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Journal Abstract Search

157 related items for PubMed ID: 9382945

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  • 3. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
    Wright SN, Wang SY, Wang GK.
    Mol Pharmacol; 1998 Oct; 54(4):733-9. PubMed ID: 9765517
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  • 4. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel.
    Sunami A, Glaaser IW, Fozzard HA.
    Proc Natl Acad Sci U S A; 2000 Feb 29; 97(5):2326-31. PubMed ID: 10681444
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  • 6. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers.
    Nau C, Wang SY, Strichartz GR, Wang GK.
    Mol Pharmacol; 1999 Aug 29; 56(2):404-13. PubMed ID: 10419561
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  • 7. Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel.
    Qu Y, Rogers J, Tanada T, Scheuer T, Catterall WA.
    Proc Natl Acad Sci U S A; 1995 Dec 05; 92(25):11839-43. PubMed ID: 8524860
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  • 8. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
    Wang SY, Nau C, Wang GK.
    Biophys J; 2000 Sep 05; 79(3):1379-87. PubMed ID: 10969000
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  • 9. Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics.
    Sunami A, Glaaser IW, Fozzard HA.
    Mol Pharmacol; 2001 Apr 05; 59(4):684-91. PubMed ID: 11259611
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  • 10. Local anesthetics QX 572 and benzocaine act at separate sites on the batrachotoxin-activated sodium channel.
    Huang LM, Ehrenstein G.
    J Gen Physiol; 1981 Feb 05; 77(2):137-53. PubMed ID: 6267160
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  • 11. Quaternary ammonium block of mutant Na+ channels lacking inactivation: features of a transition-intermediate mechanism.
    Kimbrough JT, Gingrich KJ.
    J Physiol; 2000 Nov 15; 529 Pt 1(Pt 1):93-106. PubMed ID: 11080254
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  • 12. Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
    Wang SY, Mitchell J, Moczydlowski E, Wang GK.
    J Gen Physiol; 2004 Dec 15; 124(6):691-701. PubMed ID: 15545401
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  • 13. Batrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6.
    Wang SY, Wang GK.
    Biophys J; 1999 Jun 15; 76(6):3141-9. PubMed ID: 10354438
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  • 14. Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.
    Yarov-Yarovoy V, Brown J, Sharp EM, Clare JJ, Scheuer T, Catterall WA.
    J Biol Chem; 2001 Jan 05; 276(1):20-7. PubMed ID: 11024055
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  • 15. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels.
    Ahern CA, Eastwood AL, Dougherty DA, Horn R.
    Circ Res; 2008 Jan 04; 102(1):86-94. PubMed ID: 17967784
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  • 18. Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
    Wang SY, Wang GK.
    Proc Natl Acad Sci U S A; 1998 Mar 03; 95(5):2653-8. PubMed ID: 9482942
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  • 19. Multiple open channel states revealed by lidocaine and QX-314 on rat brain voltage-dependent sodium channels.
    Salazar BC, Castillo C, Díaz ME, Recio-Pinto E.
    J Gen Physiol; 1996 Jun 03; 107(6):743-54. PubMed ID: 8783074
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  • 20. Modeling of benzocaine analog interactions with the D4S6 segment of NaV4.1 voltage-gated sodium channels.
    Godwin SA, Cox JR, Wright SN.
    Biophys Chem; 2005 Jan 01; 113(1):1-7. PubMed ID: 15617805
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