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1161 related items for PubMed ID: 9426068

  • 1. Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha.
    Santoni-Rugiu E, Jensen MR, Thorgeirsson SS.
    Cancer Res; 1998 Jan 01; 58(1):123-34. PubMed ID: 9426068
    [Abstract] [Full Text] [Related]

  • 2. Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis.
    Conner EA, Lemmer ER, Omori M, Wirth PJ, Factor VM, Thorgeirsson SS.
    Oncogene; 2000 Oct 19; 19(44):5054-62. PubMed ID: 11042693
    [Abstract] [Full Text] [Related]

  • 3. Cell cycle basis for the onset and progression of c-Myc-induced, TGFalpha-enhanced mouse mammary gland carcinogenesis.
    Liao DJ, Natarajan G, Deming SL, Jamerson MH, Johnson M, Chepko G, Dickson RB.
    Oncogene; 2000 Mar 02; 19(10):1307-17. PubMed ID: 10713672
    [Abstract] [Full Text] [Related]

  • 4. Evolution of neoplastic development in the liver of transgenic mice co-expressing c-myc and transforming growth factor-alpha.
    Santoni-Rugiu E, Nagy P, Jensen MR, Factor VM, Thorgeirsson SS.
    Am J Pathol; 1996 Aug 02; 149(2):407-28. PubMed ID: 8701981
    [Abstract] [Full Text] [Related]

  • 5. Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis.
    Pascale RM, Simile MM, De Miglio MR, Muroni MR, Calvisi DF, Asara G, Casabona D, Frau M, Seddaiu MA, Feo F.
    Hepatology; 2002 Jun 02; 35(6):1341-50. PubMed ID: 12029619
    [Abstract] [Full Text] [Related]

  • 6. p120-v-Abl expression overcomes TGF-beta1 negative regulation of c-myc transcription but not cell growth.
    Birchenall-Roberts MC, Kim SJ, Bertolette DC, Turley JM, Fu T, Bang OS, Kasper JJ, Yoo YD, Ruscetti FW.
    Oncogene; 1996 Oct 03; 13(7):1499-509. PubMed ID: 8875988
    [Abstract] [Full Text] [Related]

  • 7. Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.
    Alevizopoulos K, Vlach J, Hennecke S, Amati B.
    EMBO J; 1997 Sep 01; 16(17):5322-33. PubMed ID: 9311992
    [Abstract] [Full Text] [Related]

  • 8. The retinoblastoma gene product inhibits TGF-beta1 induced apoptosis in primary rat hepatocytes and human HuH-7 hepatoma cells.
    Fan G, Ma X, Kren BT, Steer CJ.
    Oncogene; 1996 May 02; 12(9):1909-19. PubMed ID: 8649852
    [Abstract] [Full Text] [Related]

  • 9. Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer.
    Calvisi DF, Thorgeirsson SS.
    Toxicol Pathol; 2005 May 02; 33(1):181-4. PubMed ID: 15805070
    [Abstract] [Full Text] [Related]

  • 10. Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2.
    Chen Q, Hung FC, Fromm L, Overbeek PA.
    Invest Ophthalmol Vis Sci; 2000 Dec 02; 41(13):4223-31. PubMed ID: 11095619
    [Abstract] [Full Text] [Related]

  • 11. The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering.
    Alesse E, Zazzeroni F, Angelucci A, Giannini G, Di Marcotullio L, Gulino A.
    Cell Death Differ; 1998 May 02; 5(5):381-9. PubMed ID: 10200487
    [Abstract] [Full Text] [Related]

  • 12. c-myc-enhanced S phase entry in keratinocytes is associated with positive and negative effects on cyclin-dependent kinases.
    Alexandrow MG, Moses HL.
    J Cell Biochem; 1998 Sep 15; 70(4):528-42. PubMed ID: 9712150
    [Abstract] [Full Text] [Related]

  • 13. Activation of beta-catenin provides proliferative and invasive advantages in c-myc/TGF-alpha hepatocarcinogenesis promoted by phenobarbital.
    Calvisi DF, Ladu S, Factor VM, Thorgeirsson SS.
    Carcinogenesis; 2004 Jun 15; 25(6):901-8. PubMed ID: 14742323
    [Abstract] [Full Text] [Related]

  • 14. Transforming growth factor beta inhibits the phosphorylation of pRB at multiple serine/threonine sites and differentially regulates the formation of pRB family-E2F complexes in human myeloid leukemia cells.
    Hu X, Cress WD, Zhong Q, Zuckerman KS.
    Biochem Biophys Res Commun; 2000 Oct 05; 276(3):930-9. PubMed ID: 11027571
    [Abstract] [Full Text] [Related]

  • 15. Coexpression of C-myc and transforming growth factor alfa in the liver promotes early replicative senescence and diminishes regenerative capacity after partial hepatectomy in transgenic mice.
    Factor VM, Jensen MR, Thorgeirsson SS.
    Hepatology; 1997 Dec 05; 26(6):1434-43. PubMed ID: 9397983
    [Abstract] [Full Text] [Related]

  • 16. Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1.
    Roussel MF, Davis JN, Cleveland JL, Ghysdael J, Hiebert SW.
    Oncogene; 1994 Feb 05; 9(2):405-15. PubMed ID: 8290253
    [Abstract] [Full Text] [Related]

  • 17. Involvement of retinoblastoma (Rb) and E2F transcription factors during photodynamic therapy of human epidermoid carcinoma cells A431.
    Ahmad N, Gupta S, Mukhtar H.
    Oncogene; 1999 Mar 11; 18(10):1891-6. PubMed ID: 10086343
    [Abstract] [Full Text] [Related]

  • 18. Vitamin E succinate inhibits proliferation of BT-20 human breast cancer cells: increased binding of cyclin A negatively regulates E2F transactivation activity.
    Turley JM, Ruscetti FW, Kim SJ, Fu T, Gou FV, Birchenall-Roberts MC.
    Cancer Res; 1997 Jul 01; 57(13):2668-75. PubMed ID: 9205075
    [Abstract] [Full Text] [Related]

  • 19. E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions.
    Oswald F, Lovec H, Möröy T, Lipp M.
    Oncogene; 1994 Jul 01; 9(7):2029-36. PubMed ID: 8208548
    [Abstract] [Full Text] [Related]

  • 20. Caspase activation and changes in Bcl-2 family member protein expression associated with E2F-1-mediated apoptosis in human esophageal cancer cells.
    Yang HL, Dong YB, Elliott MJ, Liu TJ, McMasters KM.
    Clin Cancer Res; 2000 Apr 01; 6(4):1579-89. PubMed ID: 10778992
    [Abstract] [Full Text] [Related]

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