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Journal Abstract Search

956 related items for PubMed ID: 9443851

  • 1. Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.
    Ehlhardt WJ, Woodland JM, Baughman TM, Vandenbranden M, Wrighton SA, Kroin JS, Norman BH, Maple SR.
    Drug Metab Dispos; 1998 Jan; 26(1):42-51. PubMed ID: 9443851
    [Abstract] [Full Text] [Related]

  • 2. Metabolism and excretion of a new antianxiety drug candidate, CP-93,393, in cynomolgus monkeys: identification of the novel pyrimidine ring cleaved metabolites.
    Prakash C, Cui D.
    Drug Metab Dispos; 1997 Dec; 25(12):1395-406. PubMed ID: 9394030
    [Abstract] [Full Text] [Related]

  • 3. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
    Lenz EM, D'Souza RA, Jordan AC, King CD, Smith SM, Phillips PJ, McCormick AD, Roberts DW.
    J Pharm Biomed Anal; 2007 Feb 19; 43(3):1065-77. PubMed ID: 17030109
    [Abstract] [Full Text] [Related]

  • 4. Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS.
    Duarte IF, Legido-Quigley C, Parker DA, Swann JR, Spraul M, Braumann U, Gil AM, Holmes E, Nicholson JK, Murphy GM, Vilca-Melendez H, Heaton N, Lindon JC.
    Mol Biosyst; 2009 Feb 19; 5(2):180-90. PubMed ID: 19156264
    [Abstract] [Full Text] [Related]

  • 5. Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride.
    Teichert J, Baumann F, Chao Q, Franklin C, Bailey B, Hennig L, Caca K, Schoppmeyer K, Patzak U, Preiss R.
    Cancer Chemother Pharmacol; 2007 May 19; 59(6):759-70. PubMed ID: 16957931
    [Abstract] [Full Text] [Related]

  • 6. Biliary excretion of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) and metabolites by Fischer 344 rats.
    Musser SM, Egorin MJ, Zuhowski EG, Hamburger DR, Parise RA, Covey JM, White KD, Eiseman JL.
    Cancer Chemother Pharmacol; 2003 Aug 19; 52(2):139-46. PubMed ID: 12761648
    [Abstract] [Full Text] [Related]

  • 7. Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes.
    Edlund PO, Baranczewski P.
    J Pharm Biomed Anal; 2004 Mar 10; 34(5):1079-90. PubMed ID: 15019042
    [Abstract] [Full Text] [Related]

  • 8. Biotransformation of nevirapine, a non-nucleoside HIV-1 reverse transcriptase inhibitor, in mice, rats, rabbits, dogs, monkeys, and chimpanzees.
    Riska PS, Joseph DP, Dinallo RM, Davidson WC, Keirns JJ, Hattox SE.
    Drug Metab Dispos; 1999 Dec 10; 27(12):1434-47. PubMed ID: 10570025
    [Abstract] [Full Text] [Related]

  • 9. Application of hyphenated LC/NMR and LC/MS techniques in rapid identification of in vitro and in vivo metabolites of iloperidone.
    Mutlib AE, Strupczewski JT, Chesson SM.
    Drug Metab Dispos; 1995 Sep 10; 23(9):951-64. PubMed ID: 8565786
    [Abstract] [Full Text] [Related]

  • 10. Metabolism, pharmacokinetics, and excretion of a cholesteryl ester transfer protein inhibitor, torcetrapib, in rats, monkeys, and mice: characterization of unusual and novel metabolites by high-resolution liquid chromatography-tandem mass spectrometry and 1H nuclear magnetic resonance.
    Prakash C, Chen W, Rossulek M, Johnson K, Zhang C, O'Connell T, Potchoiba M, Dalvie D.
    Drug Metab Dispos; 2008 Oct 10; 36(10):2064-79. PubMed ID: 18653742
    [Abstract] [Full Text] [Related]

  • 11. Metabolite identification via LC-SPE-NMR-MS of the in vitro biooxidation products of a lead mGlu5 allosteric antagonist and impact on the improvement of metabolic stability in the series.
    Ceccarelli SM, Schlotterbeck G, Boissin P, Binder M, Buettelmann B, Hanlon S, Jaeschke G, Kolczewski S, Kupfer E, Peters JU, Porter RH, Prinssen EP, Rueher M, Ruf I, Spooren W, Stämpfli A, Vieira E.
    ChemMedChem; 2008 Jan 10; 3(1):136-44. PubMed ID: 17994660
    [Abstract] [Full Text] [Related]

  • 12. Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling.
    Zhang D, Wang L, Raghavan N, Zhang H, Li W, Cheng PT, Yao M, Zhang L, Zhu M, Bonacorsi S, Yeola S, Mitroka J, Hariharan N, Hosagrahara V, Chandrasena G, Shyu WC, Humphreys WG.
    Drug Metab Dispos; 2007 Jan 10; 35(1):150-67. PubMed ID: 17062777
    [Abstract] [Full Text] [Related]

  • 13. In vivo metabolism of [14C]ruboxistaurin in dogs, mice, and rats following oral administration and the structure determination of its metabolites by liquid chromatography/mass spectrometry and NMR spectroscopy.
    Barbuch RJ, Campanale K, Hadden CE, Zmijewski M, Yi P, O'Bannon DD, Burkey JL, Kulanthaivel P.
    Drug Metab Dispos; 2006 Feb 10; 34(2):213-24. PubMed ID: 16258078
    [Abstract] [Full Text] [Related]

  • 14. Metabolism and excretion of a novel antianxiety drug candidate, CP-93,393, in Long Evans rats. Differentiation of regioisomeric glucuronides by LC/MS/MS.
    Prakash C, Soliman V.
    Drug Metab Dispos; 1997 Nov 10; 25(11):1288-97. PubMed ID: 9351906
    [Abstract] [Full Text] [Related]

  • 15. Novel carbamate metabolites of mofegiline, a primary amine monoamine oxidase B inhibitor, in dogs and humans.
    Dow J, Piriou F, Wolf E, Dulery BD, Haegele KD.
    Drug Metab Dispos; 1994 Nov 10; 22(5):738-49. PubMed ID: 7835226
    [Abstract] [Full Text] [Related]

  • 16. Orally active inhibitors of human leukocyte elastase. III. Identification and characterization of metabolites of L-694,458 by liquid chromatography-tandem mass spectrometry.
    Luffer-Atlas D, Vincent SH, Painter SK, Arison BH, Stearns RA, Chiu SH.
    Drug Metab Dispos; 1997 Aug 10; 25(8):940-52. PubMed ID: 9280402
    [Abstract] [Full Text] [Related]

  • 17. Verlukast (MK-0679) conjugation with glutathione by rat liver and kidney cytosols and excretion in the bile.
    Nicoll-Griffith DA, Gupta N, Twa SP, Williams H, Trimble LA, Yergey JA.
    Drug Metab Dispos; 1995 Oct 10; 23(10):1085-93. PubMed ID: 8654196
    [Abstract] [Full Text] [Related]

  • 18. Identification of phase I metabolites of 3-methylindole produced by pig liver microsomes.
    Diaz GJ, Skordos KW, Yost GS, Squires EJ.
    Drug Metab Dispos; 1999 Oct 10; 27(10):1150-6. PubMed ID: 10497141
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of a 14C/3H-labeled GABAA receptor partial agonist in rat, dog and human liver microsomes: evaluation of a dual-radiolabel strategy.
    Shaffer CL, Langer CS.
    J Pharm Biomed Anal; 2007 Mar 12; 43(4):1195-205. PubMed ID: 17150324
    [Abstract] [Full Text] [Related]

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