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622 related items for PubMed ID: 9486667

  • 1. Molecular determinants of dofetilide block of HERG K+ channels.
    Ficker E, Jarolimek W, Kiehn J, Baumann A, Brown AM.
    Circ Res; 1998 Feb 23; 82(3):386-95. PubMed ID: 9486667
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  • 3. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.
    Kiehn J, Lacerda AE, Wible B, Brown AM.
    Circulation; 1996 Nov 15; 94(10):2572-9. PubMed ID: 8921803
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  • 5. High affinity open channel block by dofetilide of HERG expressed in a human cell line.
    Snyders DJ, Chaudhary A.
    Mol Pharmacol; 1996 Jun 15; 49(6):949-55. PubMed ID: 8649354
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  • 6. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
    Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J.
    J Pharmacol Exp Ther; 2001 May 15; 297(2):753-61. PubMed ID: 11303067
    [Abstract] [Full Text] [Related]

  • 7. Dofetilide block involves interactions with open and inactivated states of HERG channels.
    Weerapura M, Hébert TE, Nattel S.
    Pflugers Arch; 2002 Feb 15; 443(4):520-31. PubMed ID: 11907818
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  • 8. Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels.
    Park JB, Choe H, Lee YK, Ha KC, Rhee KS, Ko JK, Joo CU, Chae SW, Kwak YG.
    J Pharmacol Exp Ther; 2002 Jul 15; 302(1):314-9. PubMed ID: 12065732
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels.
    Kiehn J, Thomas D, Karle CA, Schöls W, Kübler W.
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Mar 15; 359(3):212-9. PubMed ID: 10208308
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  • 10. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
    Dong DL, Li Z, Wang HZ, Du ZM, Song WH, Yang BF.
    Basic Clin Pharmacol Toxicol; 2004 May 15; 94(5):209-12. PubMed ID: 15125690
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  • 11. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides.
    Spector PS, Curran ME, Keating MT, Sanguinetti MC.
    Circ Res; 1996 Mar 15; 78(3):499-503. PubMed ID: 8593709
    [Abstract] [Full Text] [Related]

  • 12. [3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel?
    Finlayson K, Pennington AJ, Kelly JS.
    Eur J Pharmacol; 2001 Feb 02; 412(3):203-12. PubMed ID: 11166283
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  • 13. Open channel block of HERG K(+) channels by vesnarinone.
    Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC.
    Mol Pharmacol; 2001 Aug 02; 60(2):244-53. PubMed ID: 11455010
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  • 14. Specific block of cloned Herg channels by clofilium and its tertiary analog LY97241.
    Suessbrich H, Schönherr R, Heinemann SH, Lang F, Busch AE.
    FEBS Lett; 1997 Sep 08; 414(2):435-8. PubMed ID: 9315735
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  • 15. The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o.
    Diaz GJ, Daniell K, Leitza ST, Martin RL, Su Z, McDermott JS, Cox BF, Gintant GA.
    J Pharmacol Toxicol Methods; 2004 Sep 08; 50(3):187-99. PubMed ID: 15519905
    [Abstract] [Full Text] [Related]

  • 16. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D, Roy ML, Dennis A, Brown AM.
    FEBS Lett; 1997 Nov 03; 417(1):28-32. PubMed ID: 9395068
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  • 17. Redox state dependency of HERGS631C channel pharmacology: relation to C-type inactivation.
    Ulens C, Tytgat J.
    FEBS Lett; 2000 May 26; 474(1):111-5. PubMed ID: 10828461
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  • 18. Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
    Sanguinetti MC, Xu QP.
    J Physiol; 1999 Feb 01; 514 ( Pt 3)(Pt 3):667-75. PubMed ID: 9882738
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  • 19. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels.
    Chen J, Seebohm G, Sanguinetti MC.
    Proc Natl Acad Sci U S A; 2002 Sep 17; 99(19):12461-6. PubMed ID: 12209010
    [Abstract] [Full Text] [Related]

  • 20. Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels.
    Herzberg IM, Trudeau MC, Robertson GA.
    J Physiol; 1998 Aug 15; 511 ( Pt 1)(Pt 1):3-14. PubMed ID: 9679158
    [Abstract] [Full Text] [Related]

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