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Journal Abstract Search

621 related items for PubMed ID: 9466980

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  • 2. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.
    Iyer L, Hall D, Das S, Mortell MA, Ramírez J, Kim S, Di Rienzo A, Ratain MJ.
    Clin Pharmacol Ther; 1999 May; 65(5):576-82. PubMed ID: 10340924
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  • 4. Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).
    Gagné JF, Montminy V, Belanger P, Journault K, Gaucher G, Guillemette C.
    Mol Pharmacol; 2002 Sep; 62(3):608-17. PubMed ID: 12181437
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  • 6. Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats.
    Onoue M, Kurita A, Kado S, Matsumoto T, Kaneda N, Uchida K, Kato I, Yokokura T.
    Cancer Chemother Pharmacol; 2008 Apr; 61(4):595-605. PubMed ID: 17549477
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  • 7. UGT1A10 is responsible for SN-38 glucuronidation and its expression in human lung cancers.
    Oguri T, Takahashi T, Miyazaki M, Isobe T, Kohno N, Mackenzie PI, Fujiwara Y.
    Anticancer Res; 2004 Apr; 24(5A):2893-6. PubMed ID: 15517893
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  • 8. Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
    Jinno H, Tanaka-Kagawa T, Hanioka N, Saeki M, Ishida S, Nishimura T, Ando M, Saito Y, Ozawa S, Sawada J.
    Drug Metab Dispos; 2003 Jan; 31(1):108-13. PubMed ID: 12485959
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  • 9. The contribution of intestinal UDP-glucuronosyltransferases in modulating 7-ethyl-10-hydroxy-camptothecin (SN-38)-induced gastrointestinal toxicity in rats.
    Tallman MN, Miles KK, Kessler FK, Nielsen JN, Tian X, Ritter JK, Smith PC.
    J Pharmacol Exp Ther; 2007 Jan; 320(1):29-37. PubMed ID: 17003228
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  • 12. The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.
    Liu Y, Ramírez J, House L, Ratain MJ.
    Eur J Cancer; 2010 Jul; 46(11):2097-103. PubMed ID: 20580994
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  • 14. Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
    Yong WP, Ramirez J, Innocenti F, Ratain MJ.
    Clin Cancer Res; 2005 Sep 15; 11(18):6699-704. PubMed ID: 16166450
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  • 17. Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.
    Innocenti F, Iyer L, Ratain MJ.
    Drug Metab Dispos; 2001 Apr 15; 29(4 Pt 2):596-600. PubMed ID: 11259359
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  • 19. Irinotecan treatment in cancer patients with UGT1A1 polymorphisms.
    Innocenti F, Ratain MJ.
    Oncology (Williston Park); 2003 May 15; 17(5 Suppl 5):52-5. PubMed ID: 12800608
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  • 20. Severe irinotecan-induced toxicities in a patient with uridine diphosphate glucuronosyltransferase 1A1 polymorphism.
    Mehra R, Murren J, Chung G, Smith B, Psyrri A.
    Clin Colorectal Cancer; 2005 May 15; 5(1):61-4. PubMed ID: 15929808
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