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186 related items for PubMed ID: 9442032

  • 1. Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Alhonen L, Karppinen A, Uusi-Oukari M, Vujcic S, Korhonen VP, Halmekytö M, Kramer DL, Hines R, Jänne J, Porter CW.
    J Biol Chem; 1998 Jan 23; 273(4):1964-9. PubMed ID: 9442032
    [Abstract] [Full Text] [Related]

  • 2. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine.
    Alhonen L, Pietilä M, Halmekytö M, Kramer DL, Jänne J, Porter CW.
    Mol Pharmacol; 1999 Apr 23; 55(4):693-8. PubMed ID: 10101027
    [Abstract] [Full Text] [Related]

  • 3. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue.
    Suppola S, Pietilä M, Parkkinen JJ, Korhonen VP, Alhonen L, Halmekytö M, Porter CW, Jänne J.
    Biochem J; 1999 Mar 01; 338 ( Pt 2)(Pt 2):311-6. PubMed ID: 10024505
    [Abstract] [Full Text] [Related]

  • 4. Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.
    Hector S, Porter CW, Kramer DL, Clark K, Prey J, Kisiel N, Diegelman P, Chen Y, Pendyala L.
    Mol Cancer Ther; 2004 Jul 01; 3(7):813-22. PubMed ID: 15252142
    [Abstract] [Full Text] [Related]

  • 5. Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.
    Uimari A, Keinänen TA, Karppinen A, Woster P, Uimari P, Jänne J, Alhonen L.
    Biochem J; 2009 Jul 29; 422(1):101-9. PubMed ID: 19473115
    [Abstract] [Full Text] [Related]

  • 6. Overexpression of spermidine/spermine N1-acetyltransferase or treatment with N1-N11-diethylnorspermine attenuates the severity of zinc-induced pancreatitis in mouse.
    Uimari A, Merentie M, Sironen R, Pirnes-Karhu S, Peräniemi S, Alhonen L.
    Amino Acids; 2012 Feb 29; 42(2-3):461-71. PubMed ID: 21814793
    [Abstract] [Full Text] [Related]

  • 7. Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.
    Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J.
    J Cell Mol Med; 2006 Feb 29; 10(4):933-45. PubMed ID: 17125596
    [Abstract] [Full Text] [Related]

  • 8. Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.
    Tummala R, Diegelman P, Hector S, Kramer DL, Clark K, Zagst P, Fetterly G, Porter CW, Pendyala L.
    Cancer Chemother Pharmacol; 2011 Feb 29; 67(2):401-14. PubMed ID: 20443003
    [Abstract] [Full Text] [Related]

  • 9. Activation of polyamine catabolism in transgenic rats induces acute pancreatitis.
    Alhonen L, Parkkinen JJ, Keinanen T, Sinervirta R, Herzig KH, Jänne J.
    Proc Natl Acad Sci U S A; 2000 Jul 18; 97(15):8290-5. PubMed ID: 10880565
    [Abstract] [Full Text] [Related]

  • 10. Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression.
    Fogel-Petrovic M, Vujcic S, Brown PJ, Haddox MK, Porter CW.
    Biochemistry; 1996 Nov 12; 35(45):14436-44. PubMed ID: 8916930
    [Abstract] [Full Text] [Related]

  • 11. Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.
    Hector S, Tummala R, Kisiel ND, Diegelman P, Vujcic S, Clark K, Fakih M, Kramer DL, Porter CW, Pendyala L.
    Cancer Chemother Pharmacol; 2008 Aug 12; 62(3):517-27. PubMed ID: 17987291
    [Abstract] [Full Text] [Related]

  • 12. Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
    Pietilä M, Alhonen L, Halmekytö M, Kanter P, Jänne J, Porter CW.
    J Biol Chem; 1997 Jul 25; 272(30):18746-51. PubMed ID: 9228047
    [Abstract] [Full Text] [Related]

  • 13. Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues.
    Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen VP, Keinänen TA, Alhonen L, Jänne J.
    J Biol Chem; 2002 Jul 12; 277(28):25323-8. PubMed ID: 12000764
    [Abstract] [Full Text] [Related]

  • 14. Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.
    Suppola S, Heikkinen S, Parkkinen JJ, Uusi-Oukari M, Korhonen VP, Keinänen T, Alhonen L, Jänne J.
    Biochem J; 2001 Sep 01; 358(Pt 2):343-8. PubMed ID: 11513732
    [Abstract] [Full Text] [Related]

  • 15. Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase.
    Chen Y, Kramer DL, Jell J, Vujcic S, Porter CW.
    Mol Pharmacol; 2003 Nov 01; 64(5):1153-9. PubMed ID: 14573765
    [Abstract] [Full Text] [Related]

  • 16. Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine.
    Gabrielson E, Tully E, Hacker A, Pegg AE, Davidson NE, Casero RA.
    Cancer Chemother Pharmacol; 2004 Aug 01; 54(2):122-6. PubMed ID: 15138709
    [Abstract] [Full Text] [Related]

  • 17. Regulation of spermidine/spermine N1-acetyltransferase by intracellular polyamine pools. Evidence for a functional role in polyamine homeostasis.
    Shappell NW, Fogel-Petrovic MF, Porter CW.
    FEBS Lett; 1993 Apr 26; 321(2-3):179-83. PubMed ID: 8477847
    [Abstract] [Full Text] [Related]

  • 18. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells.
    Choi W, Gerner EW, Ramdas L, Dupart J, Carew J, Proctor L, Huang P, Zhang W, Hamilton SR.
    J Biol Chem; 2005 Feb 04; 280(5):3295-304. PubMed ID: 15546879
    [Abstract] [Full Text] [Related]

  • 19. Polyamine and polyamine analog regulation of spermidine/spermine N1-acetyltransferase in MALME-3M human melanoma cells.
    Fogel-Petrovic M, Shappell NW, Bergeron RJ, Porter CW.
    J Biol Chem; 1993 Sep 05; 268(25):19118-25. PubMed ID: 8360194
    [Abstract] [Full Text] [Related]

  • 20. Correlations between polyamine analogue-induced increases in spermidine/spermine N1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines.
    Porter CW, Ganis B, Libby PR, Bergeron RJ.
    Cancer Res; 1991 Jul 15; 51(14):3715-20. PubMed ID: 2065327
    [Abstract] [Full Text] [Related]

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