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Journal Abstract Search

135 related items for PubMed ID: 9485016

  • 1. Alpha-hydroxytamoxifen is a substrate of hydroxysteroid (alcohol) sulfotransferase, resulting in tamoxifen DNA adducts.
    Shibutani S, Dasaradhi L, Terashima I, Banoglu E, Duffel MW.
    Cancer Res; 1998 Feb 15; 58(4):647-53. PubMed ID: 9485016
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  • 2. Sulfation of alpha-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts.
    Shibutani S, Shaw PM, Suzuki N, Dasaradhi L, Duffel MW, Terashima I.
    Carcinogenesis; 1998 Nov 15; 19(11):2007-11. PubMed ID: 9855017
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  • 3. Interactions of the stereoisomers of alpha-hydroxytamoxifen with human hydroxysteroid sulfotransferase SULT2A1 and rat hydroxysteroid sulfotransferase STa.
    Apak TI, Duffel MW.
    Drug Metab Dispos; 2004 Dec 15; 32(12):1501-8. PubMed ID: 15371299
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  • 4. Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of alpha-hydroxytamoxifen in rat and human livers.
    Kim SY, Laxmi YR, Suzuki N, Ogura K, Watabe T, Duffel MW, Shibutani S.
    Drug Metab Dispos; 2005 Nov 15; 33(11):1673-8. PubMed ID: 16099924
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  • 5. Formation of tamoxifen-DNA adducts in human endometrial explants exposed to alpha-hydroxytamoxifen.
    Kim SY, Suzuki N, Laxmi YR, McGarrigle BP, Olson JR, Sharma M, Sharma M, Shibutani S.
    Chem Res Toxicol; 2005 May 15; 18(5):889-95. PubMed ID: 15892583
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  • 6. Identification of hepatic tamoxifen-DNA adducts in mice: alpha-(N(2)-deoxyguanosinyl)tamoxifen and alpha-(N(2)-deoxyguanosinyl)tamoxifen N-oxide.
    Umemoto A, Monden Y, Suwa M, Kanno Y, Suzuki M, Lin CX, Ueyama Y, Momen MA, Ravindernath A, Shibutani S, Komaki K.
    Carcinogenesis; 2000 Sep 15; 21(9):1737-44. PubMed ID: 10964106
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  • 8. Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts.
    Boocock DJ, Maggs JL, Brown K, White IN, Park BK.
    Carcinogenesis; 2000 Oct 15; 21(10):1851-8. PubMed ID: 11023543
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  • 9. Mechanism of lower genotoxicity of toremifene compared with tamoxifen.
    Shibutani S, Ravindernath A, Terashima I, Suzuki N, Laxmi YR, Kanno Y, Suzuki M, Apak TI, Sheng JJ, Duffel MW.
    Cancer Res; 2001 May 15; 61(10):3925-31. PubMed ID: 11358807
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  • 12. Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen.
    Pathak DN, Pongracz K, Bodell WJ.
    Carcinogenesis; 1996 Sep 15; 17(9):1785-90. PubMed ID: 8824496
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  • 14. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
    Randerath K, Moorthy B, Mabon N, Sriram P.
    Carcinogenesis; 1994 Oct 15; 15(10):2087-94. PubMed ID: 7955037
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  • 15. Identification of tamoxifen-DNA adducts formed by alpha-sulfate tamoxifen and alpha-acetoxytamoxifen.
    Dasaradhi L, Shibutani S.
    Chem Res Toxicol; 1997 Feb 15; 10(2):189-96. PubMed ID: 9049430
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  • 16. Tamoxifen-DNA adduct formation in rat liver determined by immunoassay and 32P-postlabeling.
    Divi RL, Osborne MR, Hewer A, Phillips DH, Poirier MC.
    Cancer Res; 1999 Oct 01; 59(19):4829-33. PubMed ID: 10519392
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