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Journal Abstract Search
404 related items for PubMed ID: 9406243
1. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy. Begleiter A, Leith MK, Curphey TJ, Doherty GP. Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243 [Abstract] [Full Text] [Related]
2. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase. Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A. Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423 [Abstract] [Full Text] [Related]
3. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase. Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A. Br J Cancer; 1999 Jun; 80(8):1223-30. PubMed ID: 10376975 [Abstract] [Full Text] [Related]
4. Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents. Doherty GP, Leith MK, Wang X, Curphey TJ, Begleiter A. Br J Cancer; 1998 Apr; 77(8):1241-52. PubMed ID: 9579829 [Abstract] [Full Text] [Related]
5. Cellular kinetics of induction by oltipraz and its keto derivative of detoxication enzymes in human colon adenocarcinoma cells. O'Dwyer PJ, Clayton M, Halbherr T, Myers CB, Yao Ks. Clin Cancer Res; 1997 May; 3(5):783-91. PubMed ID: 9815750 [Abstract] [Full Text] [Related]
6. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines. Beall HD, Murphy AM, Siegel D, Hargreaves RH, Butler J, Ross D. Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631 [Abstract] [Full Text] [Related]
7. Induction of DT-diaphorase by 1,2-dithiole-3-thione and increase of antitumour activity of bioreductive agents. Begleiter A, Leith MK, Curphey TJ. Br J Cancer Suppl; 1996 Jul; 27():S9-14. PubMed ID: 8763837 [Abstract] [Full Text] [Related]
8. Lack of NQO1 induction in human tumor cells is not due to changes in the promoter region of the gene. Begleiter A, Lange L. Int J Oncol; 2002 Apr; 20(4):835-8. PubMed ID: 11894133 [Abstract] [Full Text] [Related]
9. Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase. Workman P. Oncol Res; 1994 Apr; 6(10-11):461-75. PubMed ID: 7620214 [Abstract] [Full Text] [Related]
10. Effect of NQO1 induction on the antitumor activity of RH1 in human tumors in vitro and in vivo. Digby T, Leith MK, Thliveris JA, Begleiter A. Cancer Chemother Pharmacol; 2005 Sep; 56(3):307-16. PubMed ID: 15877230 [Abstract] [Full Text] [Related]
11. Advances in research on DT-diaphorase--catalytic properties, regulation of activity and significance in the detoxication of foreign compounds. Horie S. Kitasato Arch Exp Med; 1990 Apr; 63(1):11-30. PubMed ID: 2125671 [Abstract] [Full Text] [Related]
12. Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: implications for enzyme-directed bioreductive drug development. Phillips RM, Burger AM, Loadman PM, Jarrett CM, Swaine DJ, Fiebig HH. Cancer Res; 2000 Nov 15; 60(22):6384-90. PubMed ID: 11103802 [Abstract] [Full Text] [Related]
13. Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł. Malkinson AM, Siegel D, Forrest GL, Gazdar AF, Oie HK, Chan DC, Bunn PA, Mabry M, Dykes DJ, Harrison SD. Cancer Res; 1992 Sep 01; 52(17):4752-7. PubMed ID: 1324793 [Abstract] [Full Text] [Related]
14. Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz. Roebuck BD, Curphey TJ, Li Y, Baumgartner KJ, Bodreddigari S, Yan J, Gange SJ, Kensler TW, Sutter TR. Carcinogenesis; 2003 Dec 01; 24(12):1919-28. PubMed ID: 14555609 [Abstract] [Full Text] [Related]
15. Factors influencing the induction of DT-diaphorase activity by 1,2-dithiole-3-thione in human tumor cell lines. Begleiterabc A, Leith MK, Doherty GP, Digbya TJ, Pan S. Biochem Pharmacol; 2001 Apr 15; 61(8):955-64. PubMed ID: 11286987 [Abstract] [Full Text] [Related]
16. Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9. Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R, Lewis AD. J Natl Cancer Inst; 1996 Mar 06; 88(5):259-69. PubMed ID: 8614004 [Abstract] [Full Text] [Related]
17. Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs. Powis G, Gasdaska PY, Gallegos A, Sherrill K, Goodman D. Anticancer Res; 1995 Mar 06; 15(4):1141-5. PubMed ID: 7653992 [Abstract] [Full Text] [Related]
18. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C. Saeki S, Nishiyama M, Toge T. Hiroshima J Med Sci; 1995 Sep 06; 44(3):55-63. PubMed ID: 8567314 [Abstract] [Full Text] [Related]
19. Induction of DT-diaphorase by doxorubicin and combination therapy with mitomycin C in vitro. Begleiter A, Leith MK. Biochem Pharmacol; 1995 Oct 12; 50(8):1281-6. PubMed ID: 7488245 [Abstract] [Full Text] [Related]
20. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent. Winski SL, Hargreaves RH, Butler J, Ross D. Clin Cancer Res; 1998 Dec 12; 4(12):3083-8. PubMed ID: 9865924 [Abstract] [Full Text] [Related] Page: [Next] [New Search]