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290 related items for PubMed ID: 9519160

  • 1. Microscale titrimetric and spectrophotometric methods for determination of ionization constants and partition coefficients of new drug candidates.
    Morgan ME, Lui K, Anderson BD.
    J Pharm Sci; 1998 Feb; 87(2):238-45. PubMed ID: 9519160
    [Abstract] [Full Text] [Related]

  • 2. Multiwavelength spectrophotometric determination of acid dissociation constants: Part II. First derivative vs. target factor analysis.
    Tam KY, Takács-Novák K.
    Pharm Res; 1999 Mar; 16(3):374-81. PubMed ID: 10213367
    [Abstract] [Full Text] [Related]

  • 3. pH-metric log P. II: Refinement of partition coefficients and ionization constants of multiprotic substances.
    Avdeef A.
    J Pharm Sci; 1993 Feb; 82(2):183-90. PubMed ID: 8445533
    [Abstract] [Full Text] [Related]

  • 4. Spectrophotometric pKa determination of ionizable pharmaceuticals: Resolution of molecules with weak pH-dependent spectral shift.
    Dohoda D, Tsinman K, Tsinman O, Wang H, Tam KY.
    J Pharm Biomed Anal; 2015 Oct 10; 114():88-96. PubMed ID: 26026267
    [Abstract] [Full Text] [Related]

  • 5. Solubility, stability and ionization behaviour of famotidine.
    Islam MS, Narurkar MM.
    J Pharm Pharmacol; 1993 Aug 10; 45(8):682-6. PubMed ID: 7901363
    [Abstract] [Full Text] [Related]

  • 6. Determination of dissociation constants of some pharmaceutical compounds using derivative spectrophotometry.
    Hewala II, el-Yazbi FA, Awad A, Wahbi AM.
    J Clin Pharm Ther; 1992 Aug 10; 17(4):233-9. PubMed ID: 1429917
    [Abstract] [Full Text] [Related]

  • 7. Determination of protonation macro- and microconstants and octanol/water partition coefficient of the antiinflammatory drug niflumic acid.
    Takács-Novák K, Avdeef A, Box KJ, Podányi B, Szász G.
    J Pharm Biomed Anal; 1994 Nov 10; 12(11):1369-77. PubMed ID: 7849133
    [Abstract] [Full Text] [Related]

  • 8. Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts.
    Andrés A, Rosés M, Ràfols C, Bosch E, Espinosa S, Segarra V, Huerta JM.
    Eur J Pharm Sci; 2015 Aug 30; 76():181-91. PubMed ID: 25968358
    [Abstract] [Full Text] [Related]

  • 9. Fundamental properties of local anesthetics. I. The dependence of lidocaine's ionization and octanol:buffer partitioning on solvent and temperature.
    Sanchez V, Arthur GR, Strichartz GR.
    Anesth Analg; 1987 Feb 30; 66(2):159-65. PubMed ID: 3813059
    [Abstract] [Full Text] [Related]

  • 10. Electrochemical determination of partition coefficients of drugs.
    Kontturi K, Murtomäki L.
    J Pharm Sci; 1992 Oct 30; 81(10):970-5. PubMed ID: 1432622
    [Abstract] [Full Text] [Related]

  • 11. [Practical aspects of partition measurements according to GLP rules].
    Takácsné Novák K.
    Acta Pharm Hung; 1997 Sep 30; 67(5):179-91. PubMed ID: 9432865
    [Abstract] [Full Text] [Related]

  • 12. Ionization constants by curve fitting: determination of partition and distribution coefficients of acids and bases and their ions.
    Clarke FH, Cahoon NM.
    J Pharm Sci; 1987 Aug 30; 76(8):611-20. PubMed ID: 11002819
    [Abstract] [Full Text] [Related]

  • 13. Simple procedure for determining octanol--aqueous partition, distribution, and ionization coefficients by reversed-phase high-pressure liquid chromatography.
    Unger SH, Cook JR, Hollenberg JS.
    J Pharm Sci; 1978 Oct 30; 67(10):1364-7. PubMed ID: 702280
    [Abstract] [Full Text] [Related]

  • 14. Potentiometric and spectrophotometric pKa determination of water-insoluble compounds: validation study in a new cosolvent system.
    Völgyi G, Ruiz R, Box K, Comer J, Bosch E, Takács-Novák K.
    Anal Chim Acta; 2007 Feb 05; 583(2):418-28. PubMed ID: 17386575
    [Abstract] [Full Text] [Related]

  • 15. The potentiometric and spectrophotometric determination of dissociation constants for same 2-mercapto-5-R-amino-1,3,4-thiadiazole derivatives.
    Roman L, Mirel S, Florean E, Oprean R.
    J Pharm Biomed Anal; 1998 Oct 05; 18(1-2):137-44. PubMed ID: 9863951
    [Abstract] [Full Text] [Related]

  • 16. Accurate potentiometric determination of lipid membrane-water partition coefficients and apparent dissociation constants of ionizable drugs: electrostatic corrections.
    Elsayed MM, Vierl U, Cevc G.
    Pharm Res; 2009 Jun 05; 26(6):1332-43. PubMed ID: 19283456
    [Abstract] [Full Text] [Related]

  • 17. Novel medium-throughput technique for investigating drug-cyclodextrin complexation by pH-metric titration using the partition coefficient method.
    Dargó G, Boros K, Péter L, Malanga M, Sohajda T, Szente L, Balogh GT.
    Int J Pharm; 2018 May 05; 542(1-2):100-107. PubMed ID: 29530562
    [Abstract] [Full Text] [Related]

  • 18. Determination of ionization constant (pKa) and octanol-water partition coefficient (Log P) of cyclopiazonic acid.
    Sobolev VS.
    J AOAC Int; 2005 May 05; 88(5):1367-70. PubMed ID: 16385984
    [Abstract] [Full Text] [Related]

  • 19. Clofazimine pKa Determination by Potentiometry and Spectrophotometry: Reverse Cosolvent Dependence as an Indicator of the Presence of Dimers in Aqueous Solutions.
    Verbić TŽ, Tam KY, Veljković DŽ, Serajuddin ATM, Avdeef A.
    Mol Pharm; 2023 Jun 05; 20(6):3160-3169. PubMed ID: 37096898
    [Abstract] [Full Text] [Related]

  • 20. Reliability and uncertainty in the estimation of pKa by least squares nonlinear regression analysis of multiwavelength spectrophotometric pH titration data.
    Meloun M, Syrový T, Bordovská S, Vrána A.
    Anal Bioanal Chem; 2007 Feb 05; 387(3):941-55. PubMed ID: 17216158
    [Abstract] [Full Text] [Related]

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