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Journal Abstract Search

191 related items for PubMed ID: 9414600

  • 1. [Lethal drug interactions of the new antiviral, sorivudine, with anticancer prodrugs of 5-fluorouracil].
    Watabe T, Okuda H, Ogura K.
    Yakugaku Zasshi; 1997 Nov; 117(10-11):910-21. PubMed ID: 9414600
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  • 2. A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    Okuda H, Ogura K, Kato A, Takubo H, Watabe T.
    J Pharmacol Exp Ther; 1998 Nov; 287(2):791-9. PubMed ID: 9808711
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  • 3. Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    Okuda H, Nishiyama T, Ogura K, Nagayama S, Ikeda K, Yamaguchi S, Nakamura Y, Kawaguchi K, Watabe T, Ogura Y.
    Drug Metab Dispos; 1997 Feb; 25(2):270-3. PubMed ID: 9029059
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  • 4. Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    Okuda H, Nishiyama T, Ogura K, Nagayama S, Ikeda K, Yamaguchi S, Nakamura Y, Kawaguchi Y, Watabe T.
    Drug Metab Dispos; 1997 May; 25(5):270-3. PubMed ID: 9152608
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  • 5. [Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
    Watabe T, Ogura K, Nishiyama T.
    Yakugaku Zasshi; 2002 Aug; 122(8):527-35. PubMed ID: 12187768
    [Abstract] [Full Text] [Related]

  • 6. Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine.
    Ogura K, Nishiyama T, Takubo H, Kato A, Okuda H, Arakawa K, Fukushima M, Nagayama S, Kawaguchi Y, Watabe T.
    Cancer Lett; 1998 Jan 09; 122(1-2):107-13. PubMed ID: 9464498
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  • 7. The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
    Yan J, Tyring SK, McCrary MM, Lee PC, Haworth S, Raymond R, Olsen SJ, Diasio RB.
    Clin Pharmacol Ther; 1997 May 09; 61(5):563-73. PubMed ID: 9164418
    [Abstract] [Full Text] [Related]

  • 8. Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.
    Nakayama H, Kinouchi T, Kataoka K, Akimoto S, Matsuda Y, Ohnishi Y.
    Pharmacogenetics; 1997 Feb 09; 7(1):35-43. PubMed ID: 9110360
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  • 9. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase.
    Diasio RB.
    Br J Clin Pharmacol; 1998 Jul 09; 46(1):1-4. PubMed ID: 9690942
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  • 14. Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators.
    Shirasaka T, Shimamato Y, Ohshimo H, Yamaguchi M, Kato T, Yonekura K, Fukushima M.
    Anticancer Drugs; 1996 Jul 09; 7(5):548-57. PubMed ID: 8862723
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  • 19. Drug delivery of oral anti-cancer fluoropyrimidine agents.
    Miura K, Shima H, Takebe N, Rhie J, Satoh K, Kakugawa Y, Satoh M, Kinouchi M, Yamamoto K, Hasegawa Y, Kawai M, Kanazawa K, Fujiya T, Unno M, Katakura R.
    Expert Opin Drug Deliv; 2017 Dec 09; 14(12):1355-1366. PubMed ID: 28379040
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