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326 related items for PubMed ID: 9409294

  • 1. Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase in rat hepatocytes.
    Post SM, de Wit EC, Princen HM.
    Arterioscler Thromb Vasc Biol; 1997 Nov; 17(11):3064-70. PubMed ID: 9409294
    [Abstract] [Full Text] [Related]

  • 2. Effect of coffee lipids (cafestol and kahweol) on regulation of cholesterol metabolism in HepG2 cells.
    Rustan AC, Halvorsen B, Huggett AC, Ranheim T, Drevon CA.
    Arterioscler Thromb Vasc Biol; 1997 Oct; 17(10):2140-9. PubMed ID: 9351383
    [Abstract] [Full Text] [Related]

  • 3. Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase gene transcription.
    Twisk J, Hoekman MF, Lehmann EM, Meijer P, Mager WH, Princen HM.
    Hepatology; 1995 Feb; 21(2):501-10. PubMed ID: 7843724
    [Abstract] [Full Text] [Related]

  • 4. Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes.
    Twisk J, de Wit EC, Princen HM.
    Biochem J; 1995 Jan 15; 305 ( Pt 2)(Pt 2):505-11. PubMed ID: 7832767
    [Abstract] [Full Text] [Related]

  • 5. Regulation of bile acid synthesis by deoxycholic acid in the rat: different effects on cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase.
    Shefer S, Kren BT, Salen G, Steer CJ, Nguyen LB, Chen T, Tint GS, Batta AK.
    Hepatology; 1995 Oct 15; 22(4 Pt 1):1215-21. PubMed ID: 7557873
    [Abstract] [Full Text] [Related]

  • 6. Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-alpha-mediated downregulation of cholesterol 7alpha-hydroxylase and sterol 27-hydroxylase expression.
    Post SM, Duez H, Gervois PP, Staels B, Kuipers F, Princen HM.
    Arterioscler Thromb Vasc Biol; 2001 Nov 15; 21(11):1840-5. PubMed ID: 11701475
    [Abstract] [Full Text] [Related]

  • 7. Structural aspects of bile acids involved in the regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase.
    Twisk J, Hoekman MF, Muller LM, Iida T, Tamaru T, Ijzerman A, Mager WH, Princen HM.
    Eur J Biochem; 1995 Mar 15; 228(3):596-604. PubMed ID: 7737153
    [Abstract] [Full Text] [Related]

  • 8. Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7alpha-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes.
    Post SM, Twisk J, van der Fits L, de Wit EC, Hoekman MF, Mager WH, Princen HM.
    Biochem J; 1999 Jul 15; 341 ( Pt 2)(Pt 2):339-46. PubMed ID: 10393091
    [Abstract] [Full Text] [Related]

  • 9. Cafestol increases serum cholesterol levels in apolipoprotein E*3-Leiden transgenic mice by suppression of bile acid synthesis.
    Post SM, de Roos B, Vermeulen M, Afman L, Jong MC, Dahlmans VE, Havekes LM, Stellaard F, Katan MB, Princen HM.
    Arterioscler Thromb Vasc Biol; 2000 Jun 15; 20(6):1551-6. PubMed ID: 10845871
    [Abstract] [Full Text] [Related]

  • 10. The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.
    Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen CJ, Müller M, Frants RR, Kasanmoentalib S, Post SM, Princen HM, Porter JG, Katan MB, Hofker MH, Moore DD.
    Mol Endocrinol; 2007 Jul 15; 21(7):1603-16. PubMed ID: 17456796
    [Abstract] [Full Text] [Related]

  • 11. Regulation of hepatic sterol metabolism in the rat. Parallel regulation of activity and mRNA for 7 alpha-hydroxylase but not 3-hydroxy-3-methylglutaryl-coenzyme A reductase or low density lipoprotein receptor.
    Spady DK, Cuthbert JA.
    J Biol Chem; 1992 Mar 15; 267(8):5584-91. PubMed ID: 1544932
    [Abstract] [Full Text] [Related]

  • 12. Transcriptional regulation of hepatic sterol 27-hydroxylase by bile acids.
    Vlahcevic ZR, Jairath SK, Heuman DM, Stravitz RT, Hylemon PB, Avadhani NG, Pandak WM.
    Am J Physiol; 1996 Apr 15; 270(4 Pt 1):G646-52. PubMed ID: 8928794
    [Abstract] [Full Text] [Related]

  • 13. Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts.
    Halvorsen B, Ranheim T, Nenseter MS, Huggett AC, Drevon CA.
    J Lipid Res; 1998 Apr 15; 39(4):901-12. PubMed ID: 9555953
    [Abstract] [Full Text] [Related]

  • 14. Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes.
    Stravitz RT, Vlahcevic ZR, Russell TL, Heizer ML, Avadhani NG, Hylemon PB.
    J Steroid Biochem Mol Biol; 1996 Mar 15; 57(5-6):337-47. PubMed ID: 8639470
    [Abstract] [Full Text] [Related]

  • 15. Regulation of classic and alternative bile acid synthesis in hypercholesterolemic rabbits: effects of cholesterol feeding and bile acid depletion.
    Xu G, Salen G, Shefer S, Tint GS, Nguyen LB, Parker TT, Chen TS, Roberts J, Kong X, Greenblatt D.
    J Lipid Res; 1998 Aug 15; 39(8):1608-15. PubMed ID: 9717721
    [Abstract] [Full Text] [Related]

  • 16. Effect of squalene synthase inhibition on the expression of hepatic cholesterol biosynthetic enzymes, LDL receptor, and cholesterol 7 alpha hydroxylase.
    Ness GC, Zhao Z, Keller RK.
    Arch Biochem Biophys; 1994 Jun 15; 311(2):277-85. PubMed ID: 7911291
    [Abstract] [Full Text] [Related]

  • 17. Increased bile acid pool inhibits cholesterol 7 alpha-hydroxylase in cholesterol-fed rabbits.
    Xu G, Salen G, Shefer S, Tint GS, Kren BT, Nguyen LB, Steer CJ, Chen TS, Salen L, Greenblatt D.
    Gastroenterology; 1997 Dec 15; 113(6):1958-65. PubMed ID: 9394736
    [Abstract] [Full Text] [Related]

  • 18. Regulation of cholesterol 7 alpha-hydroxylase gene expression in Hep-G2 cells. Effect of serum, bile salts, and coordinate and noncoordinate regulation with other sterol-responsive genes.
    Taniguchi T, Chen J, Cooper AD.
    J Biol Chem; 1994 Apr 01; 269(13):10071-8. PubMed ID: 8144506
    [Abstract] [Full Text] [Related]

  • 19. Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
    Post SM, Zoeteweij JP, Bos MH, de Wit EC, Havinga R, Kuipers F, Princen HM.
    Hepatology; 1999 Aug 01; 30(2):491-500. PubMed ID: 10421659
    [Abstract] [Full Text] [Related]

  • 20. Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1.
    Björkhem I, Araya Z, Rudling M, Angelin B, Einarsson C, Wikvall K.
    J Biol Chem; 2002 Jul 26; 277(30):26804-7. PubMed ID: 12011083
    [Abstract] [Full Text] [Related]

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