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Journal Abstract Search

96 related items for PubMed ID: 9414255

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  • 4. Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells.
    Volpato JP, Mayotte N, Fossati E, Guerrero V, Sauvageau G, Pelletier JN.
    J Mol Recognit; 2011; 24(2):188-98. PubMed ID: 21360609
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  • 9. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
    Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, Bertino JR.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3400-5. PubMed ID: 11891321
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  • 11. Dihydrofolate reductase mutant with exceptional resistance to methotrexate but not to trimetrexate.
    Pineda P, Kanter A, McIvor RS, Benkovic SJ, Rosowsky A, Wagner CR.
    J Med Chem; 2003 Jul 03; 46(14):2816-8. PubMed ID: 12825924
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  • 12. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
    Liani E, Rothem L, Bunni MA, Smith CA, Jansen G, Assaraf YG.
    Int J Cancer; 2003 Feb 20; 103(5):587-99. PubMed ID: 12494465
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  • 13. A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs.
    Galipeau J, Benaim E, Spencer HT, Blakley RL, Sorrentino BP.
    Hum Gene Ther; 1997 Oct 10; 8(15):1773-83. PubMed ID: 9358027
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  • 14. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL, McQueen CA, DeAngelis LM, Bertino JR.
    Cancer Res; 1976 Jul 10; 36(7 PT 1):2442-9. PubMed ID: 1277151
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  • 15. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H, Niethammer D, Jackson RC.
    Cancer Res; 1983 Nov 10; 43(11):5286-92. PubMed ID: 6225514
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  • 16. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 10; 46(2):588-93. PubMed ID: 2416428
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  • 17. Mechanisms of sensitivity and natural resistance to antifolates in a methylcholanthrene-induced rat sarcoma.
    Li WW, Lin JT, Schweitzer BI, Bertino JR.
    Mol Pharmacol; 1991 Nov 10; 40(5):854-8. PubMed ID: 1719370
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  • 18. Characterization of a lipophilic antifolate resistance provoked by treatment of mammalian cells with the antiparasitic agent pyrimethamine.
    Assaraf YG, Slotky JI.
    J Biol Chem; 1993 Feb 25; 268(6):4556-66. PubMed ID: 8440739
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  • 19. New antifolates in clinical development.
    Takimoto CH, Allegra CJ.
    Oncology (Williston Park); 1995 Jul 25; 9(7):649-56, 659 DISC 660, 662, 665. PubMed ID: 8924375
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  • 20. In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics.
    Rana RM, Rampogu S, Abid NB, Zeb A, Parate S, Lee G, Yoon S, Kim Y, Kim D, Lee KW.
    Molecules; 2020 Jul 31; 25(15):. PubMed ID: 32752079
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