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217 related items for PubMed ID: 9469584

  • 1. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 2. Regulation of cholesterol biosynthetic pathway in patients with the Smith-Lemli-Opitz syndrome.
    Honda M, Tint GS, Honda A, Salen G, Shefer S, Batta AK, Matsuzaki Y, Tanaka N.
    J Inherit Metab Dis; 2000 Jul; 23(5):464-74. PubMed ID: 10947201
    [Abstract] [Full Text] [Related]

  • 3. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 4. Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities.
    Honda A, Salen G, Nguyen LB, Xu G, Tint GS, Batta AK, Shefer S.
    Hepatology; 1998 Jan; 27(1):154-9. PubMed ID: 9425931
    [Abstract] [Full Text] [Related]

  • 5. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 6. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

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  • 8. Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities.
    Balasubramaniam S, Goldstein JL, Brown MS.
    Proc Natl Acad Sci U S A; 1977 Apr; 74(4):1421-5. PubMed ID: 16260
    [Abstract] [Full Text] [Related]

  • 9. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 10. Sitosterolemia: exclusion of genes involved in reduced cholesterol biosynthesis.
    Patel SB, Honda A, Salen G.
    J Lipid Res; 1998 May; 39(5):1055-61. PubMed ID: 9610773
    [Abstract] [Full Text] [Related]

  • 11. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 12. Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin.
    Nguyen L, Salen G, Shefer S, Shore V, Tint GS, Ness G.
    Arteriosclerosis; 1990 Dec; 10(2):289-97. PubMed ID: 2317163
    [Abstract] [Full Text] [Related]

  • 13. Stimulation of hepatic cholesterol biosynthesis by fatty acids. Effects of oleate on cytoplasmic acetoacetyl-CoA thiolase, acetoacetyl-CoA synthetase and hydroxymethylglutaryl-CoA synthase.
    Salam WH, Wilcox HG, Cagen LM, Heimberg M.
    Biochem J; 1989 Mar 01; 258(2):563-8. PubMed ID: 2565110
    [Abstract] [Full Text] [Related]

  • 14. Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.
    Cohen LH, van Vliet A, Roodenburg L, Jansen LM, Griffioen M.
    Biochem Pharmacol; 1993 Jun 09; 45(11):2203-8. PubMed ID: 8517861
    [Abstract] [Full Text] [Related]

  • 15. Inhibitors of sterol synthesis. Effects of dietary 5 alpha-cholest-8(14)-en-3 beta-ol-15-one on early enzymes in hepatic cholesterol biosynthesis.
    Miller LR, Raulston DL, Schroepfer GJ.
    Chem Phys Lipids; 1988 Jul 09; 47(3):177-86. PubMed ID: 2901919
    [Abstract] [Full Text] [Related]

  • 16. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul 09; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 17. Regulation of hepatic cholesterol biosynthesis by fatty acids: effect of feeding olive oil on cytoplasmic acetoacetyl-coenzyme A thiolase, beta-hydroxy-beta-methylglutaryl-CoA synthase, and acetoacetyl-coenzyme A ligase.
    Salam WH, Cagen LM, Heimberg M.
    Biochem Biophys Res Commun; 1988 May 31; 153(1):422-7. PubMed ID: 2897853
    [Abstract] [Full Text] [Related]

  • 18. Sterol-independent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase by mevalonate in Chinese hamster ovary cells. Magnitude and specificity.
    Panini SR, Schnitzer-Polokoff R, Spencer TA, Sinensky M.
    J Biol Chem; 1989 Jul 05; 264(19):11044-52. PubMed ID: 2567731
    [Abstract] [Full Text] [Related]

  • 19. Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver.
    Powell EE, Kroon PA.
    J Clin Invest; 1994 May 05; 93(5):2168-74. PubMed ID: 8182149
    [Abstract] [Full Text] [Related]

  • 20. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep 05; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

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