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326 related items for PubMed ID: 9447969

  • 1. Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.
    Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG.
    Mol Cell Biol; 1998 Feb; 18(2):732-41. PubMed ID: 9447969
    [Abstract] [Full Text] [Related]

  • 2. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ, Ohh M, Moslehi J, Kondo K, Kaelin WG, Welch WJ.
    Mol Cell Biol; 2002 Mar; 22(6):1947-60. PubMed ID: 11865071
    [Abstract] [Full Text] [Related]

  • 3. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.
    Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD.
    Proc Natl Acad Sci U S A; 1999 Aug 17; 96(17):9533-8. PubMed ID: 10449727
    [Abstract] [Full Text] [Related]

  • 4. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
    [Abstract] [Full Text] [Related]

  • 5. Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein.
    Ohh M, Takagi Y, Aso T, Stebbins CE, Pavletich NP, Zbar B, Conaway RC, Conaway JW, Kaelin WG.
    J Clin Invest; 1999 Dec 16; 104(11):1583-91. PubMed ID: 10587522
    [Abstract] [Full Text] [Related]

  • 6. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
    Pause A, Lee S, Worrell RA, Chen DY, Burgess WH, Linehan WM, Klausner RD.
    Proc Natl Acad Sci U S A; 1997 Mar 18; 94(6):2156-61. PubMed ID: 9122164
    [Abstract] [Full Text] [Related]

  • 7. The von Hippel-Lindau tumour suppressor protein: new perspectives.
    Ohh M, Kaelin WG.
    Mol Med Today; 1999 Jun 18; 5(6):257-63. PubMed ID: 10366821
    [Abstract] [Full Text] [Related]

  • 8. Functions of the von Hippel-Lindau tumour suppressor protein.
    Kaelin WG, Iliopoulos O, Lonergan KM, Ohh M.
    J Intern Med; 1998 Jun 18; 243(6):535-9. PubMed ID: 9681855
    [Abstract] [Full Text] [Related]

  • 9. The von Hippel-Lindau tumor suppressor protein.
    Ivan M, Kaelin WG.
    Curr Opin Genet Dev; 2001 Feb 18; 11(1):27-34. PubMed ID: 11163147
    [Abstract] [Full Text] [Related]

  • 10. Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product.
    Tsuchiya H, Iseda T, Hino O.
    Cancer Res; 1996 Jul 01; 56(13):2881-5. PubMed ID: 8674032
    [Abstract] [Full Text] [Related]

  • 11. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
    Mahrour N, Redwine WB, Florens L, Swanson SK, Martin-Brown S, Bradford WD, Staehling-Hampton K, Washburn MP, Conaway RC, Conaway JW.
    J Biol Chem; 2008 Mar 21; 283(12):8005-13. PubMed ID: 18187417
    [Abstract] [Full Text] [Related]

  • 12. Identification of Elongin C and Skp1 sequences that determine Cullin selection.
    Yan Q, Kamura T, Cai Y, Jin J, Ivan M, Mushegian A, Conaway RC, Conaway JW.
    J Biol Chem; 2004 Oct 08; 279(41):43019-26. PubMed ID: 15280393
    [Abstract] [Full Text] [Related]

  • 13. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
    Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC.
    Proc Natl Acad Sci U S A; 2002 Aug 06; 99(16):10353-8. PubMed ID: 12149480
    [Abstract] [Full Text] [Related]

  • 14. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
    Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW.
    Genes Dev; 1999 Nov 15; 13(22):2928-33. PubMed ID: 10579999
    [Abstract] [Full Text] [Related]

  • 15. The von Hippel-Lindau protein interacts with heteronuclear ribonucleoprotein a2 and regulates its expression.
    Pioli PA, Rigby WF.
    J Biol Chem; 2001 Oct 26; 276(43):40346-52. PubMed ID: 11517223
    [Abstract] [Full Text] [Related]

  • 16. von Hippel-Lindau protein induces hypoxia-regulated arrest of tyrosine hydroxylase transcript elongation in pheochromocytoma cells.
    Kroll SL, Paulding WR, Schnell PO, Barton MC, Conaway JW, Conaway RC, Czyzyk-Krzeska MF.
    J Biol Chem; 1999 Oct 15; 274(42):30109-14. PubMed ID: 10514498
    [Abstract] [Full Text] [Related]

  • 17. Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity.
    Blankenship C, Naglich JG, Whaley JM, Seizinger B, Kley N.
    Oncogene; 1999 Feb 25; 18(8):1529-35. PubMed ID: 10102622
    [Abstract] [Full Text] [Related]

  • 18. The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
    Wada H, Yeh ET, Kamitani T.
    J Biol Chem; 1999 Dec 10; 274(50):36025-9. PubMed ID: 10585493
    [Abstract] [Full Text] [Related]

  • 19. Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C.
    Kibel A, Iliopoulos O, DeCaprio JA, Kaelin WG.
    Science; 1995 Sep 08; 269(5229):1444-6. PubMed ID: 7660130
    [Abstract] [Full Text] [Related]

  • 20. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
    Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A.
    Proc Natl Acad Sci U S A; 1999 Oct 26; 96(22):12436-41. PubMed ID: 10535940
    [Abstract] [Full Text] [Related]

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