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280 related items for PubMed ID: 9485477

  • 1. Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1.
    Landgraf R, Pegram M, Slamon DJ, Eisenberg D.
    Biochemistry; 1998 Mar 03; 37(9):3220-8. PubMed ID: 9485477
    [Abstract] [Full Text] [Related]

  • 2. Gamma-heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175.
    Schaefer G, Fitzpatrick VD, Sliwkowski MX.
    Oncogene; 1997 Sep 18; 15(12):1385-94. PubMed ID: 9333014
    [Abstract] [Full Text] [Related]

  • 3. Recombinant heregulin-Pseudomonas exotoxin fusion proteins: interactions with the heregulin receptors and antitumor activity in vivo.
    Yang D, Kuan CT, Payne J, Kihara A, Murray A, Wang LM, Alimandi M, Pierce JH, Pastan I, Lippman ME.
    Clin Cancer Res; 1998 Apr 18; 4(4):993-1004. PubMed ID: 9563895
    [Abstract] [Full Text] [Related]

  • 4. Distinct characteristics of heregulin signals mediated by HER3 or HER4.
    Weiss FU, Wallasch C, Campiglio M, Issing W, Ullrich A.
    J Cell Physiol; 1997 Nov 18; 173(2):187-95. PubMed ID: 9365520
    [Abstract] [Full Text] [Related]

  • 5. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.
    Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX.
    Cancer Res; 1996 Mar 15; 56(6):1457-65. PubMed ID: 8640840
    [Abstract] [Full Text] [Related]

  • 6. Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2.
    Jhabvala-Romero F, Evans A, Guo S, Denton M, Clinton GM.
    Oncogene; 2003 Nov 06; 22(50):8178-86. PubMed ID: 14603258
    [Abstract] [Full Text] [Related]

  • 7. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase.
    Tan M, Grijalva R, Yu D.
    Cancer Res; 1999 Apr 01; 59(7):1620-5. PubMed ID: 10197638
    [Abstract] [Full Text] [Related]

  • 8. Heregulin-dependent autocrine loop regulates growth of K-ras but not erbB-2 transformed rat thyroid epithelial cells.
    Mincione G, Piccirelli A, Lazzereschi D, Salomon DS, Colletta G.
    J Cell Physiol; 1998 Aug 01; 176(2):383-91. PubMed ID: 9648926
    [Abstract] [Full Text] [Related]

  • 9. Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells.
    Ram TG, Hosick HL, Ethier SP.
    J Cell Physiol; 2000 Jun 01; 183(3):301-13. PubMed ID: 10797304
    [Abstract] [Full Text] [Related]

  • 10. Characteristics of EGFR family-mediated HRG signals in human ovarian cancer.
    Campiglio M, Ali S, Knyazev PG, Ullrich A.
    J Cell Biochem; 1999 Jun 15; 73(4):522-32. PubMed ID: 10733345
    [Abstract] [Full Text] [Related]

  • 11. Heregulin degradation in the absence of rapid receptor-mediated internalization.
    Baulida J, Carpenter G.
    Exp Cell Res; 1997 Apr 10; 232(1):167-72. PubMed ID: 9141633
    [Abstract] [Full Text] [Related]

  • 12. Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
    Belsches-Jablonski AP, Biscardi JS, Peavy DR, Tice DA, Romney DA, Parsons SJ.
    Oncogene; 2001 Mar 22; 20(12):1465-75. PubMed ID: 11313890
    [Abstract] [Full Text] [Related]

  • 13. The EGF receptor binding of recombinant heregulinbeta1/EGF hybrids is blocked by heregulin residue glutamate 195.
    Chau BN, Nandagopal K, Niyogi SK, Campion SR.
    Biochem Biophys Res Commun; 1996 Dec 24; 229(3):882-6. PubMed ID: 8954988
    [Abstract] [Full Text] [Related]

  • 14. The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression.
    Xu F, Yu Y, Le XF, Boyer C, Mills GB, Bast RC.
    Clin Cancer Res; 1999 Nov 24; 5(11):3653-60. PubMed ID: 10589783
    [Abstract] [Full Text] [Related]

  • 15. Induction of sensitivity to doxorubicin and etoposide by transfection of MCF-7 breast cancer cells with heregulin beta-2.
    Harris LN, Yang L, Tang C, Yang D, Lupu R.
    Clin Cancer Res; 1998 Apr 24; 4(4):1005-12. PubMed ID: 9563896
    [Abstract] [Full Text] [Related]

  • 16. Targeted inhibition of tumor-cell growth by recombinant heregulin-toxin fusion proteins.
    Jeschke M, Wels W, Dengler W, Imber R, Stöcklin E, Groner B.
    Int J Cancer; 1995 Mar 03; 60(5):730-9. PubMed ID: 7860149
    [Abstract] [Full Text] [Related]

  • 17. Study of inhibition effect of herceptin on interaction between heregulin and erbB receptors HER3/HER2 by single-molecule force spectroscopy.
    Shi X, Xu L, Yu J, Fang X.
    Exp Cell Res; 2009 Oct 01; 315(16):2847-55. PubMed ID: 19497323
    [Abstract] [Full Text] [Related]

  • 18. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification.
    Ram TG, Ethier SP.
    Cell Growth Differ; 1996 May 01; 7(5):551-61. PubMed ID: 8732665
    [Abstract] [Full Text] [Related]

  • 19. Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells.
    Sepp-Lorenzino L, Eberhard I, Ma Z, Cho C, Serve H, Liu F, Rosen N, Lupu R.
    Oncogene; 1996 Apr 18; 12(8):1679-87. PubMed ID: 8622888
    [Abstract] [Full Text] [Related]

  • 20. Mitogenic activity of neu differentiation factor/heregulin mimics that of epidermal growth factor and insulin-like growth factor-I in human mammary epithelial cells.
    Ram TG, Kokeny KE, Dilts CA, Ethier SP.
    J Cell Physiol; 1995 Jun 18; 163(3):589-96. PubMed ID: 7775601
    [Abstract] [Full Text] [Related]

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