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422 related items for PubMed ID: 9521743

  • 1. Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands.
    Szegletes T, Mallender WD, Rosenberry TL.
    Biochemistry; 1998 Mar 24; 37(12):4206-16. PubMed ID: 9521743
    [Abstract] [Full Text] [Related]

  • 2. Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect.
    Szegletes T, Mallender WD, Thomas PJ, Rosenberry TL.
    Biochemistry; 1999 Jan 05; 38(1):122-33. PubMed ID: 9890890
    [Abstract] [Full Text] [Related]

  • 3. Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.
    Johnson JL, Cusack B, Davies MP, Fauq A, Rosenberry TL.
    Biochemistry; 2003 May 13; 42(18):5438-52. PubMed ID: 12731886
    [Abstract] [Full Text] [Related]

  • 4. Binding of the neurotoxin fasciculin 2 to the acetylcholinesterase peripheral site drastically reduces the association and dissociation rate constants for N-methylacridinium binding to the active site.
    Rosenberry TL, Rabl CR, Neumann E.
    Biochemistry; 1996 Jan 23; 35(3):685-90. PubMed ID: 8547248
    [Abstract] [Full Text] [Related]

  • 5. A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate.
    Rosenberry TL, Mallender WD, Thomas PJ, Szegletes T.
    Chem Biol Interact; 1999 May 14; 119-120():85-97. PubMed ID: 10421442
    [Abstract] [Full Text] [Related]

  • 6. Interactions between the peripheral site and the acylation site in acetylcholinesterase.
    Rosenberry TL, Johnson JL, Cusack B, Thomas JL, Emani S, Venkatasubban KS.
    Chem Biol Interact; 2005 Dec 15; 157-158():181-9. PubMed ID: 16256966
    [Abstract] [Full Text] [Related]

  • 7. Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity.
    Wong DM, Greenblatt HM, Dvir H, Carlier PR, Han YF, Pang YP, Silman I, Sussman JL.
    J Am Chem Soc; 2003 Jan 15; 125(2):363-73. PubMed ID: 12517147
    [Abstract] [Full Text] [Related]

  • 8. Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation.
    Eastman J, Wilson EJ, Cerveñansky C, Rosenberry TL.
    J Biol Chem; 1995 Aug 25; 270(34):19694-701. PubMed ID: 7649979
    [Abstract] [Full Text] [Related]

  • 9. Acetylthiocholine binds to asp74 at the peripheral site of human acetylcholinesterase as the first step in the catalytic pathway.
    Mallender WD, Szegletes T, Rosenberry TL.
    Biochemistry; 2000 Jul 04; 39(26):7753-63. PubMed ID: 10869180
    [Abstract] [Full Text] [Related]

  • 10. Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives.
    Radić Z, Reiner E, Taylor P.
    Mol Pharmacol; 1991 Jan 04; 39(1):98-104. PubMed ID: 1987454
    [Abstract] [Full Text] [Related]

  • 11. Interaction of tetrahydroaminoacridine with acetylcholinesterase and butyrylcholinesterase.
    Berman HA, Leonard K.
    Mol Pharmacol; 1992 Feb 04; 41(2):412-8. PubMed ID: 1538717
    [Abstract] [Full Text] [Related]

  • 12. Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites.
    De Ferrari GV, Mallender WD, Inestrosa NC, Rosenberry TL.
    J Biol Chem; 2001 Jun 29; 276(26):23282-7. PubMed ID: 11313335
    [Abstract] [Full Text] [Related]

  • 13. Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands. Distinct effects of propidium and fasciculin.
    Mallender WD, Szegletes T, Rosenberry TL.
    J Biol Chem; 1999 Mar 26; 274(13):8491-9. PubMed ID: 10085081
    [Abstract] [Full Text] [Related]

  • 14. Heterocyclic inhibitors of AChE acylation and peripheral sites.
    Bolognesi ML, Andrisano V, Bartolini M, Cavalli A, Minarini A, Recanatini M, Rosini M, Tumiatti V, Melchiorre C.
    Farmaco; 2005 Mar 26; 60(6-7):465-73. PubMed ID: 15878569
    [Abstract] [Full Text] [Related]

  • 15. Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase.
    Eichler J, Anselment A, Sussman JL, Massoulié J, Silman I.
    Mol Pharmacol; 1994 Feb 26; 45(2):335-40. PubMed ID: 8114681
    [Abstract] [Full Text] [Related]

  • 16. Allosteric control of acetylcholinesterase activity by monoclonal antibodies.
    Saxena A, Hur R, Doctor BP.
    Biochemistry; 1998 Jan 06; 37(1):145-54. PubMed ID: 9425034
    [Abstract] [Full Text] [Related]

  • 17. [The fasciculin-acetylcholinesterase interaction].
    Marchot P.
    J Soc Biol; 1999 Jan 06; 193(6):505-8. PubMed ID: 10783708
    [Abstract] [Full Text] [Related]

  • 18. Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase.
    Auletta JT, Johnson JL, Rosenberry TL.
    Chem Biol Interact; 2010 Sep 06; 187(1-3):135-41. PubMed ID: 20493829
    [Abstract] [Full Text] [Related]

  • 19. Conformers of acetylcholinesterase: a mechanism of allosteric control.
    Taylor JL, Mayer RT, Himel CM.
    Mol Pharmacol; 1994 Jan 06; 45(1):74-83. PubMed ID: 8302283
    [Abstract] [Full Text] [Related]

  • 20. Kinetic model of ethopropazine interaction with horse serum butyrylcholinesterase and its docking into the active site.
    Golicnik M, Sinko G, Simeon-Rudolf V, Grubic Z, Stojan J.
    Arch Biochem Biophys; 2002 Feb 01; 398(1):23-31. PubMed ID: 11811945
    [Abstract] [Full Text] [Related]

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