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PUBMED FOR HANDHELDS

Journal Abstract Search


238 related items for PubMed ID: 9538020

  • 1. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state.
    Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, Pastan I.
    Biochemistry; 1998 Apr 07; 37(14):5010-9. PubMed ID: 9538020
    [Abstract] [Full Text] [Related]

  • 2. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N, Moitra K, Silver C, Ghosh P, Chattopadhyay A, Dey S.
    Biochemistry; 2006 Feb 28; 45(8):2739-51. PubMed ID: 16489767
    [Abstract] [Full Text] [Related]

  • 3. Drug binding and nucleotide hydrolyzability are essential requirements in the vanadate-induced inhibition of the human P-glycoprotein ATPase.
    Rao US.
    Biochemistry; 1998 Oct 20; 37(42):14981-8. PubMed ID: 9778376
    [Abstract] [Full Text] [Related]

  • 4. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
    Tombline G, Donnelly DJ, Holt JJ, You Y, Ye M, Gannon MK, Nygren CL, Detty MR.
    Biochemistry; 2006 Jul 04; 45(26):8034-47. PubMed ID: 16800628
    [Abstract] [Full Text] [Related]

  • 5. Stoichiometry and affinity of nucleotide binding to P-glycoprotein during the catalytic cycle.
    Qu Q, Russell PL, Sharom FJ.
    Biochemistry; 2003 Feb 04; 42(4):1170-7. PubMed ID: 12549939
    [Abstract] [Full Text] [Related]

  • 6. Catalytic mechanism of P-glycoprotein.
    Senior AE.
    Acta Physiol Scand Suppl; 1998 Aug 04; 643():213-8. PubMed ID: 9789563
    [Abstract] [Full Text] [Related]

  • 7. Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport.
    Hrycyna CA, Airan LE, Germann UA, Ambudkar SV, Pastan I, Gottesman MM.
    Biochemistry; 1998 Sep 29; 37(39):13660-73. PubMed ID: 9753453
    [Abstract] [Full Text] [Related]

  • 8. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.
    Liu R, Sharom FJ.
    Biochemistry; 1996 Sep 10; 35(36):11865-73. PubMed ID: 8794769
    [Abstract] [Full Text] [Related]

  • 9. Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells.
    Wan CK, Zhu GY, Shen XL, Chattopadhyay A, Dey S, Fong WF.
    Biochem Pharmacol; 2006 Sep 28; 72(7):824-37. PubMed ID: 16889754
    [Abstract] [Full Text] [Related]

  • 10. Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis.
    Sauna ZE, Smith MM, Muller M, Ambudkar SV.
    J Biol Chem; 2001 Jun 15; 276(24):21199-208. PubMed ID: 11287418
    [Abstract] [Full Text] [Related]

  • 11. ATP occlusion by P-glycoprotein as a surrogate measure for drug coupling.
    Tombline G, Holt JJ, Gannon MK, Donnelly DJ, Wetzel B, Sawada GA, Raub TJ, Detty MR.
    Biochemistry; 2008 Mar 11; 47(10):3294-307. PubMed ID: 18275155
    [Abstract] [Full Text] [Related]

  • 12. Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates.
    Kerr KM, Sauna ZE, Ambudkar SV.
    J Biol Chem; 2001 Mar 23; 276(12):8657-64. PubMed ID: 11121420
    [Abstract] [Full Text] [Related]

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  • 15. P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.
    Senior AE, Bhagat S.
    Biochemistry; 1998 Jan 20; 37(3):831-6. PubMed ID: 9454572
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  • 19. Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1).
    Maki N, Dey S.
    Biochem Pharmacol; 2006 Jul 14; 72(2):145-55. PubMed ID: 16729976
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