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65 related items for PubMed ID: 9500859

  • 1. Intracellular compartmentalization of PDE4 cyclic AMP-specific phosphodiesterases.
    Scotland G, Beard M, Erdogan S, Huston E, McCallum F, MacKenzie SJ, Peden AH, Pooley L, Rena NG, Ross AH, Yarwood SJ, Houslay MD.
    Methods; 1998 Jan; 14(1):65-79. PubMed ID: 9500859
    [Abstract] [Full Text] [Related]

  • 2. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
    Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC.
    J Pharmacol Exp Ther; 2007 Aug; 322(2):600-9. PubMed ID: 17519386
    [Abstract] [Full Text] [Related]

  • 3. PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.
    Houslay MD, Adams DR.
    Biochem J; 2003 Feb 15; 370(Pt 1):1-18. PubMed ID: 12444918
    [Abstract] [Full Text] [Related]

  • 4. Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family.
    McPhee I, Pooley L, Lobban M, Bolger G, Houslay MD.
    Biochem J; 1995 Sep 15; 310 ( Pt 3)(Pt 3):965-74. PubMed ID: 7575434
    [Abstract] [Full Text] [Related]

  • 5. In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting.
    Beard MB, Huston E, Campbell L, Gall I, McPhee I, Yarwood S, Scotland G, Houslay MD.
    Cell Signal; 2002 May 15; 14(5):453-65. PubMed ID: 11882390
    [Abstract] [Full Text] [Related]

  • 6. Ndel1 alters its conformation by sequestering cAMP-specific phosphodiesterase-4D3 (PDE4D3) in a manner that is dynamically regulated through Protein Kinase A (PKA).
    Collins DM, Murdoch H, Dunlop AJ, Charych E, Baillie GS, Wang Q, Herberg FW, Brandon N, Prinz A, Houslay MD.
    Cell Signal; 2008 Dec 15; 20(12):2356-69. PubMed ID: 18845247
    [Abstract] [Full Text] [Related]

  • 7. Identification and characterization of novel mouse PDE4D isoforms: molecular cloning, subcellular distribution and detection of isoform-specific intracellular localization signals.
    Chandrasekaran A, Toh KY, Low SH, Tay SK, Brenner S, Goh DL.
    Cell Signal; 2008 Jan 15; 20(1):139-53. PubMed ID: 18006274
    [Abstract] [Full Text] [Related]

  • 8. In cardiac myocytes, cAMP elevation triggers the down-regulation of transcripts and promoter activity for cyclic AMP phosphodiesterase-4A10 (PDE4A10).
    McCahill A, Campbell L, McSorley T, Sood A, Lynch MJ, Li X, Yan C, Baillie GS, Houslay MD.
    Cell Signal; 2008 Nov 15; 20(11):2071-83. PubMed ID: 18721873
    [Abstract] [Full Text] [Related]

  • 9. Specific use of start codons and cellular localization of splice variants of human phosphodiesterase 9A gene.
    Rentero C, Puigdomènech P.
    BMC Mol Biol; 2006 Nov 08; 7():39. PubMed ID: 17090334
    [Abstract] [Full Text] [Related]

  • 10. The oligomerization state determines regulatory properties and inhibitor sensitivity of type 4 cAMP-specific phosphodiesterases.
    Richter W, Conti M.
    J Biol Chem; 2004 Jul 16; 279(29):30338-48. PubMed ID: 15131123
    [Abstract] [Full Text] [Related]

  • 11. Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells.
    Zhu B, Kelly J, Vemavarapu L, Thompson WJ, Strada SJ.
    Biochem Pharmacol; 2004 Aug 01; 68(3):479-91. PubMed ID: 15242814
    [Abstract] [Full Text] [Related]

  • 12. Transcriptional activation of phosphodiesterase 7B1 by dopamine D1 receptor stimulation through the cyclic AMP/cyclic AMP-dependent protein kinase/cyclic AMP-response element binding protein pathway in primary striatal neurons.
    Sasaki T, Kotera J, Omori K.
    J Neurochem; 2004 Apr 01; 89(2):474-83. PubMed ID: 15056290
    [Abstract] [Full Text] [Related]

  • 13. Defective RNA splicing resulting from a mutation in the cyclic guanosine monophosphate-phosphodiesterase beta-subunit gene.
    Piriev NI, Shih JM, Farber DB.
    Invest Ophthalmol Vis Sci; 1998 Mar 01; 39(3):463-70. PubMed ID: 9501854
    [Abstract] [Full Text] [Related]

  • 14. Expression and characterization of deletion recombinants of two cGMP-inhibited cyclic nucleotide phosphodiesterases (PDE-3).
    He R, Komas N, Ekholm D, Murata T, Taira M, Hockman S, Degerman E, Manganiello VC.
    Cell Biochem Biophys; 1998 Mar 01; 29(1-2):89-111. PubMed ID: 9631240
    [Abstract] [Full Text] [Related]

  • 15. Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: advances in the development of specific phosphodiesterase inhibitors.
    Castro A, Jerez MJ, Gil C, Martinez A.
    Med Res Rev; 2005 Mar 01; 25(2):229-44. PubMed ID: 15514991
    [Abstract] [Full Text] [Related]

  • 16. Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase.
    Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB.
    Biochem Biophys Res Commun; 1998 May 29; 246(3):570-7. PubMed ID: 9618252
    [Abstract] [Full Text] [Related]

  • 17. Conservation and expression of an alternative 3' exon of Runx2 encoding a novel proline-rich C-terminal domain.
    Terry A, Kilbey A, Vaillant F, Stewart M, Jenkins A, Cameron E, Neil JC.
    Gene; 2004 Jul 07; 336(1):115-25. PubMed ID: 15225881
    [Abstract] [Full Text] [Related]

  • 18. Expression of the cAMP-phosphodiesterase PDE4D isoforms and age-related changes in follicle-stimulating hormone-stimulated PDE4 activities in immature rat sertoli cells.
    Levallet G, Levallet J, Bouraïma-Lelong H, Bonnamy PJ.
    Biol Reprod; 2007 May 07; 76(5):794-803. PubMed ID: 17215491
    [Abstract] [Full Text] [Related]

  • 19. Real-time monitoring of phosphodiesterase inhibition in intact cells.
    Herget S, Lohse MJ, Nikolaev VO.
    Cell Signal; 2008 Aug 07; 20(8):1423-31. PubMed ID: 18467075
    [Abstract] [Full Text] [Related]

  • 20. Differential expression and regulation of the cAMP-selective phosphodiesterase type 4A splice variants in rat brain by chronic antidepressant administration.
    D'Sa C, Eisch AJ, Bolger GB, Duman RS.
    Eur J Neurosci; 2005 Sep 07; 22(6):1463-75. PubMed ID: 16190900
    [Abstract] [Full Text] [Related]

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