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Journal Abstract Search

264 related items for PubMed ID: 9531515

  • 1. Development of a non-high pressure liquid chromatography assay to determine testosterone hydroxylase (CYP3A) activity in human liver microsomes.
    Draper AJ, Madan A, Smith K, Parkinson A.
    Drug Metab Dispos; 1998 Apr; 26(4):299-304. PubMed ID: 9531515
    [Abstract] [Full Text] [Related]

  • 2. Development of a non-high pressure liquid chromatography assay to determine [14C]chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes.
    Draper AJ, Madan A, Latham J, Parkinson A.
    Drug Metab Dispos; 1998 Apr; 26(4):305-12. PubMed ID: 9531516
    [Abstract] [Full Text] [Related]

  • 3. Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Mäenpää J, Hall SD, Ring BJ, Strom SC, Wrighton SA.
    Pharmacogenetics; 1998 Apr; 8(2):137-55. PubMed ID: 10022752
    [Abstract] [Full Text] [Related]

  • 4. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

  • 5. Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe.
    Chauret N, Tremblay N, Lackman RL, Gauthier JY, Silva JM, Marois J, Yergey JA, Nicoll-Griffith DA.
    Anal Biochem; 1999 Dec 15; 276(2):215-26. PubMed ID: 10603245
    [Abstract] [Full Text] [Related]

  • 6. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep 15; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 7. Thin-layer chromatographic analysis of human CYP3A-catalyzed testosterone 6 beta-hydroxylation.
    Waxman DJ, Chang TK.
    Methods Mol Biol; 1998 Sep 15; 107():153-61. PubMed ID: 14577225
    [No Abstract] [Full Text] [Related]

  • 8. Metabolism of phencyclidine by human liver microsomes.
    Laurenzana EM, Owens SM.
    Drug Metab Dispos; 1997 May 15; 25(5):557-63. PubMed ID: 9152594
    [Abstract] [Full Text] [Related]

  • 9. Stereoselective metabolism of cisapride and enantiomer-enantiomer interaction in human cytochrome P450 enzymes: major role of CYP3A.
    Desta Z, Soukhova N, Morocho AM, Flockhart DA.
    J Pharmacol Exp Ther; 2001 Aug 15; 298(2):508-20. PubMed ID: 11454912
    [Abstract] [Full Text] [Related]

  • 10. Thin-layer chromatography analysis of human CYP3A-catalyzed testosterone 6beta-hydroxylation.
    Waxman DJ, Chang TK.
    Methods Mol Biol; 2006 Aug 15; 320():133-41. PubMed ID: 16719384
    [Abstract] [Full Text] [Related]

  • 11. Antitumor activity of methoxymorpholinyl doxorubicin: potentiation by cytochrome P450 3A metabolism.
    Lu H, Waxman DJ.
    Mol Pharmacol; 2005 Jan 15; 67(1):212-9. PubMed ID: 15465924
    [Abstract] [Full Text] [Related]

  • 12. Microsomal metabolism of delavirdine: evidence for mechanism-based inactivation of human cytochrome P450 3A.
    Voorman RL, Maio SM, Payne NA, Zhao Z, Koeplinger KA, Wang X.
    J Pharmacol Exp Ther; 1998 Oct 15; 287(1):381-8. PubMed ID: 9765359
    [Abstract] [Full Text] [Related]

  • 13. Drug interactions with calcium channel blockers: possible involvement of metabolite-intermediate complexation with CYP3A.
    Ma B, Prueksaritanont T, Lin JH.
    Drug Metab Dispos; 2000 Feb 15; 28(2):125-30. PubMed ID: 10640508
    [Abstract] [Full Text] [Related]

  • 14. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.
    Pearce RE, Gotschall RR, Kearns GL, Leeder JS.
    Drug Metab Dispos; 2001 Dec 15; 29(12):1548-54. PubMed ID: 11717173
    [Abstract] [Full Text] [Related]

  • 15. Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells.
    Parola M, Robino G, Bordone R, Leonarduzzi G, Casini A, Pinzani M, Neve E, Bellomo G, Dianzani MU, Ingelman-Sundberg M, Albano E.
    Biochem Biophys Res Commun; 1997 Sep 18; 238(2):420-4. PubMed ID: 9299524
    [Abstract] [Full Text] [Related]

  • 16. Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4.
    Komatsu T, Yamazaki H, Asahi S, Gillam EM, Guengerich FP, Nakajima M, Yokoi T.
    Drug Metab Dispos; 2000 Nov 18; 28(11):1361-8. PubMed ID: 11038165
    [Abstract] [Full Text] [Related]

  • 17. In vitro and in vivo effects of the arylamine human immunodeficiency virus protease inhibitor 4R-(4alpha,5alpha,6beta, 7beta)-1-[(3-(1-imidazoylcarbamoyl)phenyl)methyl]-3-[(3-aminophenyl)m ethyl]hexahydro-5,6-dihydroxy-4,7-bis(phenylmethyl)-2H-1, 3-diazepin-2-one (SD894) on rat hepatic cytochrome P450 2B and 3A.
    Grubb MF, Diamond S, Christ DD.
    Drug Metab Dispos; 1997 Dec 18; 25(12):1424-8. PubMed ID: 9394033
    [Abstract] [Full Text] [Related]

  • 18. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation.
    Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD.
    J Pharmacol Exp Ther; 1999 Sep 18; 290(3):1116-25. PubMed ID: 10454485
    [Abstract] [Full Text] [Related]

  • 19. Ring hydroxylation of [o-3H]methoxychlor as a probe for liver microsomal CYP2B activity: potential for in vivo CYP2B assay.
    Stresser DM, Dehal SS, Kupfer D.
    Anal Biochem; 1996 Jan 01; 233(1):100-7. PubMed ID: 8789153
    [Abstract] [Full Text] [Related]

  • 20. Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Xenobiotica; 2001 Oct 01; 31(10):713-23. PubMed ID: 11695850
    [Abstract] [Full Text] [Related]

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