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Journal Abstract Search


217 related items for PubMed ID: 9493314

  • 1. Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4.
    Chesné C, Guyomard C, Guillouzo A, Schmid J, Ludwig E, Sauter T.
    Xenobiotica; 1998 Jan; 28(1):1-13. PubMed ID: 9493314
    [Abstract] [Full Text] [Related]

  • 2. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 3. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K, Konishi T, Nishikawa H, Kitamura S.
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [Abstract] [Full Text] [Related]

  • 4. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K, von Moltke LL, Duan SX, Fleishaker JC, Shader RI, Greenblatt DJ.
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [Abstract] [Full Text] [Related]

  • 5. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 6. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 7. Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes.
    Yamazaki H, Shibata A, Suzuki M, Nakajima M, Shimada N, Guengerich FP, Yokoi T.
    Drug Metab Dispos; 1999 Nov 01; 27(11):1260-6. PubMed ID: 10534310
    [Abstract] [Full Text] [Related]

  • 8. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.
    J Pharmacol Exp Ther; 2000 May 01; 293(2):453-9. PubMed ID: 10773015
    [Abstract] [Full Text] [Related]

  • 9. Effects of propofol on human hepatic microsomal cytochrome P450 activities.
    McKillop D, Wild MJ, Butters CJ, Simcock C.
    Xenobiotica; 1998 Sep 01; 28(9):845-53. PubMed ID: 9764927
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M, Inoue T, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y.
    Drug Metab Dispos; 1998 Mar 01; 26(3):261-6. PubMed ID: 9492390
    [Abstract] [Full Text] [Related]

  • 11. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R, Roe EG, Jones BC, Smith DA.
    Br J Clin Pharmacol; 2001 Mar 01; 51(3):239-48. PubMed ID: 11298070
    [Abstract] [Full Text] [Related]

  • 12. Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes.
    Crewe HK, Ellis SW, Lennard MS, Tucker GT.
    Biochem Pharmacol; 1997 Jan 24; 53(2):171-8. PubMed ID: 9037249
    [Abstract] [Full Text] [Related]

  • 13. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM, Verhoeven CH, Shimada T, Back DJ.
    J Pharmacol Exp Ther; 1998 Dec 24; 287(3):975-82. PubMed ID: 9864282
    [Abstract] [Full Text] [Related]

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  • 16. 16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.
    Huang Z, Guengerich FP, Kaminsky LS.
    Carcinogenesis; 1998 May 24; 19(5):867-72. PubMed ID: 9635876
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
    Feierman DE, Lasker JM.
    Drug Metab Dispos; 1996 Sep 24; 24(9):932-9. PubMed ID: 8886601
    [Abstract] [Full Text] [Related]

  • 18. Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5'-methylhydroxylation by quinidine and hydroquinidine in vitro.
    Ludwig E, Schmid J, Beschke K, Ebner T.
    J Pharmacol Exp Ther; 1999 Jul 24; 290(1):1-8. PubMed ID: 10381752
    [Abstract] [Full Text] [Related]

  • 19. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S, Fujimaki Y, Yokoyama H, Okazaki O, Sudo K.
    Drug Metab Dispos; 2005 Nov 24; 33(11):1628-36. PubMed ID: 16049129
    [Abstract] [Full Text] [Related]

  • 20. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.
    Hamman MA, Thompson GA, Hall SD.
    Biochem Pharmacol; 1997 Jul 01; 54(1):33-41. PubMed ID: 9296349
    [Abstract] [Full Text] [Related]


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