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263 related items for PubMed ID: 9435181

  • 1. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury.
    Baker K, Marcus CB, Huffman K, Kruk H, Malfroy B, Doctrow SR.
    J Pharmacol Exp Ther; 1998 Jan; 284(1):215-21. PubMed ID: 9435181
    [Abstract] [Full Text] [Related]

  • 2. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies.
    Doctrow SR, Huffman K, Marcus CB, Tocco G, Malfroy E, Adinolfi CA, Kruk H, Baker K, Lazarowych N, Mascarenhas J, Malfroy B.
    J Med Chem; 2002 Sep 26; 45(20):4549-58. PubMed ID: 12238934
    [Abstract] [Full Text] [Related]

  • 3. EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.
    Gonzalez PK, Zhuang J, Doctrow SR, Malfroy B, Benson PF, Menconi MJ, Fink MP.
    J Pharmacol Exp Ther; 1995 Nov 26; 275(2):798-806. PubMed ID: 7473169
    [Abstract] [Full Text] [Related]

  • 4. Using superoxide dismutase/catalase mimetics to manipulate the redox environment of neural precursor cells.
    Limoli CL, Giedzinski E, Baure J, Doctrow SR, Rola R, Fike JR.
    Radiat Prot Dosimetry; 2006 Nov 26; 122(1-4):228-36. PubMed ID: 17166877
    [Abstract] [Full Text] [Related]

  • 5. Salen-manganese complexes: sophisticated tools for the analysis of intercellular ROS signaling pathways.
    Ophoven SJ, Bauer G.
    Anticancer Res; 2010 Oct 26; 30(10):3967-79. PubMed ID: 21036710
    [Abstract] [Full Text] [Related]

  • 6. Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans.
    Keaney M, Matthijssens F, Sharpe M, Vanfleteren J, Gems D.
    Free Radic Biol Med; 2004 Jul 15; 37(2):239-50. PubMed ID: 15203195
    [Abstract] [Full Text] [Related]

  • 7. Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion.
    Lysiak JJ, Nguyen QA, Turner TT.
    J Androl; 2002 Jul 15; 23(3):400-9. PubMed ID: 12002442
    [Abstract] [Full Text] [Related]

  • 8. Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat.
    Bianca Rd, Wayman NS, McDonald MC, Pinto A, Shape MA, Chatterjee PK, Thiemermann C.
    Med Sci Monit; 2002 Jan 15; 8(1):BR1-7. PubMed ID: 11796957
    [Abstract] [Full Text] [Related]

  • 9. Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons.
    Pong K, Doctrow SR, Huffman K, Adinolfi CA, Baudry M.
    Exp Neurol; 2001 Sep 15; 171(1):84-97. PubMed ID: 11520123
    [Abstract] [Full Text] [Related]

  • 10. Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: effect of dietary fish oil.
    Choi-Kwon S, Park KA, Lee HJ, Park MS, Lee JH, Jeon SE, Choe MA, Park KC.
    Brain Res Dev Brain Res; 2004 Aug 18; 152(1):11-8. PubMed ID: 15283990
    [Abstract] [Full Text] [Related]

  • 11. Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury.
    Gonzalez PK, Zhuang J, Doctrow SR, Malfroy B, Benson PF, Menconi MJ, Fink MP.
    Shock; 1996 Aug 18; 6 Suppl 1():S23-6. PubMed ID: 8828094
    [Abstract] [Full Text] [Related]

  • 12. New conjugates of superoxide dismutase/catalase mimetics with cyclodestrins.
    Lanza V, Vecchio G.
    J Inorg Biochem; 2009 Mar 18; 103(3):381-8. PubMed ID: 19135258
    [Abstract] [Full Text] [Related]

  • 13. Nanoparticle-mediated delivery of superoxide dismutase to the brain: an effective strategy to reduce ischemia-reperfusion injury.
    Reddy MK, Labhasetwar V.
    FASEB J; 2009 May 18; 23(5):1384-95. PubMed ID: 19124559
    [Abstract] [Full Text] [Related]

  • 14. Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics.
    Sharpe MA, Ollosson R, Stewart VC, Clark JB.
    Biochem J; 2002 Aug 15; 366(Pt 1):97-107. PubMed ID: 11994046
    [Abstract] [Full Text] [Related]

  • 15. A novel potent radical scavenger, 8-(4-fluorophenyl)-2-((2E)-3-phenyl-2-propenoyl)-1,2,3,4-tetrahydropyrazolo[5,1-c] [1,2,4]triazine (FR210575), prevents neuronal cell death in cultured primary neurons and attenuates brain injury after focal ischemia in rats.
    Iwashita A, Maemoto T, Nakada H, Shima I, Matsuoka N, Hisajima H.
    J Pharmacol Exp Ther; 2003 Dec 15; 307(3):961-8. PubMed ID: 14534357
    [Abstract] [Full Text] [Related]

  • 16. Effect of dietary sesame oil as antioxidant on brain hippocampus of rat in focal cerebral ischemia.
    Ahmad S, Yousuf S, Ishrat T, Khan MB, Bhatia K, Fazli IS, Khan JS, Ansari NH, Islam F.
    Life Sci; 2006 Oct 12; 79(20):1921-8. PubMed ID: 16822528
    [Abstract] [Full Text] [Related]

  • 17. EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage.
    Gianello P, Saliez A, Bufkens X, Pettinger R, Misseleyn D, Hori S, Malfroy B.
    Transplantation; 1996 Dec 15; 62(11):1664-6. PubMed ID: 8970624
    [Abstract] [Full Text] [Related]

  • 18. Oxidative stress in stroke pathophysiology validation of hydrogen peroxide metabolism as a pharmacological target to afford neuroprotection.
    Amantea D, Marrone MC, Nisticò R, Federici M, Bagetta G, Bernardi G, Mercuri NB.
    Int Rev Neurobiol; 2009 Dec 15; 85():363-74. PubMed ID: 19607981
    [Abstract] [Full Text] [Related]

  • 19. Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock.
    Izumi M, McDonald MC, Sharpe MA, Chatterjee PK, Thiemermann C.
    Shock; 2002 Sep 15; 18(3):230-5. PubMed ID: 12353923
    [Abstract] [Full Text] [Related]

  • 20. Comparison of the effects of the superoxide dismutase mimetics EUK-134 and tempol on paraquat-induced nephrotoxicity.
    Samai M, Sharpe MA, Gard PR, Chatterjee PK.
    Free Radic Biol Med; 2007 Aug 15; 43(4):528-34. PubMed ID: 17640563
    [Abstract] [Full Text] [Related]

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