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Journal Abstract Search

201 related items for PubMed ID: 9548795

  • 1. Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.
    He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF.
    Chem Res Toxicol; 1998 Apr; 11(4):252-9. PubMed ID: 9548795
    [Abstract] [Full Text] [Related]

  • 2. The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2005 Apr; 313(1):154-64. PubMed ID: 15608076
    [Abstract] [Full Text] [Related]

  • 3. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K, Woolf TF, Hollenberg PF.
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
    [Abstract] [Full Text] [Related]

  • 4. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP.
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [Abstract] [Full Text] [Related]

  • 5. Distribution of furanocoumarins in grapefruit juice fractions.
    Manthey JA, Buslig BS.
    J Agric Food Chem; 2005 Jun 29; 53(13):5158-63. PubMed ID: 15969491
    [Abstract] [Full Text] [Related]

  • 6. Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes.
    Shimada T, Mernaugh RL, Guengerich FP.
    Arch Biochem Biophys; 2005 Mar 01; 435(1):207-16. PubMed ID: 15680923
    [Abstract] [Full Text] [Related]

  • 7. Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.
    Labroo RB, Paine MF, Thummel KE, Kharasch ED.
    Drug Metab Dispos; 1997 Sep 01; 25(9):1072-80. PubMed ID: 9311623
    [Abstract] [Full Text] [Related]

  • 8. Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
    Alvarez-Diez TM, Zheng J.
    Chem Res Toxicol; 2004 Feb 01; 17(2):150-7. PubMed ID: 14967002
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of in-vitro simvastatin metabolism in rat liver microsomes by bergamottin, a component of grapefruit juice.
    Le Goff-Klein N, Klein L, Hérin M, Koffel JC, Ubeaud G.
    J Pharm Pharmacol; 2004 Aug 01; 56(8):1007-14. PubMed ID: 15285845
    [Abstract] [Full Text] [Related]

  • 10. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.
    Chem Res Toxicol; 1999 Feb 01; 12(2):192-9. PubMed ID: 10027798
    [Abstract] [Full Text] [Related]

  • 11. The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone.
    Moody DE, Alburges ME, Parker RJ, Collins JM, Strong JM.
    Drug Metab Dispos; 1997 Dec 01; 25(12):1347-53. PubMed ID: 9394023
    [Abstract] [Full Text] [Related]

  • 12. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
    Yamazaki H, Shaw PM, Guengerich FP, Shimada T.
    Chem Res Toxicol; 1998 Jun 01; 11(6):659-65. PubMed ID: 9625734
    [Abstract] [Full Text] [Related]

  • 13. Inactivation of cytochrome P450 2E1 by tert-butylisothiocyanate.
    Kent UM, Roberts ES, Chun J, Hodge K, Juncaj J, Hollenberg PF.
    Chem Res Toxicol; 1998 Oct 01; 11(10):1154-61. PubMed ID: 9778311
    [Abstract] [Full Text] [Related]

  • 14. Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms.
    Perret A, Pompon D.
    Biochemistry; 1998 Aug 18; 37(33):11412-24. PubMed ID: 9708976
    [Abstract] [Full Text] [Related]

  • 15. [Grapefruit juice and drugs: a hazardous combination?].
    Lohezic-Le Devehat F, Marigny K, Doucet M, Javaudin L.
    Therapie; 2002 Aug 18; 57(5):432-45. PubMed ID: 12611197
    [Abstract] [Full Text] [Related]

  • 16. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases.
    Sridar C, Goosen TC, Kent UM, Williams JA, Hollenberg PF.
    Drug Metab Dispos; 2004 Jun 18; 32(6):587-94. PubMed ID: 15155549
    [Abstract] [Full Text] [Related]

  • 17. Identification of the human liver microsomal cytochrome P450s involved in the metabolism of N-nitrosodi-n-propylamine.
    Teiber JF, Hollenberg PF.
    Carcinogenesis; 2000 Aug 18; 21(8):1559-66. PubMed ID: 10910959
    [Abstract] [Full Text] [Related]

  • 18. Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Apr 18; 301(1):160-7. PubMed ID: 11907170
    [Abstract] [Full Text] [Related]

  • 19. Inhibition selectivity of grapefruit juice components on human cytochromes P450.
    Tassaneeyakul W, Guo LQ, Fukuda K, Ohta T, Yamazoe Y.
    Arch Biochem Biophys; 2000 Jun 15; 378(2):356-63. PubMed ID: 10860553
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of the selectivity of In vitro probes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.
    Hickman D, Wang JP, Wang Y, Unadkat JD.
    Drug Metab Dispos; 1998 Mar 15; 26(3):207-15. PubMed ID: 9492382
    [Abstract] [Full Text] [Related]

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