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90 related items for PubMed ID: 9535737

  • 1. The presenilin 1 mutation (M146V) linked to familial Alzheimer's disease attenuates the neuronal differentiation of NTera 2 cells.
    Tokuhiro S, Tomita T, Iwata H, Kosaka T, Saido TC, Maruyama K, Iwatsubo T.
    Biochem Biophys Res Commun; 1998 Mar 27; 244(3):751-5. PubMed ID: 9535737
    [Abstract] [Full Text] [Related]

  • 2. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA.
    Exp Neurol; 2004 Aug 27; 188(2):224-37. PubMed ID: 15246822
    [Abstract] [Full Text] [Related]

  • 3. Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein.
    Hamano T, Mutoh T, Tabira T, Araki W, Kuriyama M, Mihara T, Yano S, Yamamoto H.
    Brain Res Mol Brain Res; 2005 Jun 13; 137(1-2):70-6. PubMed ID: 15950763
    [Abstract] [Full Text] [Related]

  • 4. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 5. Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
    Malik B, Currais A, Soriano S.
    J Neurochem; 2008 Jul 15; 106(2):912-6. PubMed ID: 18466334
    [Abstract] [Full Text] [Related]

  • 6. Functional phenotype in transgenic mice expressing mutant human presenilin-1.
    Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K.
    Neurobiol Dis; 2000 Apr 15; 7(2):119-26. PubMed ID: 10783295
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of AMPA responses by mutated presenilin 1.
    Moerman AM, Barger SW.
    J Neurosci Res; 1999 Sep 15; 57(6):962-7. PubMed ID: 10467268
    [Abstract] [Full Text] [Related]

  • 8. Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.
    Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ.
    Neurobiol Dis; 1998 Aug 15; 5(2):107-16. PubMed ID: 9746908
    [Abstract] [Full Text] [Related]

  • 9. Presenilin 1 mediates retinoic acid-induced differentiation of SH-SY5Y cells through facilitation of Wnt signaling.
    Uemura K, Kitagawa N, Kohno R, Kuzuya A, Kageyama T, Shibasaki H, Shimohama S.
    J Neurosci Res; 2003 Jul 15; 73(2):166-75. PubMed ID: 12836159
    [Abstract] [Full Text] [Related]

  • 10. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
    Shimojo M, Sahara N, Murayama M, Ichinose H, Takashima A.
    Neurosci Res; 2007 Mar 15; 57(3):446-53. PubMed ID: 17210196
    [Abstract] [Full Text] [Related]

  • 11. Presenilin 1 is involved in maturation and trafficking of N-cadherin to the plasma membrane.
    Uemura K, Kitagawa N, Kohno R, Kuzuya A, Kageyama T, Chonabayashi K, Shibasaki H, Shimohama S.
    J Neurosci Res; 2003 Oct 15; 74(2):184-91. PubMed ID: 14515347
    [Abstract] [Full Text] [Related]

  • 12. Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.
    Eckert A, Schindowski K, Leutner S, Luckhaus C, Touchet N, Czech C, Müller WE.
    Neurobiol Dis; 2001 Apr 15; 8(2):331-42. PubMed ID: 11300728
    [Abstract] [Full Text] [Related]

  • 13. Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.
    Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M.
    Ann Neurol; 1998 Feb 15; 43(2):256-8. PubMed ID: 9485068
    [Abstract] [Full Text] [Related]

  • 14. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 15; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 15. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.
    Parent A, Linden DJ, Sisodia SS, Borchelt DR.
    Neurobiol Dis; 1999 Feb 15; 6(1):56-62. PubMed ID: 10078973
    [Abstract] [Full Text] [Related]

  • 16. Presenilin is required for proper morphology and function of neurons in C. elegans.
    Wittenburg N, Eimer S, Lakowski B, Röhrig S, Rudolph C, Baumeister R.
    Nature; 2000 Jul 20; 406(6793):306-9. PubMed ID: 10917532
    [Abstract] [Full Text] [Related]

  • 17. Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.
    Culvenor JG, Evin G, Cooney MA, Wardan H, Sharples RA, Maher F, Reed G, Diehlmann A, Weidemann A, Beyreuther K, Masters CL.
    Exp Cell Res; 2000 Mar 15; 255(2):192-206. PubMed ID: 10694435
    [Abstract] [Full Text] [Related]

  • 18. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells.
    Verdile G, Groth D, Mathews PM, St George-Hyslop P, Fraser PE, Ramabhadran TV, Kwok JB, Schofield PR, Carter T, Gandy S, Martins RN.
    Mol Psychiatry; 2004 Jun 15; 9(6):594-602. PubMed ID: 14993906
    [Abstract] [Full Text] [Related]

  • 19. The presenilin 1 C92S mutation increases abeta 42 production.
    Lewis PA, Perez-Tur J, Golde TE, Hardy J.
    Biochem Biophys Res Commun; 2000 Oct 14; 277(1):261-3. PubMed ID: 11027672
    [Abstract] [Full Text] [Related]

  • 20. Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
    Hashimoto Y, Tsukamoto E, Niikura T, Yamagishi Y, Ishizaka M, Aiso S, Takashima A, Nishimoto I.
    J Neurosci Res; 2004 Feb 01; 75(3):417-28. PubMed ID: 14743455
    [Abstract] [Full Text] [Related]

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