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358 related items for PubMed ID: 9546425

  • 1. Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
    Denissenko MF, Pao A, Pfeifer GP, Tang M.
    Oncogene; 1998 Mar 12; 16(10):1241-7. PubMed ID: 9546425
    [Abstract] [Full Text] [Related]

  • 2. Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.
    Hu W, Feng Z, Tang MS.
    Biochemistry; 2003 Aug 26; 42(33):10012-23. PubMed ID: 12924950
    [Abstract] [Full Text] [Related]

  • 3. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH, Smith LE, Feng Z, Tang M, Lee CS, Pfeifer GP.
    Cancer Res; 2001 Oct 01; 61(19):7110-7. PubMed ID: 11585742
    [Abstract] [Full Text] [Related]

  • 4. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA, Zhu Q, El-Mahdy M, Venkatachalam S, Wani AA.
    Cancer Res; 2000 Apr 15; 60(8):2273-80. PubMed ID: 10786695
    [Abstract] [Full Text] [Related]

  • 5. Use of UvrABC nuclease to quantify benzo[a]pyrene diol epoxide-DNA adduct formation at methylated versus unmethylated CpG sites in the p53 gene.
    Tang MS, Zheng JB, Denissenko MF, Pfeifer GP, Zheng Y.
    Carcinogenesis; 1999 Jun 15; 20(6):1085-9. PubMed ID: 10357792
    [Abstract] [Full Text] [Related]

  • 6. Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
    Matter B, Wang G, Jones R, Tretyakova N.
    Chem Res Toxicol; 2004 Jun 15; 17(6):731-41. PubMed ID: 15206894
    [Abstract] [Full Text] [Related]

  • 7. Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer.
    Feng Z, Hu W, Chen JX, Pao A, Li H, Rom W, Hung MC, Tang MS.
    J Natl Cancer Inst; 2002 Oct 16; 94(20):1527-36. PubMed ID: 12381705
    [Abstract] [Full Text] [Related]

  • 8. Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.
    Tretyakova N, Matter B, Jones R, Shallop A.
    Biochemistry; 2002 Jul 30; 41(30):9535-44. PubMed ID: 12135376
    [Abstract] [Full Text] [Related]

  • 9. Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra.
    Wei D, Maher VM, McCormick JJ.
    Proc Natl Acad Sci U S A; 1995 Mar 14; 92(6):2204-8. PubMed ID: 7892248
    [Abstract] [Full Text] [Related]

  • 10. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H, Bonala RR, Suzuki N, Johnson F, Grollman AP, Shibutani S.
    Biochemistry; 2004 Dec 21; 43(50):15922-8. PubMed ID: 15595848
    [Abstract] [Full Text] [Related]

  • 11. An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygium.
    Lai TJ, Tsai YY, Cheng YW, Chiang CC, Lee H, Chou MC, Chang JH.
    Mol Vis; 2006 Dec 24; 12():1687-91. PubMed ID: 17213797
    [Abstract] [Full Text] [Related]

  • 12. Lack of a cell cycle-dependent strand bias for mutations induced in the HPRT gene by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in excision repair-deficient human cells.
    Chen RH, Maher VM, McCormick JJ.
    Cancer Res; 1991 May 15; 51(10):2587-92. PubMed ID: 1902394
    [Abstract] [Full Text] [Related]

  • 13. High resolution mapping of UV-induced photoproducts in the Escherichia coli lacI gene. Inefficient repair of the non-transcribed strand correlates with high mutation frequency.
    Chandrasekhar D, Van Houten B.
    J Mol Biol; 1994 May 06; 238(3):319-32. PubMed ID: 8176728
    [Abstract] [Full Text] [Related]

  • 14. The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts.
    Denissenko MF, Koudriakova TB, Smith L, O'Connor TR, Riggs AD, Pfeifer GP.
    Oncogene; 1998 Dec 10; 17(23):3007-14. PubMed ID: 9881702
    [Abstract] [Full Text] [Related]

  • 15. Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide.
    Snyderwine EG, Bohr VA.
    Cancer Res; 1992 Aug 01; 52(15):4183-9. PubMed ID: 1638532
    [Abstract] [Full Text] [Related]

  • 16. Preferential DNA damage in the p53 gene by benzo[a]pyrene metabolites in cytochrome P4501A1-expressing xeroderma pigmentosum group A cells.
    Quan T, States JC.
    Mol Carcinog; 1996 May 01; 16(1):32-43. PubMed ID: 8634092
    [Abstract] [Full Text] [Related]

  • 17. Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.
    Chen RH, Maher VM, Brouwer J, van de Putte P, McCormick JJ.
    Proc Natl Acad Sci U S A; 1992 Jun 15; 89(12):5413-7. PubMed ID: 1608950
    [Abstract] [Full Text] [Related]

  • 18. Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.
    Dreij K, Seidel A, Jernström B.
    Chem Res Toxicol; 2005 Apr 15; 18(4):655-64. PubMed ID: 15833025
    [Abstract] [Full Text] [Related]

  • 19. High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Rojas M, Marie B, Vignaud JM, Martinet N, Siat J, Grosdidier G, Cascorbi I, Alexandrov K.
    Cancer Lett; 2004 Apr 30; 207(2):157-63. PubMed ID: 15072824
    [Abstract] [Full Text] [Related]

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