, Brodie A.
    J Med Chem; 1997 Sep 26; 40(20):3297-304. PubMed ID: 9379450
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  • 2. Novel 17-azolyl steroids, potent inhibitors of human cytochrome 17 alpha-hydroxylase-C17,20-lyase (P450(17) alpha): potential agents for the treatment of prostate cancer.
    Njar VC, Kato K, Nnane IP, Grigoryev DN, Long BJ, Brodie AM.
    J Med Chem; 1998 Mar 12; 41(6):902-12. PubMed ID: 9526564
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  • 3. Synthesis and evaluation of pregnane derivatives as inhibitors of human testicular 17 alpha-hydroxylase/C17,20-lyase.
    Li JS, Li Y, Son C, Brodie AM.
    J Med Chem; 1996 Oct 11; 39(21):4335-9. PubMed ID: 8863811
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  • 8. Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17).
    Hartmann RW, Hector M, Wachall BG, Palusczak A, Palzer M, Huch V, Veith M.
    J Med Chem; 2000 Nov 16; 43(23):4437-45. PubMed ID: 11087568
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  • 10. Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer.
    Potter GA, Barrie SE, Jarman M, Rowlands MG.
    J Med Chem; 1995 Jun 23; 38(13):2463-71. PubMed ID: 7608911
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  • 12. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).
    Owen CP, Shahid I, Olusanjo MS, Patel CH, Dhanani S, Ahmed S.
    J Steroid Biochem Mol Biol; 2008 Jul 23; 111(1-2):117-27. PubMed ID: 18620055
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  • 13. Tetrahydronaphthalenes: influence of heterocyclic substituents on inhibition of steroid enzymes P450 arom and P450 17.
    Wächter GA, Hartmann RW, Sergejew T, Grün GL, Ledergerber D.
    J Med Chem; 1996 Feb 16; 39(4):834-41. PubMed ID: 8632407
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  • 14. 17 beta-(cyclopropylamino)-androst-5-en-3 beta-ol, a selective mechanism-based inhibitor of cytochrome P450(17 alpha) (steroid 17 alpha-hydroxylase/C17-20 lyase).
    Angelastro MR, Laughlin ME, Schatzman GL, Bey P, Blohm TR.
    Biochem Biophys Res Commun; 1989 Aug 15; 162(3):1571-7. PubMed ID: 2788415
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  • 17. Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors.
    Numazawa M, Kamiyama T, Tachibana M, Oshibe M.
    J Med Chem; 1996 May 24; 39(11):2245-52. PubMed ID: 8667367
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  • 19. Anti-tumour effects and pharmacokinetic profile of 17-(5'-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis.
    Nnane IP, Long BJ, Ling YZ, Grigoryev DN, Brodie AM.
    Br J Cancer; 2000 Jul 24; 83(1):74-82. PubMed ID: 10883671
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  • 20. Synthesis of regioisomeric 17beta-N-phenylpyrazolyl steroid derivatives and their inhibitory effect on 17alpha-hydroxylase/C(17,20)-lyase.
    Iványi Z, Wölfling J, Görbe T, Szécsi M, Wittmann T, Schneider G.
    Steroids; 2010 Jun 24; 75(6):450-6. PubMed ID: 20206195
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