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164 related items for PubMed ID: 9521084

  • 1. Co-capping studies reveal CD8/TCR interactions after capping CD8 beta polypeptides and intracellular associations of CD8 with p56(lck).
    Kwan Lim GE, McNeill L, Whitley K, Becker DL, Zamoyska R.
    Eur J Immunol; 1998 Feb; 28(2):745-54. PubMed ID: 9521084
    [Abstract] [Full Text] [Related]

  • 2. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 3. CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes.
    Arcaro A, Grégoire C, Bakker TR, Baldi L, Jordan M, Goffin L, Boucheron N, Wurm F, van der Merwe PA, Malissen B, Luescher IF.
    J Exp Med; 2001 Nov 19; 194(10):1485-95. PubMed ID: 11714755
    [Abstract] [Full Text] [Related]

  • 4. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
    Casas J, Brzostek J, Zarnitsyna VI, Hong JS, Wei Q, Hoerter JA, Fu G, Ampudia J, Zamoyska R, Zhu C, Gascoigne NR.
    Nat Commun; 2014 Nov 27; 5():5624. PubMed ID: 25427562
    [Abstract] [Full Text] [Related]

  • 5. Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction.
    Dornan S, Sebestyen Z, Gamble J, Nagy P, Bodnar A, Alldridge L, Doe S, Holmes N, Goff LK, Beverley P, Szollosi J, Alexander DR.
    J Biol Chem; 2002 Jan 18; 277(3):1912-8. PubMed ID: 11694532
    [Abstract] [Full Text] [Related]

  • 6. CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
    Artyomov MN, Lis M, Devadas S, Davis MM, Chakraborty AK.
    Proc Natl Acad Sci U S A; 2010 Sep 28; 107(39):16916-21. PubMed ID: 20837541
    [Abstract] [Full Text] [Related]

  • 7. Sequestration of CD4-associated Lck from the TCR complex may elicit T cell hyporesponsiveness in nonobese diabetic mice.
    Zhang J, Salojin K, Delovitch TL.
    J Immunol; 1998 Feb 01; 160(3):1148-57. PubMed ID: 9570528
    [Abstract] [Full Text] [Related]

  • 8. CD8 expression allows T cell signaling by monomeric peptide-MHC complexes.
    Delon J, Grégoire C, Malissen B, Darche S, Lemaître F, Kourilsky P, Abastado JP, Trautmann A.
    Immunity; 1998 Oct 01; 9(4):467-73. PubMed ID: 9806633
    [Abstract] [Full Text] [Related]

  • 9. Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
    Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, Schober K, Busch DH, Weiss A, Huppa JB, Stepanek O.
    Nat Immunol; 2023 Jan 01; 24(1):174-185. PubMed ID: 36564464
    [Abstract] [Full Text] [Related]

  • 10. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S, Baker M, Turner M, Holmes N, Alexander DR.
    Eur J Immunol; 1999 Aug 01; 29(8):2376-84. PubMed ID: 10458749
    [Abstract] [Full Text] [Related]

  • 11. Positive and negative selection of thymocytes depends on Lck interaction with the CD4 and CD8 coreceptors.
    Trobridge PA, Forbush KA, Levin SD.
    J Immunol; 2001 Jan 15; 166(2):809-18. PubMed ID: 11145654
    [Abstract] [Full Text] [Related]

  • 12. Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association.
    Chan IT, Limmer A, Louie MC, Bullock ED, Fung-Leung WP, Mak TW, Loh DY.
    Science; 1993 Sep 17; 261(5128):1581-4. PubMed ID: 8372352
    [Abstract] [Full Text] [Related]

  • 13. Interactions of CD45-associated protein with the antigen receptor signaling machinery in T-lymphocytes.
    Veillette A, Soussou D, Latour S, Davidson D, Gervais FG.
    J Biol Chem; 1999 May 14; 274(20):14392-9. PubMed ID: 10318863
    [Abstract] [Full Text] [Related]

  • 14. Evidence for differential intracellular signaling via CD4 and CD8 molecules.
    Ravichandran KS, Burakoff SJ.
    J Exp Med; 1994 Feb 01; 179(2):727-32. PubMed ID: 8294879
    [Abstract] [Full Text] [Related]

  • 15. A CD8/Lck transgene is able to drive thymocyte differentiation.
    Fragoso RC, Pyarajan S, Irie HY, Burakoff SJ.
    J Immunol; 2006 Nov 01; 177(9):6007-17. PubMed ID: 17056525
    [Abstract] [Full Text] [Related]

  • 16. Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling.
    Julius M, Maroun CR, Haughn L.
    Immunol Today; 1993 Apr 01; 14(4):177-83. PubMed ID: 8499078
    [Abstract] [Full Text] [Related]

  • 17. High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.
    Buslepp J, Kerry SE, Loftus D, Frelinger JA, Appella E, Collins EJ.
    J Immunol; 2003 Jan 01; 170(1):373-83. PubMed ID: 12496422
    [Abstract] [Full Text] [Related]

  • 18. Regulation of T cell development by c-Cbl: essential role of Lck.
    Chiang YJ, Hodes RJ.
    Int Immunol; 2015 May 01; 27(5):245-51. PubMed ID: 25477210
    [Abstract] [Full Text] [Related]

  • 19. TCR-induced T cell activation leads to simultaneous phosphorylation at Y505 and Y394 of p56(lck) residues.
    Nyakeriga AM, Garg H, Joshi A.
    Cytometry A; 2012 Sep 01; 81(9):797-805. PubMed ID: 22674786
    [Abstract] [Full Text] [Related]

  • 20. Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering.
    Viola A, Salio M, Tuosto L, Linkert S, Acuto O, Lanzavecchia A.
    J Exp Med; 1997 Nov 17; 186(10):1775-9. PubMed ID: 9362538
    [Abstract] [Full Text] [Related]


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