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Journal Abstract Search

597 related items for PubMed ID: 9492390

  • 1. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M, Inoue T, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y.
    Drug Metab Dispos; 1998 Mar; 26(3):261-6. PubMed ID: 9492390
    [Abstract] [Full Text] [Related]

  • 2. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 3. Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach.
    Venkatakrishnan K, von Moltke LL, Greenblatt DJ.
    J Pharm Sci; 1998 Jul 01; 87(7):845-53. PubMed ID: 9649353
    [Abstract] [Full Text] [Related]

  • 4. Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro.
    Störmer E, Brockmöller J, Roots I, Schmider J.
    Psychopharmacology (Berl); 2000 Sep 01; 151(4):312-20. PubMed ID: 11026737
    [Abstract] [Full Text] [Related]

  • 5. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X, Wang JS, Kivistö KT, Neuvonen PJ, Backman JT.
    Br J Clin Pharmacol; 2001 Nov 01; 52(5):547-53. PubMed ID: 11736863
    [Abstract] [Full Text] [Related]

  • 6. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Schmider J, Harmatz JS, Shader RI.
    J Pharm Pharmacol; 1998 Sep 01; 50(9):997-1004. PubMed ID: 9811160
    [Abstract] [Full Text] [Related]

  • 7. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
    Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.
    Eur J Clin Pharmacol; 2001 Apr 01; 57(1):31-6. PubMed ID: 11372587
    [Abstract] [Full Text] [Related]

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  • 9. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K, Konishi T, Nishikawa H, Kitamura S.
    Xenobiotica; 1999 Sep 01; 29(9):899-907. PubMed ID: 10548450
    [Abstract] [Full Text] [Related]

  • 10. Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen.
    Miners JO, Coulter S, Tukey RH, Veronese ME, Birkett DJ.
    Biochem Pharmacol; 1996 Apr 26; 51(8):1003-8. PubMed ID: 8866821
    [Abstract] [Full Text] [Related]

  • 11. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K, von Moltke LL, Duan SX, Fleishaker JC, Shader RI, Greenblatt DJ.
    J Pharm Pharmacol; 1998 Mar 26; 50(3):265-74. PubMed ID: 9600717
    [Abstract] [Full Text] [Related]

  • 12. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM, Kupfer D.
    Drug Metab Dispos; 1998 Sep 26; 26(9):868-74. PubMed ID: 9733665
    [Abstract] [Full Text] [Related]

  • 13. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 26; 28(3):354-9. PubMed ID: 10681382
    [Abstract] [Full Text] [Related]

  • 14. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM, Verhoeven CH, Shimada T, Back DJ.
    J Pharmacol Exp Ther; 1998 Dec 26; 287(3):975-82. PubMed ID: 9864282
    [Abstract] [Full Text] [Related]

  • 15. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD, Kukulka MJ, Roberts EM, Ouellet D, Rodgers TR.
    Drug Metab Dispos; 1996 Jan 26; 24(1):126-36. PubMed ID: 8825200
    [Abstract] [Full Text] [Related]

  • 16. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 17. Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations.
    Inoue K, Yamazaki H, Imiya K, Akasaka S, Guengerich FP, Shimada T.
    Pharmacogenetics; 1997 Apr 01; 7(2):103-13. PubMed ID: 9170147
    [Abstract] [Full Text] [Related]

  • 18. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.
    Xu ZH, Wang W, Zhao XJ, Huang SL, Zhu B, He N, Shu Y, Liu ZQ, Zhou HH.
    Br J Clin Pharmacol; 1999 Sep 01; 48(3):416-23. PubMed ID: 10510155
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct 01; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 20. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb 01; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

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