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Journal Abstract Search

275 related items for PubMed ID: 9428731

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  • 3. Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants.
    Quintas A, Vaz DC, Cardoso I, Saraiva MJ, Brito RM.
    J Biol Chem; 2001 Jul 20; 276(29):27207-13. PubMed ID: 11306576
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  • 4. Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin.
    Shnyrov VL, Villar E, Zhadan GG, Sanchez-Ruiz JM, Quintas A, Saraiva MJ, Brito RM.
    Biophys Chem; 2000 Dec 15; 88(1-3):61-7. PubMed ID: 11152276
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  • 5. Trapping the monomer of a non-amyloidogenic variant of transthyretin: exploring its possible use as a therapeutic strategy against transthyretin amyloidogenic diseases.
    Palhano FL, Leme LP, Busnardo RG, Foguel D.
    J Biol Chem; 2009 Jan 16; 284(3):1443-53. PubMed ID: 18984591
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  • 6. The tetrameric protein transthyretin dissociates to a non-native monomer in solution. A novel model for amyloidogenesis.
    Quintas A, Saraiva MJ, Brito RM.
    J Biol Chem; 1999 Nov 12; 274(46):32943-9. PubMed ID: 10551861
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  • 7. The most pathogenic transthyretin variant, L55P, forms amyloid fibrils under acidic conditions and protofilaments under physiological conditions.
    Lashuel HA, Wurth C, Woo L, Kelly JW.
    Biochemistry; 1999 Oct 12; 38(41):13560-73. PubMed ID: 10521263
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  • 8. Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease.
    Ferrão-Gonzales AD, Palmieri L, Valory M, Silva JL, Lashuel H, Kelly JW, Foguel D.
    J Mol Biol; 2003 May 09; 328(4):963-74. PubMed ID: 12729768
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  • 9. Potentially amyloidogenic conformational intermediates populate the unfolding landscape of transthyretin: insights from molecular dynamics simulations.
    Rodrigues JR, Simões CJ, Silva CG, Brito RM.
    Protein Sci; 2010 Feb 09; 19(2):202-19. PubMed ID: 19937650
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  • 10. A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.
    Jesus CS, Almeida ZL, Vaz DC, Faria TQ, Brito RM.
    Int J Mol Sci; 2016 Aug 31; 17(9):. PubMed ID: 27589730
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  • 11. Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease.
    McCutchen SL, Lai Z, Miroy GJ, Kelly JW, Colón W.
    Biochemistry; 1995 Oct 17; 34(41):13527-36. PubMed ID: 7577941
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  • 12. Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy.
    Taguchi K, Jono H, Kugimiya-Taguchi T, Nagao S, Su Y, Yamasaki K, Mizuguchi M, Maruyama T, Ando Y, Otagiri M.
    Life Sci; 2013 Dec 18; 93(25-26):1017-22. PubMed ID: 24211615
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  • 13. Clusterin regulates transthyretin amyloidosis.
    Lee KW, Lee DH, Son H, Kim YS, Park JY, Roh GS, Kim HJ, Kang SS, Cho GJ, Choi WS.
    Biochem Biophys Res Commun; 2009 Oct 16; 388(2):256-60. PubMed ID: 19664600
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  • 14. Why is Leu55-->Pro55 transthyretin variant the most amyloidogenic: insights from molecular dynamics simulations of transthyretin monomers.
    Yang M, Lei M, Huo S.
    Protein Sci; 2003 Jun 16; 12(6):1222-31. PubMed ID: 12761393
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  • 15. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid.
    Lai Z, Colón W, Kelly JW.
    Biochemistry; 1996 May 21; 35(20):6470-82. PubMed ID: 8639594
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  • 16. Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants.
    Schwarzman AL, Tsiper M, Wente H, Wang A, Vitek MP, Vasiliev V, Goldgaber D.
    Amyloid; 2004 Mar 21; 11(1):1-9. PubMed ID: 15185492
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  • 17. Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in cerebrospinal fluid.
    Azevedo EP, Pereira HM, Garratt RC, Kelly JW, Foguel D, Palhano FL.
    Biochemistry; 2011 Dec 27; 50(51):11070-83. PubMed ID: 22091638
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  • 18. Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity.
    Hou X, Richardson SJ, Aguilar MI, Small DH.
    Biochemistry; 2005 Aug 30; 44(34):11618-27. PubMed ID: 16114899
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  • 19. Quantification of the thermodynamically linked quaternary and tertiary structural stabilities of transthyretin and its disease-associated variants: the relationship between stability and amyloidosis.
    Hurshman Babbes AR, Powers ET, Kelly JW.
    Biochemistry; 2008 Jul 01; 47(26):6969-84. PubMed ID: 18537267
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  • 20. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
    Foguel D, Suarez MC, Ferrão-Gonzales AD, Porto TC, Palmieri L, Einsiedler CM, Andrade LR, Lashuel HA, Lansbury PT, Kelly JW, Silva JL.
    Proc Natl Acad Sci U S A; 2003 Aug 19; 100(17):9831-6. PubMed ID: 12900507
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