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1030 related items for PubMed ID: 9565634

  • 1. The phosphotyrosine phosphatase SHP-2 participates in a multimeric signaling complex and regulates T cell receptor (TCR) coupling to the Ras/mitogen-activated protein kinase (MAPK) pathway in Jurkat T cells.
    Frearson JA, Alexander DR.
    J Exp Med; 1998 May 04; 187(9):1417-26. PubMed ID: 9565634
    [Abstract] [Full Text] [Related]

  • 2. CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.
    Perez-Villar JJ, Whitney GS, Bowen MA, Hewgill DH, Aruffo AA, Kanner SB.
    Mol Cell Biol; 1999 Apr 04; 19(4):2903-12. PubMed ID: 10082557
    [Abstract] [Full Text] [Related]

  • 3. SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity.
    Cuevas B, Lu Y, Watt S, Kumar R, Zhang J, Siminovitch KA, Mills GB.
    J Biol Chem; 1999 Sep 24; 274(39):27583-9. PubMed ID: 10488096
    [Abstract] [Full Text] [Related]

  • 4. Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.
    Kim H, Baumann H.
    Mol Cell Biol; 1999 Aug 24; 19(8):5326-38. PubMed ID: 10409724
    [Abstract] [Full Text] [Related]

  • 5. IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2.
    Gadina M, Sudarshan C, O'Shea JJ.
    J Immunol; 1999 Feb 15; 162(4):2081-6. PubMed ID: 9973481
    [Abstract] [Full Text] [Related]

  • 6. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase.
    Pani G, Fischer KD, Mlinaric-Rascan I, Siminovitch KA.
    J Exp Med; 1996 Sep 01; 184(3):839-52. PubMed ID: 9064344
    [Abstract] [Full Text] [Related]

  • 7. Ligation of CD28 stimulates the formation of a multimeric signaling complex involving grb-2-associated binder 2 (gab2), SRC homology phosphatase-2, and phosphatidylinositol 3-kinase: evidence that negative regulation of CD28 signaling requires the gab2 pleckstrin homology domain.
    Parry RV, Whittaker GC, Sims M, Edmead CE, Welham MJ, Ward SG.
    J Immunol; 2006 Jan 01; 176(1):594-602. PubMed ID: 16365455
    [Abstract] [Full Text] [Related]

  • 8. SH2 domain containing protein tyrosine phosphatase 2 regulates concanavalin A-dependent secretion and activation of matrix metalloproteinase 2 via the extracellular signal-regulated kinase and p38 pathways.
    Ruhul Amin AR, Oo ML, Senga T, Suzuki N, Feng GS, Hamaguchi M.
    Cancer Res; 2003 Oct 01; 63(19):6334-9. PubMed ID: 14559821
    [Abstract] [Full Text] [Related]

  • 9. The Src-homology domain 2-bearing protein tyrosine phosphatase-1 inhibits antigen receptor-induced apoptosis of activated peripheral T cells.
    Zhang J, Somani AK, Watt S, Mills GB, Siminovitch KA.
    J Immunol; 1999 Jun 01; 162(11):6359-67. PubMed ID: 10352248
    [Abstract] [Full Text] [Related]

  • 10. Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
    Yamasaki S, Nishida K, Hibi M, Sakuma M, Shiina R, Takeuchi A, Ohnishi H, Hirano T, Saito T.
    J Biol Chem; 2001 Nov 30; 276(48):45175-83. PubMed ID: 11572860
    [Abstract] [Full Text] [Related]

  • 11. Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells.
    von Willebrand M, Williams S, Tailor P, Mustelin T.
    Cell Signal; 1998 Jun 30; 10(6):407-13. PubMed ID: 9720763
    [Abstract] [Full Text] [Related]

  • 12. Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase.
    Takahashi-Tezuka M, Yoshida Y, Fukada T, Ohtani T, Yamanaka Y, Nishida K, Nakajima K, Hibi M, Hirano T.
    Mol Cell Biol; 1998 Jul 30; 18(7):4109-17. PubMed ID: 9632795
    [Abstract] [Full Text] [Related]

  • 13. Roles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activation.
    Takada T, Matozaki T, Takeda H, Fukunaga K, Noguchi T, Fujioka Y, Okazaki I, Tsuda M, Yamao T, Ochi F, Kasuga M.
    J Biol Chem; 1998 Apr 10; 273(15):9234-42. PubMed ID: 9535915
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  • 15. Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation.
    Su MW, Yu CL, Burakoff SJ, Jin YJ.
    J Immunol; 2001 Mar 15; 166(6):3975-82. PubMed ID: 11238643
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  • 17. Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
    Ling Y, Maile LA, Lieskovska J, Badley-Clarke J, Clemmons DR.
    Mol Biol Cell; 2005 Jul 15; 16(7):3353-64. PubMed ID: 15888547
    [Abstract] [Full Text] [Related]

  • 18. Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.
    Brockdorff J, Williams S, Couture C, Mustelin T.
    Eur J Immunol; 1999 Aug 15; 29(8):2539-50. PubMed ID: 10458769
    [Abstract] [Full Text] [Related]

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  • 20. The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases.
    Shi ZQ, Lu W, Feng GS.
    J Biol Chem; 1998 Feb 27; 273(9):4904-8. PubMed ID: 9478933
    [Abstract] [Full Text] [Related]


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