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Journal Abstract Search

144 related items for PubMed ID: 9548820

  • 1. Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells.
    Taatjes DJ, Fenick DJ, Koch TH.
    J Med Chem; 1998 Apr 09; 41(8):1306-14. PubMed ID: 9548820
    [Abstract] [Full Text] [Related]

  • 2. Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells.
    Fenick DJ, Taatjes DJ, Koch TH.
    J Med Chem; 1997 Aug 01; 40(16):2452-61. PubMed ID: 9258351
    [Abstract] [Full Text] [Related]

  • 3. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
    Taatjes DJ, Fenick DJ, Koch TH.
    Chem Res Toxicol; 1999 Jul 01; 12(7):588-96. PubMed ID: 10409398
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
    Podell ER, Harrington DJ, Taatjes DJ, Koch TH.
    Acta Crystallogr D Biol Crystallogr; 1999 Sep 01; 55(Pt 9):1516-23. PubMed ID: 10489446
    [Abstract] [Full Text] [Related]

  • 5. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.
    Taatjes DJ, Koch TH.
    Anticancer Res; 1999 Sep 01; 19(2A):1201-8. PubMed ID: 10368676
    [Abstract] [Full Text] [Related]

  • 6. Nuclear targeting and retention of anthracycline antitumor drugs in sensitive and resistant tumor cells.
    Taatjes DJ, Koch TH.
    Curr Med Chem; 2001 Jan 01; 8(1):15-29. PubMed ID: 11172689
    [Abstract] [Full Text] [Related]

  • 7. Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin.
    Taatjes DJ, Gaudiano G, Resing K, Koch TH.
    J Med Chem; 1997 Apr 11; 40(8):1276-86. PubMed ID: 9111302
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of the epidoxorubicin--formaldehyde conjugate, epidoxoform, in a mouse mammary carcinoma model.
    Dernell WS, Powers BE, Taatjes DJ, Cogan P, Gaudiano G, Koch TH.
    Cancer Invest; 2002 Apr 11; 20(5-6):713-24. PubMed ID: 12197227
    [Abstract] [Full Text] [Related]

  • 9. Structure-based design of a new bisintercalating anthracycline antibiotic.
    Chaires JB, Leng F, Przewloka T, Fokt I, Ling YH, Perez-Soler R, Priebe W.
    J Med Chem; 1997 Jan 31; 40(3):261-6. PubMed ID: 9022792
    [Abstract] [Full Text] [Related]

  • 10. Doxazolidine, a proposed active metabolite of doxorubicin that cross-links DNA.
    Post GC, Barthel BL, Burkhart DJ, Hagadorn JR, Koch TH.
    J Med Chem; 2005 Dec 01; 48(24):7648-57. PubMed ID: 16302805
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.
    Burke PJ, Koch TH.
    J Med Chem; 2004 Feb 26; 47(5):1193-206. PubMed ID: 14971899
    [Abstract] [Full Text] [Related]

  • 12. Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron.
    Taatjes DJ, Gaudiano G, Koch TH.
    Chem Res Toxicol; 1997 Sep 26; 10(9):953-61. PubMed ID: 9305576
    [Abstract] [Full Text] [Related]

  • 13. Structural requirements for the formation of anthracycline-DNA adducts.
    Cutts SM, Parker BS, Swift LP, Kimura KI, Phillips DR.
    Anticancer Drug Des; 2000 Oct 26; 15(5):373-86. PubMed ID: 11354313
    [Abstract] [Full Text] [Related]

  • 14. Doxorubicin-formaldehyde conjugate, doxoform: induction of apoptosis relative to doxorubicin.
    Burke PJ, Koch TH.
    Anticancer Res; 2001 Oct 26; 21(4A):2753-60. PubMed ID: 11724351
    [Abstract] [Full Text] [Related]

  • 15. Influence of the structure of new anthracycline antibiotics on their biological properties.
    Wasowska M, Oszczapowicz I, Wietrzyk J, Opolski A, Madej J, Dzimira S, Oszczapowicz J.
    Anticancer Res; 2005 Oct 26; 25(3B):2043-8. PubMed ID: 16158943
    [Abstract] [Full Text] [Related]

  • 16. The hydroxyl epimer of doxorubicin controls the rate of formation of cytotoxic anthracycline-DNA adducts.
    Forrest RA, Swift LP, Evison BJ, Rephaeli A, Nudelman A, Phillips DR, Cutts SM.
    Cancer Chemother Pharmacol; 2013 Mar 26; 71(3):809-16. PubMed ID: 23263186
    [Abstract] [Full Text] [Related]

  • 17. [14-O-hemiesters and 13-hydrazones of anthracyline antibiotics of the daunorubicin series. Synthesis and cytostatic activity with respect to tumor cells sensitive or resistant to doxorubicin].
    Povarov LS, Leont'eva OV, Bernaki PD, Olsuf'eva EN, Salimova EI, Pera P, Preobrazhenskaia MN.
    Bioorg Khim; 1995 Dec 26; 21(12):925-32. PubMed ID: 8602889
    [Abstract] [Full Text] [Related]

  • 18. Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance.
    Veitch ZW, Guo B, Hembruff SL, Bewick AJ, Heibein AD, Eng J, Cull S, Maclean DA, Parissenti AM.
    Pharmacogenet Genomics; 2009 Jun 26; 19(6):477-88. PubMed ID: 19440163
    [Abstract] [Full Text] [Related]

  • 19. Effect of structural modifications of anthracyclines on the ability to overcome drug resistance of cancer cells.
    Wasowska M, Wietrzyk J, Opolski A, Oszczapowicz J, Oszczapowicz I.
    Anticancer Res; 2006 Jun 26; 26(3A):2009-12. PubMed ID: 16827137
    [Abstract] [Full Text] [Related]

  • 20. Prodrugs of anthracyclines for use in antibody-directed enzyme prodrug therapy.
    Florent JC, Dong X, Gaudel G, Mitaku S, Monneret C, Gesson JP, Jacquesy JC, Mondon M, Renoux B, Andrianomenjanahary S, Michel S, Koch M, Tillequin F, Gerken M, Czech J, Straub R, Bosslet K.
    J Med Chem; 1998 Sep 10; 41(19):3572-81. PubMed ID: 9733483
    [Abstract] [Full Text] [Related]

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