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115 related items for PubMed ID: 9427376

  • 1. Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.
    Mattson MP, Robinson N, Guo Q.
    Neuroreport; 1997 Dec 01; 8(17):3817-21. PubMed ID: 9427376
    [Abstract] [Full Text] [Related]

  • 2. Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.
    Guo Q, Fu W, Holtsberg FW, Steiner SM, Mattson MP.
    J Neurosci Res; 1999 Jun 01; 56(5):457-70. PubMed ID: 10369213
    [Abstract] [Full Text] [Related]

  • 3. Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
    Guo Q, Sopher BL, Furukawa K, Pham DG, Robinson N, Martin GM, Mattson MP.
    J Neurosci; 1997 Jun 01; 17(11):4212-22. PubMed ID: 9151738
    [Abstract] [Full Text] [Related]

  • 4. Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.
    Guo Q, Robinson N, Mattson MP.
    J Biol Chem; 1998 May 15; 273(20):12341-51. PubMed ID: 9575187
    [Abstract] [Full Text] [Related]

  • 5. Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function.
    Guo Q, Christakos S, Robinson N, Mattson MP.
    Proc Natl Acad Sci U S A; 1998 Mar 17; 95(6):3227-32. PubMed ID: 9501245
    [Abstract] [Full Text] [Related]

  • 6. Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.
    Keller JN, Guo Q, Holtsberg FW, Bruce-Keller AJ, Mattson MP.
    J Neurosci; 1998 Jun 15; 18(12):4439-50. PubMed ID: 9614221
    [Abstract] [Full Text] [Related]

  • 7. Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation.
    Chan SL, Tammariello SP, Estus S, Mattson MP.
    J Neurochem; 1999 Aug 15; 73(2):502-12. PubMed ID: 10428045
    [Abstract] [Full Text] [Related]

  • 8. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA.
    J Neurochem; 2006 Mar 15; 96(5):1322-35. PubMed ID: 16478525
    [Abstract] [Full Text] [Related]

  • 9. AATF protects neural cells against oxidative damage induced by amyloid beta-peptide.
    Xie J, Guo Q.
    Neurobiol Dis; 2004 Jun 15; 16(1):150-7. PubMed ID: 15207272
    [Abstract] [Full Text] [Related]

  • 10. Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis.
    Wang H, Xu H, Dyck LE, Li XM.
    J Neurosci Res; 2005 Aug 15; 81(4):572-80. PubMed ID: 15948179
    [Abstract] [Full Text] [Related]

  • 11. Protective effects of [Gly14]-Humanin on beta-amyloid-induced PC12 cell death by preventing mitochondrial dysfunction.
    Jin H, Liu T, Wang WX, Xu JH, Yang PB, Lu HX, Sun QR, Hu HT.
    Neurochem Int; 2010 Feb 15; 56(3):417-23. PubMed ID: 19941922
    [Abstract] [Full Text] [Related]

  • 12. 17β-estradiol protects cerebellar granule cells against β-amyloid-induced toxicity via the apoptotic mitochondrial pathway.
    Napolitano M, Costa L, Piacentini R, Grassi C, Lanzone A, Gulino A.
    Neurosci Lett; 2014 Feb 21; 561():134-9. PubMed ID: 24287378
    [Abstract] [Full Text] [Related]

  • 13. Protective effects of galantamine against Abeta-induced PC12 cell apoptosis by preventing mitochondrial dysfunction and endoplasmic reticulum stress.
    Liu X, Xu K, Yan M, Wang Y, Zheng X.
    Neurochem Int; 2010 Nov 21; 57(5):588-99. PubMed ID: 20655346
    [Abstract] [Full Text] [Related]

  • 14. Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function.
    Nilsen J, Chen S, Irwin RW, Iwamoto S, Brinton RD.
    BMC Neurosci; 2006 Nov 03; 7():74. PubMed ID: 17083736
    [Abstract] [Full Text] [Related]

  • 15. Valproic acid attenuates Aβ25-35-induced neurotoxicity in PC12 cells through suppression of mitochondria-mediated apoptotic pathway.
    Zhao L, Zhu L, Guo X.
    Biomed Pharmacother; 2018 Oct 03; 106():77-82. PubMed ID: 29957469
    [Abstract] [Full Text] [Related]

  • 16. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.
    Mattson MP, Guo Q, Furukawa K, Pedersen WA.
    J Neurochem; 1998 Jan 03; 70(1):1-14. PubMed ID: 9422341
    [Abstract] [Full Text] [Related]

  • 17. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
    Guo Q, Sebastian L, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP.
    J Neurochem; 1999 Mar 03; 72(3):1019-29. PubMed ID: 10037473
    [Abstract] [Full Text] [Related]

  • 18. Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice.
    Xie J, Chang X, Zhang X, Guo Q.
    Brain Res; 2001 Oct 05; 915(1):1-10. PubMed ID: 11578614
    [Abstract] [Full Text] [Related]

  • 19. Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.
    Guo Q, Fu W, Xie J, Luo H, Sells SF, Geddes JW, Bondada V, Rangnekar VM, Mattson MP.
    Nat Med; 1998 Aug 05; 4(8):957-62. PubMed ID: 9701251
    [Abstract] [Full Text] [Related]

  • 20. Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells.
    Martín D, Salinas M, López-Valdaliso R, Serrano E, Recuero M, Cuadrado A.
    J Neurochem; 2001 Sep 05; 78(5):1000-8. PubMed ID: 11553674
    [Abstract] [Full Text] [Related]

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