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156 related items for PubMed ID: 9565154

  • 1. Genetic treatment of severe hemoglobinopathies: the combat against transgene variegation and transgene silencing.
    Rivella S, Sadelain M.
    Semin Hematol; 1998 Apr; 35(2):112-25. PubMed ID: 9565154
    [Abstract] [Full Text] [Related]

  • 2. Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice.
    Tan M, Qing K, Zhou S, Yoder MC, Srivastava A.
    Mol Ther; 2001 Jun; 3(6):940-6. PubMed ID: 11407908
    [Abstract] [Full Text] [Related]

  • 3. Progress toward the genetic treatment of the beta-thalassemias.
    Sadelain M, Lisowski L, Samakoglu S, Rivella S, May C, Riviere I.
    Ann N Y Acad Sci; 2005 Jun; 1054():78-91. PubMed ID: 16339654
    [Abstract] [Full Text] [Related]

  • 4. Globin gene transfer for treatment of the beta-thalassemias and sickle cell disease.
    Sadelain M, Rivella S, Lisowski L, Samakoglu S, Rivière I.
    Best Pract Res Clin Haematol; 2004 Sep; 17(3):517-34. PubMed ID: 15498721
    [Abstract] [Full Text] [Related]

  • 5. Recent advances in globin gene transfer for the treatment of beta-thalassemia and sickle cell anemia.
    Sadelain M.
    Curr Opin Hematol; 2006 May; 13(3):142-8. PubMed ID: 16567956
    [Abstract] [Full Text] [Related]

  • 6. Expression of an anti-sickling beta-globin in human erythroblasts derived from retrovirally transduced primitive normal and sickle cell disease hematopoietic cells.
    Oh IH, Fabry ME, Humphries RK, Pawliuk R, Leboulch P, Hoffman R, Nagel RL, Eaves C.
    Exp Hematol; 2004 May; 32(5):461-9. PubMed ID: 15145214
    [Abstract] [Full Text] [Related]

  • 7. [Retroviral transfer of a human beta-globin gene linked to beta locus control region hypersensitive site 2 into murine hematopoietic stem cells].
    Zhai J, Liu D, Wang J.
    Zhonghua Yi Xue Za Zhi; 1999 Feb; 79(2):121-4. PubMed ID: 11601018
    [Abstract] [Full Text] [Related]

  • 8. Successful correction of the human Cooley's anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator.
    Malik P, Arumugam PI, Yee JK, Puthenveetil G.
    Ann N Y Acad Sci; 2005 Feb; 1054():238-49. PubMed ID: 16339671
    [Abstract] [Full Text] [Related]

  • 9. In vivo silencing of the human gamma-globin gene in murine erythroid cells following retroviral transduction.
    Lung HY, Meeus IS, Weinberg RS, Atweh GF.
    Blood Cells Mol Dis; 2000 Dec; 26(6):613-9. PubMed ID: 11358353
    [Abstract] [Full Text] [Related]

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  • 11. High-level sustained transgene expression in human embryonic stem cells using lentiviral vectors.
    Ma Y, Ramezani A, Lewis R, Hawley RG, Thomson JA.
    Stem Cells; 2003 Dec; 21(1):111-7. PubMed ID: 12529558
    [Abstract] [Full Text] [Related]

  • 12. A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference.
    Samakoglu S, Lisowski L, Budak-Alpdogan T, Usachenko Y, Acuto S, Di Marzo R, Maggio A, Zhu P, Tisdale JF, Rivière I, Sadelain M.
    Nat Biotechnol; 2006 Jan; 24(1):89-94. PubMed ID: 16378095
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  • 15. Lineage control of an integration site-dependent transgene combined with the beta-globin locus control region.
    Bonnerot C, Nicolas JF.
    C R Acad Sci III; 1993 Jan; 316(4):352-7. PubMed ID: 8402261
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  • 17. High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector.
    Gao Z, Golob J, Tanavde VM, Civin CI, Hawley RG, Cheng L.
    Stem Cells; 2001 Jan; 19(3):247-59. PubMed ID: 11359950
    [Abstract] [Full Text] [Related]

  • 18. Position-independent human beta-globin gene expression mediated by a recombinant adeno-associated virus vector carrying the chicken beta-globin insulator.
    Inoue T, Yamaza H, Sakai Y, Mizuno S, Ohno M, Hamasaki N, Fukumaki Y.
    J Hum Genet; 1999 Jan; 44(3):152-62. PubMed ID: 10319578
    [Abstract] [Full Text] [Related]

  • 19. Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin.
    May C, Rivella S, Callegari J, Heller G, Gaensler KM, Luzzatto L, Sadelain M.
    Nature; 2000 Jul 06; 406(6791):82-6. PubMed ID: 10894546
    [Abstract] [Full Text] [Related]

  • 20. Development of a condensed locus control region cassette and testing in retrovirus vectors for A gamma-globin.
    Emery DW, Chen H, Li Q, Stamatoyannopoulos G.
    Blood Cells Mol Dis; 1998 Sep 06; 24(3):322-39. PubMed ID: 10087991
    [Abstract] [Full Text] [Related]

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