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815 related items for PubMed ID: 9466577

  • 1. Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha.
    Gerritsen ME, Shen CP, Perry CA.
    Am J Pathol; 1998 Feb; 152(2):505-12. PubMed ID: 9466577
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of ceramide pathway does not affect ability of TNF-alpha to activate nuclear factor-kappa B.
    Johns LD, Sarr T, Ranges GE.
    J Immunol; 1994 Jun 15; 152(12):5877-82. PubMed ID: 8207213
    [Abstract] [Full Text] [Related]

  • 3. Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation.
    Higuchi M, Singh S, Jaffrezou JP, Aggarwal BB.
    J Immunol; 1996 Jul 01; 157(1):297-304. PubMed ID: 8683130
    [Abstract] [Full Text] [Related]

  • 4. Abnormal nuclear factor (NF)-kappaB signal pathway and aspirin inhibits tumor necrosis factor alpha-induced NF-kappaB activation in keloid fibroblasts.
    Zhu G, Cai J, Zhang J, Zhao Y, Xu B.
    Dermatol Surg; 2007 Jun 01; 33(6):697-708. PubMed ID: 17550447
    [Abstract] [Full Text] [Related]

  • 5. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.
    Oncogene; 2007 Feb 22; 26(8):1201-12. PubMed ID: 16924232
    [Abstract] [Full Text] [Related]

  • 6. Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells.
    Kimura K, Markowski M, Edsall LC, Spiegel S, Gelmann EP.
    Cell Death Differ; 2003 Feb 22; 10(2):240-8. PubMed ID: 12700652
    [Abstract] [Full Text] [Related]

  • 7. TNFR1-induced sphingomyelinase activation modulates TCR signaling by impairing store-operated Ca2+ influx.
    Church LD, Hessler G, Goodall JE, Rider DA, Workman CJ, Vignali DA, Bacon PA, Gulbins E, Young SP.
    J Leukoc Biol; 2005 Jul 22; 78(1):266-78. PubMed ID: 15817701
    [Abstract] [Full Text] [Related]

  • 8. Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts.
    Payne SG, Brindley DN, Guilbert LJ.
    J Cell Physiol; 1999 Aug 22; 180(2):263-70. PubMed ID: 10395296
    [Abstract] [Full Text] [Related]

  • 9. Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.
    Tellier E, Nègre-Salvayre A, Bocquet B, Itohara S, Hannun YA, Salvayre R, Augé N.
    Mol Cell Biol; 2007 Apr 22; 27(8):2997-3007. PubMed ID: 17283058
    [Abstract] [Full Text] [Related]

  • 10. Role for matrix metalloproteinase-2 in oxidized low-density lipoprotein-induced activation of the sphingomyelin/ceramide pathway and smooth muscle cell proliferation.
    Augé N, Maupas-Schwalm F, Elbaz M, Thiers JC, Waysbort A, Itohara S, Krell HW, Salvayre R, Nègre-Salvayre A.
    Circulation; 2004 Aug 03; 110(5):571-8. PubMed ID: 15277330
    [Abstract] [Full Text] [Related]

  • 11. Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.
    Xu H, He Y, Yang X, Liang L, Zhan Z, Ye Y, Yang X, Lian F, Sun L.
    Rheumatology (Oxford); 2007 Jun 03; 46(6):920-6. PubMed ID: 17314215
    [Abstract] [Full Text] [Related]

  • 12. NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis.
    Bai S, Liu H, Chen KH, Eksarko P, Perlman H, Moore TL, Pope RM.
    Arthritis Rheum; 2004 Dec 03; 50(12):3844-55. PubMed ID: 15593196
    [Abstract] [Full Text] [Related]

  • 13. Androgen blocks apoptosis of hormone-dependent prostate cancer cells.
    Kimura K, Markowski M, Bowen C, Gelmann EP.
    Cancer Res; 2001 Jul 15; 61(14):5611-8. PubMed ID: 11454715
    [Abstract] [Full Text] [Related]

  • 14. Distinct effects of ceramide-generating pathways in prostate adenocarcinoma cells.
    Condorelli F, Canonico PL, Sortino MA.
    Br J Pharmacol; 1999 May 15; 127(1):75-84. PubMed ID: 10369458
    [Abstract] [Full Text] [Related]

  • 15. Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis.
    Kimura K, Bowen C, Spiegel S, Gelmann EP.
    Cancer Res; 1999 Apr 01; 59(7):1606-14. PubMed ID: 10197636
    [Abstract] [Full Text] [Related]

  • 16. Modulation of TNF-alpha-induced apoptosis in corneal fibroblasts by transcription factor NF-kappaB.
    Mohan RR, Mohan RR, Kim WJ, Wilson SE.
    Invest Ophthalmol Vis Sci; 2000 May 01; 41(6):1327-36. PubMed ID: 10798647
    [Abstract] [Full Text] [Related]

  • 17. The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin.
    Mansat V, Laurent G, Levade T, Bettaïeb A, Jaffrézou JP.
    Cancer Res; 1997 Dec 01; 57(23):5300-4. PubMed ID: 9393753
    [Abstract] [Full Text] [Related]

  • 18. Gene therapy that inhibits nuclear translocation of nuclear factor kappaB results in tumor necrosis factor alpha-induced apoptosis of human synovial fibroblasts.
    Zhang HG, Huang N, Liu D, Bilbao L, Zhang X, Yang P, Zhou T, Curiel DT, Mountz JD.
    Arthritis Rheum; 2000 May 01; 43(5):1094-105. PubMed ID: 10817564
    [Abstract] [Full Text] [Related]

  • 19. Endothelial nitric oxide synthase activation by tumor necrosis factor alpha through neutral sphingomyelinase 2, sphingosine kinase 1, and sphingosine 1 phosphate receptors: a novel pathway relevant to the pathophysiology of endothelium.
    De Palma C, Meacci E, Perrotta C, Bruni P, Clementi E.
    Arterioscler Thromb Vasc Biol; 2006 Jan 01; 26(1):99-105. PubMed ID: 16269668
    [Abstract] [Full Text] [Related]

  • 20. Sphingomyelin-ceramide turnover in CD28 costimulatory signaling.
    Chan G, Ochi A.
    Eur J Immunol; 1995 Jul 01; 25(7):1999-2004. PubMed ID: 7621875
    [Abstract] [Full Text] [Related]

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