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Journal Abstract Search

285 related items for PubMed ID: 9398307

  • 1. Molecular mechanism of regulation of the pyruvate dehydrogenase complex from E. coli.
    Hennig J, Kern G, Neef H, Spinka M, Bisswanger H, Hübner G.
    Biochemistry; 1997 Dec 16; 36(50):15772-9. PubMed ID: 9398307
    [Abstract] [Full Text] [Related]

  • 2. Interaction of thiamin diphosphate with phosphorylated and dephosphorylated mammalian pyruvate dehydrogenase complex.
    Liu X, Bisswanger H.
    Biol Chem; 2005 Jan 16; 386(1):11-8. PubMed ID: 15843142
    [Abstract] [Full Text] [Related]

  • 3. Systematic study of the six cysteines of the E1 subunit of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: none is essential for activity.
    Nemeria N, Volkov A, Brown A, Yi J, Zipper L, Guest JR, Jordan F.
    Biochemistry; 1998 Jan 20; 37(3):911-22. PubMed ID: 9454581
    [Abstract] [Full Text] [Related]

  • 4. Characterization of point mutations in patients with pyruvate dehydrogenase deficiency: role of methionine-181, proline-188, and arginine-349 in the alpha subunit.
    Tripatara A, Korotchkina LG, Patel MS.
    Arch Biochem Biophys; 1999 Jul 01; 367(1):39-50. PubMed ID: 10375397
    [Abstract] [Full Text] [Related]

  • 5. 2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.
    Brown A, Nemeria N, Yi J, Zhang D, Jordan WB, Machado RS, Guest JR, Jordan F.
    Biochemistry; 1997 Jul 01; 36(26):8071-81. PubMed ID: 9201955
    [Abstract] [Full Text] [Related]

  • 6. Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.
    Arjunan P, Chandrasekhar K, Sax M, Brunskill A, Nemeria N, Jordan F, Furey W.
    Biochemistry; 2004 Mar 09; 43(9):2405-11. PubMed ID: 14992577
    [Abstract] [Full Text] [Related]

  • 7. Direct kinetic evidence for half-of-the-sites reactivity in the E1 component of the human pyruvate dehydrogenase multienzyme complex through alternating sites cofactor activation.
    Seifert F, Golbik R, Brauer J, Lilie H, Schröder-Tittmann K, Hinze E, Korotchkina LG, Patel MS, Tittmann K.
    Biochemistry; 2006 Oct 24; 45(42):12775-85. PubMed ID: 17042496
    [Abstract] [Full Text] [Related]

  • 8. Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
    Jordan F, Nemeria NS, Zhang S, Yan Y, Arjunan P, Furey W.
    J Am Chem Soc; 2003 Oct 22; 125(42):12732-8. PubMed ID: 14558820
    [Abstract] [Full Text] [Related]

  • 9. Half-of-the-site reactivity of the decarboxylating component of the pyruvate dehydrogenase complex from pigeon breast muscle with respect to 2-hydroxyethyl thiamine pyrophosphate.
    Khailova LS, Korochkina LG.
    Biochem Int; 1985 Oct 22; 11(4):509-16. PubMed ID: 4084314
    [Abstract] [Full Text] [Related]

  • 10. 2-Acetylthiamin pyrophosphate: an enzyme-bound intermediate in thiamin pyrophosphate-dependent reactions.
    Frey PA.
    Biofactors; 1989 Mar 22; 2(1):1-9. PubMed ID: 2679649
    [Abstract] [Full Text] [Related]

  • 11. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
    Nemeria N, Baykal A, Joseph E, Zhang S, Yan Y, Furey W, Jordan F.
    Biochemistry; 2004 Jun 01; 43(21):6565-75. PubMed ID: 15157089
    [Abstract] [Full Text] [Related]

  • 12. [The effect of phosphorylation on catalytic function of muscle pyruvate dehydrogenase complex].
    Korochkina LG, Khaĭlova LS, Severin SE.
    Biokhimiia; 1993 Oct 01; 58(10):1503-12. PubMed ID: 8268295
    [Abstract] [Full Text] [Related]

  • 13.
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  • 14. Localization of tryptophan residues in thiamine pyrophosphate-binding sites of pyruvate dehydrogenase from pigeon breast muscle.
    Korochkina LG, Khailova LS, Severin SE.
    Biochem Int; 1984 Oct 01; 9(4):491-9. PubMed ID: 6517955
    [Abstract] [Full Text] [Related]

  • 15. Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states.
    Nemeria N, Korotchkina L, McLeish MJ, Kenyon GL, Patel MS, Jordan F.
    Biochemistry; 2007 Sep 18; 46(37):10739-44. PubMed ID: 17715948
    [Abstract] [Full Text] [Related]

  • 16. Effect of substitutions in the thiamin diphosphate-magnesium fold on the activation of the pyruvate dehydrogenase complex from Escherichia coli by cofactors and substrate.
    Yi J, Nemeria N, McNally A, Jordan F, Machado RS, Guest JR.
    J Biol Chem; 1996 Dec 27; 271(52):33192-200. PubMed ID: 8969175
    [Abstract] [Full Text] [Related]

  • 17. Regulatory properties of the pyruvate dehydrogenase complex from Escherichia coli. Studies on the thiamin diphosphate-dependent lag phase.
    Horn F, Bisswanger H.
    J Biol Chem; 1983 Jun 10; 258(11):6912-9. PubMed ID: 6304062
    [Abstract] [Full Text] [Related]

  • 18. Elementary steps in the reaction of the pyruvate dehydrogenase complex from pig heart. Kinetics of thiamine diphosphate binding to the complex.
    Sümegi B, Alkonyi I.
    Eur J Biochem; 1983 Nov 02; 136(2):347-53. PubMed ID: 6628385
    [Abstract] [Full Text] [Related]

  • 19. Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
    Liu S, Gong X, Yan X, Peng T, Baker JC, Li L, Robben PM, Ravindran S, Andersson LA, Cole AB, Roche TE.
    Arch Biochem Biophys; 2001 Feb 15; 386(2):123-35. PubMed ID: 11368334
    [Abstract] [Full Text] [Related]

  • 20. Activation of thiamin diphosphate in enzymes.
    Hübner G, Tittmann K, Killenberg-Jabs M, Schäffner J, Spinka M, Neef H, Kern D, Kern G, Schneider G, Wikner C, Ghisla S.
    Biochim Biophys Acta; 1998 Jun 29; 1385(2):221-8. PubMed ID: 9655909
    [Abstract] [Full Text] [Related]

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