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Journal Abstract Search

829 related items for PubMed ID: 9435897

  • 1. Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers.
    Hu LY, Guo J, Magar SS, Fischer JB, Burke-Howie KJ, Durant GJ.
    J Med Chem; 1997 Dec 19; 40(26):4281-9. PubMed ID: 9435897
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity studies of N,N'-diarylguanidine derivatives. N-(1-naphthyl)-N'-(3-ethylphenyl)-N'-methylguanidine: a new, selective noncompetitive NMDA receptor antagonist.
    Reddy NL, Hu LY, Cotter RE, Fischer JB, Wong WJ, McBurney RN, Weber E, Holmes DL, Wong ST, Prasad R.
    J Med Chem; 1994 Jan 21; 37(2):260-7. PubMed ID: 8295213
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.
    Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1997 Feb 28; 40(5):730-8. PubMed ID: 9057859
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  • 6. Re-evaluation of phencyclidine low-affinity or "non-NMDA" binding sites.
    Hirbec H, Mausset AL, Kamenka JM, Privat A, Vignon J.
    J Neurosci Res; 2002 May 01; 68(3):305-14. PubMed ID: 12111860
    [Abstract] [Full Text] [Related]

  • 7. Interaction of L-glutamate and magnesium with phencyclidine recognition sites in rat brain: evidence for multiple affinity states of the phencyclidine/N-methyl-D-aspartate receptor complex.
    Loo PS, Braunwalder AF, Lehmann J, Williams M, Sills MA.
    Mol Pharmacol; 1987 Dec 01; 32(6):820-30. PubMed ID: 2892125
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  • 8. [Role of excitatory amino acids in neuropathology].
    Wikinski SI, Acosta GB.
    Medicina (B Aires); 1995 Dec 01; 55(4):355-65. PubMed ID: 8728878
    [Abstract] [Full Text] [Related]

  • 9. Characterization of [3H]MK-801 binding to N-methyl-D-aspartate receptors in cultured rat cerebellar granule neurons and involvement in glutamate-mediated toxicity.
    Berman FW, Murray TF.
    J Biochem Toxicol; 1996 Dec 01; 11(5):217-26. PubMed ID: 9110243
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  • 10. Synthesis and structure-activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site.
    Cai SX, Zhou ZL, Huang JC, Whittemore ER, Egbuwoku ZO, Lü Y, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1996 Aug 16; 39(17):3248-55. PubMed ID: 8765507
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and pharmacological studies at the Gly/NMDA, AMPA and Kainate receptors of new oxazolo[4,5-c]quinolin-4-one derivatives bearing different substituents at position-2 and on the fused benzo ring.
    Calabri FR, Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Costagli C, Galli A.
    Eur J Med Chem; 2005 Sep 16; 40(9):897-907. PubMed ID: 15919134
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as antagonists of the NMDA receptor-channel complex.
    Grauert M, Bechtel WD, Ensinger HA, Merz H, Carter AJ.
    J Med Chem; 1997 Aug 29; 40(18):2922-30. PubMed ID: 9288174
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  • 13. 4-substituted-3-phenylquinolin-2(1H)-ones: acidic and nonacidic glycine site N-methyl-D-aspartate antagonists with in vivo activity.
    Carling RW, Leeson PD, Moore KW, Moyes CR, Duncton M, Hudson ML, Baker R, Foster AC, Grimwood S, Kemp JA, Marshall GR, Tricklebank MD, Saywell KL.
    J Med Chem; 1997 Feb 28; 40(5):754-65. PubMed ID: 9057862
    [Abstract] [Full Text] [Related]

  • 14. Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
    Desos P, Lepagnol JM, Morain P, Lestage P, Cordi AA.
    J Med Chem; 1996 Jan 05; 39(1):197-206. PubMed ID: 8568808
    [Abstract] [Full Text] [Related]

  • 15. 5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.
    Cai SX, Huang JC, Espitia SA, Tran M, Ilyin VI, Hawkinson JE, Woodward RM, Weber E, Keana JF.
    J Med Chem; 1997 Oct 24; 40(22):3679-86. PubMed ID: 9357535
    [Abstract] [Full Text] [Related]

  • 16. L-687,414, a low efficacy NMDA receptor glycine site partial agonist in vitro, does not prevent hippocampal LTP in vivo at plasma levels known to be neuroprotective.
    Priestley T, Marshall GR, Hill RG, Kemp JA.
    Br J Pharmacol; 1998 Aug 24; 124(8):1767-73. PubMed ID: 9756395
    [Abstract] [Full Text] [Related]

  • 17. 4,5-Dihydro-1,2,4-triazolo[1,5-a]quinoxalin-4-ones: excitatory amino acid antagonists with combined glycine/NMDA and AMPA receptor affinity.
    Catarzi D, Colotta V, Varano F, Cecchi L, Filacchioni G, Galli A, Costagli C.
    J Med Chem; 1999 Jul 01; 42(13):2478-84. PubMed ID: 10395489
    [Abstract] [Full Text] [Related]

  • 18. In vitro neuroprotection by substituted guanidines with varying affinities for the N-methyl-D-aspartate receptor ionophore and for sigma sites.
    Kirk CJ, Reddy NL, Fischer JB, Wolcott TC, Knapp AG, McBurney RN.
    J Pharmacol Exp Ther; 1994 Nov 01; 271(2):1080-5. PubMed ID: 7525936
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  • 19. The NMDA receptor complex: a long and winding road to therapeutics.
    Wood PL.
    IDrugs; 2005 Mar 01; 8(3):229-35. PubMed ID: 15772895
    [Abstract] [Full Text] [Related]

  • 20. N'-3-(Trifluoromethyl)phenyl Derivatives of N-Aryl-N'-methylguanidines as Prospective PET Radioligands for the Open Channel of the N-Methyl-d-aspartate (NMDA) Receptor: Synthesis and Structure-Affinity Relationships.
    Naumiec GR, Jenko KJ, Zoghbi SS, Innis RB, Cai L, Pike VW.
    J Med Chem; 2015 Dec 24; 58(24):9722-30. PubMed ID: 26588360
    [Abstract] [Full Text] [Related]

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