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Journal Abstract Search

347 related items for PubMed ID: 9536080

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  • 3. Mutant huntingtin forms in vivo complexes with distinct context-dependent conformations of the polyglutamine segment.
    Persichetti F, Trettel F, Huang CC, Fraefel C, Timmers HT, Gusella JF, MacDonald ME.
    Neurobiol Dis; 1999 Oct; 6(5):364-75. PubMed ID: 10527804
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  • 4. Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
    Huang CC, Faber PW, Persichetti F, Mittal V, Vonsattel JP, MacDonald ME, Gusella JF.
    Somat Cell Mol Genet; 1998 Jul; 24(4):217-33. PubMed ID: 10410676
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  • 5. A cellular model that recapitulates major pathogenic steps of Huntington's disease.
    Lunkes A, Mandel JL.
    Hum Mol Genet; 1998 Sep; 7(9):1355-61. PubMed ID: 9700187
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  • 6. Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
    Hazeki N, Nakamura K, Goto J, Kanazawa I.
    Biochem Biophys Res Commun; 1999 Mar 16; 256(2):361-6. PubMed ID: 10079189
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  • 7. Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.
    Chun W, Lesort M, Tucholski J, Faber PW, MacDonald ME, Ross CA, Johnson GV.
    Neurobiol Dis; 2001 Jun 16; 8(3):391-404. PubMed ID: 11442349
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  • 8. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
    Ho LW, Brown R, Maxwell M, Wyttenbach A, Rubinsztein DC.
    J Med Genet; 2001 Jul 16; 38(7):450-2. PubMed ID: 11432963
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  • 9. Polyglutamine pathogenesis.
    Ross CA, Wood JD, Schilling G, Peters MF, Nucifora FC, Cooper JK, Sharp AH, Margolis RL, Borchelt DR.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1005-11. PubMed ID: 10434299
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  • 10. Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release.
    Jana NR, Zemskov EA, Wang Gh, Nukina N.
    Hum Mol Genet; 2001 May 01; 10(10):1049-59. PubMed ID: 11331615
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  • 11. Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity.
    Li H, Li SH, Johnston H, Shelbourne PF, Li XJ.
    Nat Genet; 2000 Aug 01; 25(4):385-9. PubMed ID: 10932179
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  • 12. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
    Yu ZX, Li SH, Evans J, Pillarisetti A, Li H, Li XJ.
    J Neurosci; 2003 Mar 15; 23(6):2193-202. PubMed ID: 12657678
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  • 13. In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease.
    Hackam AS, Singaraja R, Zhang T, Gan L, Hayden MR.
    Hum Mol Genet; 1999 Jan 15; 8(1):25-33. PubMed ID: 9887328
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  • 14. Polyglutamine repeat length-dependent proteolysis of huntingtin.
    Sun B, Fan W, Balciunas A, Cooper JK, Bitan G, Steavenson S, Denis PE, Young Y, Adler B, Daugherty L, Manoukian R, Elliott G, Shen W, Talvenheimo J, Teplow DB, Haniu M, Haldankar R, Wypych J, Ross CA, Citron M, Richards WG.
    Neurobiol Dis; 2002 Oct 15; 11(1):111-22. PubMed ID: 12460551
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  • 15. DMSO and glycerol reduce bacterial death induced by expression of truncated N-terminal huntingtin with expanded polyglutamine tracts.
    Nagao Y, Ishiguro H, Nukina N.
    Biochim Biophys Acta; 2000 Oct 18; 1502(2):247-56. PubMed ID: 11040449
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  • 16. Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
    Schilling G, Becher MW, Sharp AH, Jinnah HA, Duan K, Kotzuk JA, Slunt HH, Ratovitski T, Cooper JK, Jenkins NA, Copeland NG, Price DL, Ross CA, Borchelt DR.
    Hum Mol Genet; 1999 Mar 18; 8(3):397-407. PubMed ID: 9949199
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  • 17. Arfaptin 2 regulates the aggregation of mutant huntingtin protein.
    Peters PJ, Ning K, Palacios F, Boshans RL, Kazantsev A, Thompson LM, Woodman B, Bates GP, D'Souza-Schorey C.
    Nat Cell Biol; 2002 Mar 18; 4(3):240-5. PubMed ID: 11854752
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  • 18. SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.
    Sittler A, Wälter S, Wedemeyer N, Hasenbank R, Scherzinger E, Eickhoff H, Bates GP, Lehrach H, Wanker EE.
    Mol Cell; 1998 Oct 18; 2(4):427-36. PubMed ID: 9809064
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  • 19. Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis.
    Sugars KL, Brown R, Cook LJ, Swartz J, Rubinsztein DC.
    J Biol Chem; 2004 Feb 06; 279(6):4988-99. PubMed ID: 14627700
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  • 20. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.
    Goswami A, Dikshit P, Mishra A, Mulherkar S, Nukina N, Jana NR.
    Biochem Biophys Res Commun; 2006 Mar 31; 342(1):184-90. PubMed ID: 16472774
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